4,314 research outputs found

    Modeling Financial Time Series with Artificial Neural Networks

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    Financial time series convey the decisions and actions of a population of human actors over time. Econometric and regressive models have been developed in the past decades for analyzing these time series. More recently, biologically inspired artificial neural network models have been shown to overcome some of the main challenges of traditional techniques by better exploiting the non-linear, non-stationary, and oscillatory nature of noisy, chaotic human interactions. This review paper explores the options, benefits, and weaknesses of the various forms of artificial neural networks as compared with regression techniques in the field of financial time series analysis.CELEST, a National Science Foundation Science of Learning Center (SBE-0354378); SyNAPSE program of the Defense Advanced Research Project Agency (HR001109-03-0001

    Estimation and prediction of temperature in Iraq using the multi-layered neural network model

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    The forecasting using the multi-layered neural network model is one of the methods used recently in forecasting, especially in climate forecasts for certain regions, because of its accuracy in forecasting, which sometimes reaches levels close to the real collected data. In this research, the daily temperatures in the climate of Iraq were predicted, by taking data from the Iraqi Meteorological Authority by (228) observations, which represent the daily temperatures of Karbala Governorate in the year (2021), The results of the autocorrelation and partial autocorrelation showed that the daily temperature series of Karbala governorate is unstable, and this was confirmed by conducting the augmented Dickey Fuller test. The data was analyzed using the multi-layered neural network model in two stages, and it was later shown that the accuracy of estimation and prediction using the multi-layered neural network even if the time series is not stable, The results showed an indication of an rising increase in temperatures during the coming years. The researcher concluded that it is necessary to pay attention to the vegetation cover and to conduct many predictive studies of the climate using the multi-layered neural network

    Using High-Order Prior Belief Predictions in Hierarchical Temporal Memory for Streaming Anomaly Detection

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    Autonomous streaming anomaly detection can have a significant impact in any domain where continuous, real-time data is common. Often in these domains, datasets are too large or complex to hand label. Algorithms that require expensive global training procedures and large training datasets impose strict demands on data and are accordingly not fit to scale to real-time applications that are noisy and dynamic. Unsupervised algorithms that learn continuously like humans therefore boast increased applicability to these real-world scenarios. Hierarchical Temporal Memory (HTM) is a biologically constrained theory of machine intelligence inspired by the structure, activity, organization and interaction of pyramidal neurons in the neocortex of the primate brain. At the core of HTM are spatio-temporal learning algorithms that store, learn, recall and predict temporal sequences in an unsupervised and continuous fashion to meet the demands of real-time tasks. Unlike traditional machine learning and deep learning encompassed by the act of complex functional approximation, HTM with the surrounding proposed framework does not require any offline training procedures, any massive stores of training data, any data labels, it does not catastrophically forget previously learned information and it need only make one pass through the temporal data. Proposed in this thesis is an algorithmic framework built upon HTM for intelligent streaming anomaly detection. Unseen in earlier streaming anomaly detection work, the proposed framework uses high-order prior belief predictions in time in the effort to increase the fault tolerance and complex temporal anomaly detection capabilities of the underlying time-series model. Experimental results suggest that the framework when built upon HTM redefines state-of-the-art performance in a popular streaming anomaly benchmark. Comparative results with and without the framework on several third-party datasets collected from real-world scenarios also show a clear performance benefit. In principle, the proposed framework can be applied to any time-series modeling algorithm capable of producing high-order predictions

    MicroRNA Profiling and Bioinformatics Target Analysis in Dorsal Hippocampus of Chronically Stressed Rats: Relevance to Depression Pathophysiology

