756 research outputs found

    Anomaly Detection Based on Indicators Aggregation

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    Automatic anomaly detection is a major issue in various areas. Beyond mere detection, the identification of the source of the problem that produced the anomaly is also essential. This is particularly the case in aircraft engine health monitoring where detecting early signs of failure (anomalies) and helping the engine owner to implement efficiently the adapted maintenance operations (fixing the source of the anomaly) are of crucial importance to reduce the costs attached to unscheduled maintenance. This paper introduces a general methodology that aims at classifying monitoring signals into normal ones and several classes of abnormal ones. The main idea is to leverage expert knowledge by generating a very large number of binary indicators. Each indicator corresponds to a fully parametrized anomaly detector built from parametric anomaly scores designed by experts. A feature selection method is used to keep only the most discriminant indicators which are used at inputs of a Naive Bayes classifier. This give an interpretable classifier based on interpretable anomaly detectors whose parameters have been optimized indirectly by the selection process. The proposed methodology is evaluated on simulated data designed to reproduce some of the anomaly types observed in real world engines.Comment: International Joint Conference on Neural Networks (IJCNN 2014), Beijing : China (2014). arXiv admin note: substantial text overlap with arXiv:1407.088

    Ultra low power wearable sleep diagnostic systems

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    Sleep disorders are studied using sleep study systems called Polysomnography that records several biophysical parameters during sleep. However, these are bulky and are typically located in a medical facility where patient monitoring is costly and quite inefficient. Home-based portable systems solve these problems to an extent but they record only a minimal number of channels due to limited battery life. To surmount this, wearable sleep system are desired which need to be unobtrusive and have long battery life. In this thesis, a novel sleep system architecture is presented that enables the design of an ultra low power sleep diagnostic system. This architecture is capable of extending the recording time to 120 hours in a wearable system which is an order of magnitude improvement over commercial wearable systems that record for about 12 hours. This architecture has in effect reduced the average power consumption of 5-6 mW per channel to less than 500 uW per channel. This has been achieved by eliminating sampled data architecture, reducing the wireless transmission rate and by moving the sleep scoring to the sensors. Further, ultra low power instrumentation amplifiers have been designed to operate in weak inversion region to support this architecture. A 40 dB chopper-stabilised low power instrumentation amplifiers to process EEG were designed and tested to operate from 1.0 V consuming just 3.1 uW for peak mode operation with DC servo loop. A 50 dB non-EEG amplifier continuous-time bandpass amplifier with a consumption of 400 nW was also fabricated and tested. Both the amplifiers achieved a high CMRR and impedance that are critical for wearable systems. Combining these amplifiers with the novel architecture enables the design of an ultra low power sleep recording system. This reduces the size of the battery required and hence enables a truly wearable system.Open Acces

    Objective localisation of oral mucosal lesions using optical coherence tomography.

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    PhDIdentification of the most representative location for biopsy is critical in establishing the definitive diagnosis of oral mucosal lesions. Currently, this process involves visual evaluation of the colour characteristics of tissue aided by topical application of contrast enhancing agents. Although, this approach is widely practiced, it remains limited by its lack of objectivity in identifying and delineating suspicious areas for biopsy. To overcome this drawback there is a need to introduce a technique that would provide macroscopic guidance based on microscopic imaging and analysis. Optical Coherence Tomography is an emerging high resolution biomedical imaging modality that can potentially be used as an in vivo tool for selection of the most appropriate site for biopsy. This thesis investigates the use of OCT for qualitative and quantitative mapping of oral mucosal lesions. Feasibility studies were performed on patient biopsy samples prior to histopathological processing using a commercial OCT microscope. Qualitative imaging results examining a variety of normal, benign, inflammatory and premalignant lesions of the oral mucosa will be presented. Furthermore, the identification and utilisation of a common quantifiable parameter in OCT and histology of images of normal and dysplastic oral epithelium will be explored thus ensuring objective and reproducible mapping of the progression of oral carcinogenesis. Finally, the selection of the most representative biopsy site of oral epithelial dysplasia would be investigated using a novel approach, scattering attenuation microscopy. It is hoped this approach may help convey more clinical meaning than the conventional visualisation of OCT images
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