26,041 research outputs found
Survival and disinfection of SARS-Cov-2 in environment and contaminated surface
The detection of SARS-Cov-2 in the sewage and water resources has increased the awareness among the people about the possibility survival of SARS-Cov-2 in the environment and the potential to transmit into the human through food chain or water resources. Moreover, the surface contaminated by the virus need to be disinfected frequently by using an effective disinfectant, the current chapter discussed the efficiency of the most traditional treatment process of the sewage and wastewater, and their role in the elimination of the virus as well as the sterility assurance level concept. Moreover, the chemical disinfectant used currently and their temporary efficiency has been reviewed
Second-generation PLINK: rising to the challenge of larger and richer datasets
PLINK 1 is a widely used open-source C/C++ toolset for genome-wide
association studies (GWAS) and research in population genetics. However, the
steady accumulation of data from imputation and whole-genome sequencing studies
has exposed a strong need for even faster and more scalable implementations of
key functions. In addition, GWAS and population-genetic data now frequently
contain probabilistic calls, phase information, and/or multiallelic variants,
none of which can be represented by PLINK 1's primary data format.
To address these issues, we are developing a second-generation codebase for
PLINK. The first major release from this codebase, PLINK 1.9, introduces
extensive use of bit-level parallelism, O(sqrt(n))-time/constant-space
Hardy-Weinberg equilibrium and Fisher's exact tests, and many other algorithmic
improvements. In combination, these changes accelerate most operations by 1-4
orders of magnitude, and allow the program to handle datasets too large to fit
in RAM. This will be followed by PLINK 2.0, which will introduce (a) a new data
format capable of efficiently representing probabilities, phase, and
multiallelic variants, and (b) extensions of many functions to account for the
new types of information.
The second-generation versions of PLINK will offer dramatic improvements in
performance and compatibility. For the first time, users without access to
high-end computing resources can perform several essential analyses of the
feature-rich and very large genetic datasets coming into use.Comment: 2 figures, 1 additional fil
Fingerprint databases for theorems
We discuss the advantages of searchable, collaborative, language-independent
databases of mathematical results, indexed by "fingerprints" of small and
canonical data. Our motivating example is Neil Sloane's massively influential
On-Line Encyclopedia of Integer Sequences. We hope to encourage the greater
mathematical community to search for the appropriate fingerprints within each
discipline, and to compile fingerprint databases of results wherever possible.
The benefits of these databases are broad - advancing the state of knowledge,
enhancing experimental mathematics, enabling researchers to discover unexpected
connections between areas, and even improving the refereeing process for
journal publication.Comment: to appear in Notices of the AM
- …