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    IndexaciĂłn: Scopus.1Laboratory of Neuroplasticity and Neurogenetics, Faculty of Chemical and Pharmaceutical Sciences, Department of Biochemistry and Molecular Biology, Universidad de Chile, Santiago, Chile, 2National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Durham, NC, United States, 3Centro de GenĂłmica y BioinformĂĄtica, Facultad de Ciencias, Universidad Mayor, Santiago, Chile, 4Millennium Institute for Integrative Biology (iBio), FONDAP Center for Genome Regulation, Departamento de GenĂ©tica Molecular y MicrobiologĂ­a, Pontificia Universidad CatĂłlica de Chile, Santiago, Chile, 5Department of Kinesiology, Faculty of Health Sciences, Universidad CatĂłlica del Maule, Talca, Chile, 6Escuela de QuĂ­mica y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago, Chile.This study was supported by the following grants: FONDECYT 1120528 (JLF), Fondo Central de InvestigaciĂłn, Universidad de Chile ENL025/16 (JLF), ES090079 (JAC). Research in RG and EV laboratories is funded by Instituto Milenio iBio – Iniciativa CientĂ­fica Milenio MINECON.Studies conducted in rodents subjected to chronic stress and some observations in humans after psychosocial stress, have allowed to establish a link between stress and the susceptibility to many complex diseases, including mood disorders. The studies in rodents have revealed that chronic exposure to stress negatively affects synaptic plasticity by triggering changes in the production of trophic factors, subunit levels of glutamate ionotropic receptors, neuron morphology, and neurogenesis in the adult hippocampus. These modifications may account for the impairment in learning and memory processes observed in chronically stressed animals. It is plausible then, that stress modifies the interplay between signal transduction cascades and gene expression regulation in the hippocampus, therefore leading to altered neuroplasticity and functioning of neural circuits. Considering that miRNAs play an important role in post-transcriptional-regulation of gene expression and participate in several hippocampus-dependent functions; we evaluated the consequences of chronic stress on the expression of miRNAs in dorsal (anterior) portion of the hippocampus, which participates in memory formation in rodents. Here, we show that male rats exposed to daily restraint stress (2.5 h/day) during 7 and 14 days display a differential profile of miRNA levels in dorsal hippocampus and remarkably, we found that some of these miRNAs belong to the miR-379-410 cluster. We confirmed a rise in miR-92a and miR-485 levels after 14 days of stress by qPCR, an effect that was not mimicked by chronic administration of corticosterone (14 days). Our in silico study identified the top-10 biological functions influenced by miR-92a, nine of which were shared with miR-485: Nervous system development and function, Tissue development, Behavior, Embryonic development, Organ development, Organismal development, Organismal survival, Tissue morphology, and Organ morphology. Furthermore, our in silico study provided a landscape of potential miRNA-92a and miR-485 targets, along with relevant canonical pathways related to axonal guidance signaling and cAMP signaling, which may influence the functioning of several neuroplastic substrates in dorsal hippocampus. Additionally, the combined effect of miR-92a and miR-485 on transcription factors, along with histone-modifying enzymes, may have a functional relevance by producing changes in gene regulatory networks that modify the neuroplastic capacity of the adult dorsal hippocampus under stress. © 2018 Muñoz-Llanos, GarcĂ­a-PĂ©rez, Xu, Tejos-Bravo, Vidal, Moyano, GutiĂ©rrez, Aguayo, Pacheco, GarcĂ­a-Rojo, Aliaga, Rojas, Cidlowski and Fiedler.https://www.frontiersin.org/articles/10.3389/fnmol.2018.00251/ful

    A Multi-In and Multi-Out Dendritic Neuron Model and its Optimization

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    Artificial neural networks (ANNs), inspired by the interconnection of real neurons, have achieved unprecedented success in various fields such as computer vision and natural language processing. Recently, a novel mathematical ANN model, known as the dendritic neuron model (DNM), has been proposed to address nonlinear problems by more accurately reflecting the structure of real neurons. However, the single-output design limits its capability to handle multi-output tasks, significantly lowering its applications. In this paper, we propose a novel multi-in and multi-out dendritic neuron model (MODN) to tackle multi-output tasks. Our core idea is to introduce a filtering matrix to the soma layer to adaptively select the desired dendrites to regress each output. Because such a matrix is designed to be learnable, MODN can explore the relationship between each dendrite and output to provide a better solution to downstream tasks. We also model a telodendron layer into MODN to simulate better the real neuron behavior. Importantly, MODN is a more general and unified framework that can be naturally specialized as the DNM by customizing the filtering matrix. To explore the optimization of MODN, we investigate both heuristic and gradient-based optimizers and introduce a 2-step training method for MODN. Extensive experimental results performed on 11 datasets on both binary and multi-class classification tasks demonstrate the effectiveness of MODN, with respect to accuracy, convergence, and generality

    Experience-driven formation of parts-based representations in a model of layered visual memory

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    Growing neuropsychological and neurophysiological evidence suggests that the visual cortex uses parts-based representations to encode, store and retrieve relevant objects. In such a scheme, objects are represented as a set of spatially distributed local features, or parts, arranged in stereotypical fashion. To encode the local appearance and to represent the relations between the constituent parts, there has to be an appropriate memory structure formed by previous experience with visual objects. Here, we propose a model how a hierarchical memory structure supporting efficient storage and rapid recall of parts-based representations can be established by an experience-driven process of self-organization. The process is based on the collaboration of slow bidirectional synaptic plasticity and homeostatic unit activity regulation, both running at the top of fast activity dynamics with winner-take-all character modulated by an oscillatory rhythm. These neural mechanisms lay down the basis for cooperation and competition between the distributed units and their synaptic connections. Choosing human face recognition as a test task, we show that, under the condition of open-ended, unsupervised incremental learning, the system is able to form memory traces for individual faces in a parts-based fashion. On a lower memory layer the synaptic structure is developed to represent local facial features and their interrelations, while the identities of different persons are captured explicitly on a higher layer. An additional property of the resulting representations is the sparseness of both the activity during the recall and the synaptic patterns comprising the memory traces.Comment: 34 pages, 12 Figures, 1 Table, published in Frontiers in Computational Neuroscience (Special Issue on Complex Systems Science and Brain Dynamics), http://www.frontiersin.org/neuroscience/computationalneuroscience/paper/10.3389/neuro.10/015.2009
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