Wearable Platform for Automatic Recognition of Parkinson Disease by Muscular Implication Monitoring

The need for diagnostic tools for the characterization of progressive movement disorders - as the Parkinson Disease (PD) - aiming to early detect and monitor the pathology is getting more and more impelling. The parallel request of wearable and wireless solutions, for the real-time monitoring in a non-controlled environment, has led to the implementation of a Quantitative Gait Analysis platform for the extraction of muscular implications features in ordinary motor action, such as gait. The here proposed platform is used for the quantification of PD symptoms. Addressing the wearable trend, the proposed architecture is able to define the real-time modulation of the muscular indexes by using 8 EMG wireless nodes positioned on lower limbs. The implemented system “translates” the acquisition in a 1-bit signal, exploiting a dynamic thresholding algorithm. The resulting 1-bit signals are used both to define muscular indexes both to drastically reduce the amount of data to be analyzed, preserving at the same time the muscular information. The overall architecture has been fully implemented on Altera Cyclone V FPGA. The system has been tested on 4 subjects: 2 affected by PD and 2 healthy subjects (control group). The experimental results highlight the validity of the proposed solution in Disease recognition and the outcomes match the clinical literature results

An ambient assisted living solution for mobile environments

An Ambient Assisted Living (AAL) mobile health application solution with biofeedback based on body sensors is very useful to perform a data collection for diagnosis in patients whose clinical conditions are not favourable. This system allows comfort, mobility, and efficiency in all the process of data collection providing more confidence and operability. A physical fall may be considered something natural in the life span of a human being from birth to death. In a perfect scenario it would be possible to predict when a fall will occur in order to avoid it. Falls represent a high risk for senior people health. Those falls can cause fractures or injuries causing great dependence and debilitation to the elderly and even death in extreme cases. Falls can be detected by the accelerometer included in most of the available mobile phones or portable digital assistants (PDAs). To reverse this tendency, it can be obtained more accurate data for patients monitoring from the body sensors attached to the human body (such as, electrocardiogram (ECG), electromyography (EMG), blood volume pulse (BVP), electro dermal activity (EDA), and galvanic skin response (GSR)). Then, this dissertation reviews the related literature on this topic and introduces a mobile solution for falls prevention, detection, and biofeedback monitoring. The proposed system collects sensed data that is sent to a smartphone or tablet through Bluetooth. Mobile devices are used to process and display information graphically to users. The falls prevention system uses collected data from sensors in order to control and advice the patient or even to give instructions to treat an abnormal condition to reduce the falls risk. In cases of symptoms that last more time it can even detect a possible disease. The signal processing algorithms plays a key role in the fall prevention system. These algorithms in real time, through the capture of biofeedback data, are needed to extract relevant information from the signals detected to warn the patient. Monitoring and processing data from sensors is realized by a smartphone or tablet that will send warnings to users. All the process is performed in real time. These mobile devices are also used as a gateway to send the collected data to a Web service, which subsequently allows data storage and consultation. The proposed system is evaluated, demonstrated, and validated through a prototype and it is ready for use

Fall Prediction and Prevention Systems: Recent Trends, Challenges, and Future Research Directions.

Fall prediction is a multifaceted problem that involves complex interactions between physiological, behavioral, and environmental factors. Existing fall detection and prediction systems mainly focus on physiological factors such as gait, vision, and cognition, and do not address the multifactorial nature of falls. In addition, these systems lack efficient user interfaces and feedback for preventing future falls. Recent advances in internet of things (IoT) and mobile technologies offer ample opportunities for integrating contextual information about patient behavior and environment along with physiological health data for predicting falls. This article reviews the state-of-the-art in fall detection and prediction systems. It also describes the challenges, limitations, and future directions in the design and implementation of effective fall prediction and prevention systems

Wearable Fall Detector Using Recurrent Neural Networks

Falls have become a relevant public health issue due to their high prevalence and negative effects in elderly people. Wearable fall detector devices allow the implementation of continuous and ubiquitous monitoring systems. The effectiveness for analyzing temporal signals with low energy consumption is one of the most relevant characteristics of these devices. Recurrent neural networks (RNNs) have demonstrated a great accuracy in some problems that require analyzing sequential inputs. However, getting appropriate response times in low power microcontrollers remains a difficult task due to their limited hardware resources. This work shows a feasibility study about using RNN-based deep learning models to detect both falls and falls’ risks in real time using accelerometer signals. The effectiveness of four different architectures was analyzed using the SisFall dataset at different frequencies. The resulting models were integrated into two different embedded systems to analyze the execution times and changes in the model effectiveness. Finally, a study of power consumption was carried out. A sensitivity of 88.2% and a specificity of 96.4% was obtained. The simplest models reached inference times lower than 34 ms, which implies the capability to detect fall events in real-time with high energy efficiency. This suggests that RNN models provide an effective method that can be implemented in low power microcontrollers for the creation of autonomous wearable fall detection systems in real-time

