564,799 research outputs found
Scaling functions and amplitude ratios for the Potts model on an uncorrelated scale-free network
We study the critical behaviour of the -state Potts model on an
uncorrelated scale-free network having a power-law node degree distribution
with a decay exponent . Previous data show that the phase diagram of
the model in the plane in the second order phase transition regime
contains three regions, each being characterized by a different set of critical
exponents. In this paper we complete these results by finding analytic
expressions for the scaling functions and critical amplitude ratios in the
above mentioned regions. Similar to the previously found critical exponents,
the scaling functions and amplitude ratios appear to be -dependent. In
this way, we give a comprehensive description of the critical behaviour in a
new universality class.Comment: 10 pages, 4 figure
Corporate responsibility champions network: A 'how to' guide
This guide aims to show the what, why, and how of a CR champion and related networks. CR
champions are emerging as a powerful tool available for embedding CR philosophy into an
organisation, proving critical in the process of embedding CR.They play a strategic role, committed to
causing change and to continuing the work in the long-term.A CR champion network takes time and
effort to build but the use of champions, as one within a number of tactics to embed CR, has several
clear advantages: by working directly with staff on initiatives champions can engage staff and become
themselves more committed; champions connect divisions and regions, thus finding and propagating
best CR practices and ideas; and they allow for a credible two-way interface between global and local
in international companies
Interregional compensatory mechanisms of motor functioning in progressing preclinical neurodegeneration.
Understanding brain reserve in preclinical stages of neurodegenerative disorders allows determination of which brain regions contribute to normal functioning despite accelerated neuronal loss. Besides the recruitment of additional regions, a reorganisation and shift of relevance between normally engaged regions are a suggested key mechanism. Thus, network analysis methods seem critical for investigation of changes in directed causal interactions between such candidate brain regions. To identify core compensatory regions, fifteen preclinical patients carrying the genetic mutation leading to Huntington's disease and twelve controls underwent fMRI scanning. They accomplished an auditory paced finger sequence tapping task, which challenged cognitive as well as executive aspects of motor functioning by varying speed and complexity of movements. To investigate causal interactions among brain regions a single Dynamic Causal Model (DCM) was constructed and fitted to the data from each subject. The DCM parameters were analysed using statistical methods to assess group differences in connectivity, and the relationship between connectivity patterns and predicted years to clinical onset was assessed in gene carriers. In preclinical patients, we found indications for neural reserve mechanisms predominantly driven by bilateral dorsal premotor cortex, which increasingly activated superior parietal cortices the closer individuals were to estimated clinical onset. This compensatory mechanism was restricted to complex movements characterised by high cognitive demand. Additionally, we identified task-induced connectivity changes in both groups of subjects towards pre- and caudal supplementary motor areas, which were linked to either faster or more complex task conditions. Interestingly, coupling of dorsal premotor cortex and supplementary motor area was more negative in controls compared to gene mutation carriers. Furthermore, changes in the connectivity pattern of gene carriers allowed prediction of the years to estimated disease onset in individuals. Our study characterises the connectivity pattern of core cortical regions maintaining motor function in relation to varying task demand. We identified connections of bilateral dorsal premotor cortex as critical for compensation as well as task-dependent recruitment of pre- and caudal supplementary motor area. The latter finding nicely mirrors a previously published general linear model-based analysis of the same data. Such knowledge about disease specific inter-regional effective connectivity may help identify foci for interventions based on transcranial magnetic stimulation designed to stimulate functioning and also to predict their impact on other regions in motor-associated networks
ROME/REA : a gravitational microlensing search for exoplanets beyond the snow line on a global network of robotic telescopes
Funding: KH acknowledges support from STFC grant ST/R000824/1.Planet population synthesis models predict an abundance of planets with semimajor axes between 1 and 10 au, yet they lie at the edge of the detection limits of most planet finding techniques. Discovering these planets and studying their distribution is critical to understanding the physical processes that drive planet formation. ROME/REA is a gravitational microlensing project whose main science driver is to discover exoplanets in the cold outer regions of planetary systems. To achieve this, it uses a novel approach combining a multiband survey with reactive follow-up observations, exploiting the unique capabilities of the Las Cumbres Observatory global network of robotic telescopes combined with a Target and Observation Manager system. We present the main science objectives and a technical overview of the project, including initial results.PostprintPeer reviewe
Studying the Role of Human Parietal Cortex in Visuospatial Attention with Concurrent TMS-fMRI
Combining transcranial magnetic stimulation (TMS) with concurrent functional magnetic resonance imaging (fMRI) allows study of how local brain stimulation may causally affect activity in remote brain regions. Here, we applied bursts of high- or low-intensity TMS over right posterior parietal cortex, during a task requiring sustained covert visuospatial attention to either the left or right hemifield, or in a neutral control condition, while recording blood oxygenation-level-dependent signal with a posterior MR surface coil. As expected, the active attention conditions activated components of the well-described "attention network,” as compared with the neutral baseline. Also as expected, when comparing left minus right attention, or vice versa, contralateral occipital visual cortex was activated. The critical new finding was that the impact of high- minus low-intensity parietal TMS upon these visual regions depended on the currently attended side. High- minus low-intensity parietal TMS increased the difference between contralateral versus ipsilateral attention in right extrastriate visual cortex. A related albeit less pronounced pattern was found for left extrastriate visual cortex. Our results confirm that right human parietal cortex can exert attention-dependent influences on occipital visual cortex and provide a proof of concept for the use of concurrent TMS-fMRI in studying how remote influences can vary in a purely top-down manner with attentional demand
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