Factors Affecting Web Page Similarity

Abstract. Tools that allow effective information organisation, access and navigation are becoming increasingly important on the Web. Sim-ilarity between web pages is a concept that is central to such tools. In this paper, we examine the effect that content and layout-related as-pects of web pages have on web page similarity. We consider the textual content contained within common HTML tags, the structural layout of pages, and the query terms contained within pages. Our study shows that combinations of factors can yield more promising results than individual factors, and that different aspects of web pages affect similarities between pages in a different manner. We found a number of factors that, when taken into account, can result in effective measures of similarity between web pages. Query information in particular, proved to be important for the effective organisation of web pages.

Exploring Protein-Protein Interactions as Drug Targets for Anti-cancer Therapy with In Silico Workflows

We describe a computational protocol to aid the design of small molecule and peptide drugs that target protein-protein interactions, particularly for anti-cancer therapy. To achieve this goal, we explore multiple strategies, including finding binding hot spots, incorporating chemical similarity and bioactivity data, and sampling similar binding sites from homologous protein complexes. We demonstrate how to combine existing interdisciplinary resources with examples of semi-automated workflows. Finally, we discuss several major problems, including the occurrence of drug-resistant mutations, drug promiscuity, and the design of dual-effect inhibitors.Fil: Goncearenco, Alexander. National Institutes of Health; Estados UnidosFil: Li, Minghui. Soochow University; China. National Institutes of Health; Estados UnidosFil: Simonetti, Franco Lucio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; ArgentinaFil: Shoemaker, Benjamin A. National Institutes of Health; Estados UnidosFil: Panchenko, Anna R. National Institutes of Health; Estados Unido

Discovering the Impact of Knowledge in Recommender Systems: A Comparative Study

Recommender systems engage user profiles and appropriate filtering techniques to assist users in finding more relevant information over the large volume of information. User profiles play an important role in the success of recommendation process since they model and represent the actual user needs. However, a comprehensive literature review of recommender systems has demonstrated no concrete study on the role and impact of knowledge in user profiling and filtering approache. In this paper, we review the most prominent recommender systems in the literature and examine the impression of knowledge extracted from different sources. We then come up with this finding that semantic information from the user context has substantial impact on the performance of knowledge based recommender systems. Finally, some new clues for improvement the knowledge-based profiles have been proposed.Comment: 14 pages, 3 tables; International Journal of Computer Science & Engineering Survey (IJCSES) Vol.2, No.3, August 201

CHORUS Deliverable 2.2: Second report - identification of multi-disciplinary key issues for gap analysis toward EU multimedia search engines roadmap

After addressing the state-of-the-art during the first year of Chorus and establishing the existing landscape in multimedia search engines, we have identified and analyzed gaps within European research effort during our second year. In this period we focused on three directions, notably technological issues, user-centred issues and use-cases and socio- economic and legal aspects. These were assessed by two central studies: firstly, a concerted vision of functional breakdown of generic multimedia search engine, and secondly, a representative use-cases descriptions with the related discussion on requirement for technological challenges. Both studies have been carried out in cooperation and consultation with the community at large through EC concertation meetings (multimedia search engines cluster), several meetings with our Think-Tank, presentations in international conferences, and surveys addressed to EU projects coordinators as well as National initiatives coordinators. Based on the obtained feedback we identified two types of gaps, namely core technological gaps that involve research challenges, and “enablers”, which are not necessarily technical research challenges, but have impact on innovation progress. New socio-economic trends are presented as well as emerging legal challenges

Relating Web pages to enable information-gathering tasks

We argue that relationships between Web pages are functions of the user's intent. We identify a class of Web tasks - information-gathering - that can be facilitated by a search engine that provides links to pages which are related to the page the user is currently viewing. We define three kinds of intentional relationships that correspond to whether the user is a) seeking sources of information, b) reading pages which provide information, or c) surfing through pages as part of an extended information-gathering process. We show that these three relationships can be productively mined using a combination of textual and link information and provide three scoring mechanisms that correspond to them: {\em SeekRel}, {\em FactRel} and {\em SurfRel}. These scoring mechanisms incorporate both textual and link information. We build a set of capacitated subnetworks - each corresponding to a particular keyword - that mirror the interconnection structure of the World Wide Web. The scores are computed by computing flows on these subnetworks. The capacities of the links are derived from the {\em hub} and {\em authority} values of the nodes they connect, following the work of Kleinberg (1998) on assigning authority to pages in hyperlinked environments. We evaluated our scoring mechanism by running experiments on four data sets taken from the Web. We present user evaluations of the relevance of the top results returned by our scoring mechanisms and compare those to the top results returned by Google's Similar Pages feature, and the {\em Companion} algorithm proposed by Dean and Henzinger (1999).Comment: In Proceedings of ACM Hypertext 200