An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for the conservative and nonpharmacological management of female pelvic floor dysfunction

There has been an increasing need for the terminology on the conservative management of female pelvic floor dysfunction to be collated in a clinically based consensus report.This Report combines the input of members and elected nominees of the Standardization and Terminology Committees of two International Organizations, the International Urogynecological Association (IUGA) and the International Continence Society (ICS), assisted at intervals by many external referees. An extensive process of nine rounds of internal and external review was developed to exhaustively examine each definition, with decision-making by collective opinion (consensus). Before opening up for comments on the webpages of ICS and IUGA, five experts from physiotherapy, neurology, urology, urogynecology, and nursing were invited to comment on the paper.A Terminology Report on the conservative management of female pelvic floor dysfunction, encompassing over 200 separate definitions, has been developed. It is clinically based, with the most common symptoms, signs, assessments, diagnoses, and treatments defined. Clarity and ease of use have been key aims to make it interpretable by practitioners and trainees in all the different specialty groups involved in female pelvic floor dysfunction. Ongoing review is not only anticipated, but will be required to keep the document updated and as widely acceptable as possible.A consensus-based terminology report for the conservative management of female pelvic floor dysfunction has been produced, aimed at being a significant aid to clinical practice and a stimulus for research

A Mobile Healthcare Solution for Ambient Assisted Living Environments

Elderly people need regular healthcare services and, several times, are dependent of physicians’ personal attendance. This dependence raises several issues to elders, such as, the need to travel and mobility support. Ambient Assisted Living (AAL) and Mobile Health (m-Health) services and applications offer good healthcare solutions that can be used both on indoor and in mobility environments. This dissertation presents an ambient assisted living (AAL) solution for mobile environments. It includes elderly biofeedback monitoring using body sensors for data collection offering support for remote monitoring. The used sensors are attached to the human body (such as the electrocardiogram, blood pressure, and temperature). They collect data providing comfort, mobility, and guaranteeing efficiency and data confidentiality. Periodic collection of patients’ data is important to gather more accurate measurements and to avoid common risky situations, like a physical fall may be considered something natural in life span and it is more dangerous for senior people. One fall can out a life in extreme cases or cause fractures, injuries, but when it is early detected through an accelerometer, for example, it can avoid a tragic outcome. The presented proposal monitors elderly people, storing collected data in a personal computer, tablet, or smartphone through Bluetooth. This application allows an analysis of possible health condition warnings based on the input of supporting charts, and real-time bio-signals monitoring and is able to warn users and the caretakers. These mobile devices are also used to collect data, which allow data storage and its possible consultation in the future. The proposed system is evaluated, demonstrated and validated through a prototype and it is ready for use. The watch Texas ez430-Chronos, which is capable to store information for later analysis and the sensors Shimmer who allow the creation of a personalized application that it is capable of measuring biosignals of the patient in real time is described throughout this dissertation

Fifteen years of wireless sensors for balance assessment in neurological disorders

Balance impairment is a major mechanism behind falling along with environmental hazards. Under physiological conditions, ageing leads to a progressive decline in balance control per se. Moreover, various neurological disorders further increase the risk of falls by deteriorating specific nervous system functions contributing to balance. Over the last 15 years, significant advancements in technology have provided wearable solutions for balance evaluation and the management of postural instability in patients with neurological disorders. This narrative review aims to address the topic of balance and wireless sensors in several neurological disorders, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, and other neurodegenerative and acute clinical syndromes. The review discusses the physiological and pathophysiological bases of balance in neurological disorders as well as the traditional and innovative instruments currently available for balance assessment. The technical and clinical perspectives of wearable technologies, as well as current challenges in the field of teleneurology, are also examined

Use of accelerometers in the control of practical prosthetic arms

Accelerometers can be used to augment the control of powered prosthetic arms. They can detect the orientation of the joint and limb and the controller can correct for the amount of torque required to move the limb. They can also be used to create a platform, with a fixed orientation relative to gravity for the object held in the hand. This paper describes three applications for this technology, in a powered wrist and powered arm. By adding sensors to the arm making these data available to the controller, the input from the user can be made simpler. The operator will not need to correct for changes in orientation of their body as they move. Two examples of the correction for orientation against gravity are described and an example of the system designed for use by a patient. The controller for all examples is a distributed set of microcontrollers, one node for each joint, linked with the Control Area Network (CAN) bus. The clinical arm uses a version of the Southampton Adaptive Manipulation Scheme to control the arm and hand. In this control form the user gives simpler input commands and leaves the detailed control of the arm to the controller