A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Backtracking Spatial Pyramid Pooling (SPP)-based Image Classifier for Weakly Supervised Top-down Salient Object Detection

Top-down saliency models produce a probability map that peaks at target locations specified by a task/goal such as object detection. They are usually trained in a fully supervised setting involving pixel-level annotations of objects. We propose a weakly supervised top-down saliency framework using only binary labels that indicate the presence/absence of an object in an image. First, the probabilistic contribution of each image region to the confidence of a CNN-based image classifier is computed through a backtracking strategy to produce top-down saliency. From a set of saliency maps of an image produced by fast bottom-up saliency approaches, we select the best saliency map suitable for the top-down task. The selected bottom-up saliency map is combined with the top-down saliency map. Features having high combined saliency are used to train a linear SVM classifier to estimate feature saliency. This is integrated with combined saliency and further refined through a multi-scale superpixel-averaging of saliency map. We evaluate the performance of the proposed weakly supervised topdown saliency and achieve comparable performance with fully supervised approaches. Experiments are carried out on seven challenging datasets and quantitative results are compared with 40 closely related approaches across 4 different applications.Comment: 14 pages, 7 figure

Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table