1,368 research outputs found
Neutrality: A Necessity for Self-Adaptation
Self-adaptation is used in all main paradigms of evolutionary computation to
increase efficiency. We claim that the basis of self-adaptation is the use of
neutrality. In the absence of external control neutrality allows a variation of
the search distribution without the risk of fitness loss.Comment: 6 pages, 3 figures, LaTe
Imputation Estimators Partially Correct for Model Misspecification
Inference problems with incomplete observations often aim at estimating
population properties of unobserved quantities. One simple way to accomplish
this estimation is to impute the unobserved quantities of interest at the
individual level and then take an empirical average of the imputed values. We
show that this simple imputation estimator can provide partial protection
against model misspecification. We illustrate imputation estimators' robustness
to model specification on three examples: mixture model-based clustering,
estimation of genotype frequencies in population genetics, and estimation of
Markovian evolutionary distances. In the final example, using a representative
model misspecification, we demonstrate that in non-degenerate cases, the
imputation estimator dominates the plug-in estimate asymptotically. We conclude
by outlining a Bayesian implementation of the imputation-based estimation.Comment: major rewrite, beta-binomial example removed, model based clustering
is added to the mixture model example, Bayesian approach is now illustrated
with the genetics exampl
The Evolutionary Unfolding of Complexity
We analyze the population dynamics of a broad class of fitness functions that
exhibit epochal evolution---a dynamical behavior, commonly observed in both
natural and artificial evolutionary processes, in which long periods of stasis
in an evolving population are punctuated by sudden bursts of change. Our
approach---statistical dynamics---combines methods from both statistical
mechanics and dynamical systems theory in a way that offers an alternative to
current ``landscape'' models of evolutionary optimization. We describe the
population dynamics on the macroscopic level of fitness classes or phenotype
subbasins, while averaging out the genotypic variation that is consistent with
a macroscopic state. Metastability in epochal evolution occurs solely at the
macroscopic level of the fitness distribution. While a balance between
selection and mutation maintains a quasistationary distribution of fitness,
individuals diffuse randomly through selectively neutral subbasins in genotype
space. Sudden innovations occur when, through this diffusion, a genotypic
portal is discovered that connects to a new subbasin of higher fitness
genotypes. In this way, we identify innovations with the unfolding and
stabilization of a new dimension in the macroscopic state space. The
architectural view of subbasins and portals in genotype space clarifies how
frozen accidents and the resulting phenotypic constraints guide the evolution
to higher complexity.Comment: 28 pages, 5 figure
Evolvability signatures of generative encodings: beyond standard performance benchmarks
Evolutionary robotics is a promising approach to autonomously synthesize
machines with abilities that resemble those of animals, but the field suffers
from a lack of strong foundations. In particular, evolutionary systems are
currently assessed solely by the fitness score their evolved artifacts can
achieve for a specific task, whereas such fitness-based comparisons provide
limited insights about how the same system would evaluate on different tasks,
and its adaptive capabilities to respond to changes in fitness (e.g., from
damages to the machine, or in new situations). To counter these limitations, we
introduce the concept of "evolvability signatures", which picture the
post-mutation statistical distribution of both behavior diversity (how
different are the robot behaviors after a mutation?) and fitness values (how
different is the fitness after a mutation?). We tested the relevance of this
concept by evolving controllers for hexapod robot locomotion using five
different genotype-to-phenotype mappings (direct encoding, generative encoding
of open-loop and closed-loop central pattern generators, generative encoding of
neural networks, and single-unit pattern generators (SUPG)). We observed a
predictive relationship between the evolvability signature of each encoding and
the number of generations required by hexapods to adapt from incurred damages.
Our study also reveals that, across the five investigated encodings, the SUPG
scheme achieved the best evolvability signature, and was always foremost in
recovering an effective gait following robot damages. Overall, our evolvability
signatures neatly complement existing task-performance benchmarks, and pave the
way for stronger foundations for research in evolutionary robotics.Comment: 24 pages with 12 figures in the main text, and 4 supplementary
figures. Accepted at Information Sciences journal (in press). Supplemental
videos are available online at, see http://goo.gl/uyY1R
Bridging scales in cancer progression: Mapping genotype to phenotype using neural networks
In this review we summarize our recent efforts in trying to understand the
role of heterogeneity in cancer progression by using neural networks to
characterise different aspects of the mapping from a cancer cells genotype and
environment to its phenotype. Our central premise is that cancer is an evolving
system subject to mutation and selection, and the primary conduit for these
processes to occur is the cancer cell whose behaviour is regulated on multiple
biological scales. The selection pressure is mainly driven by the
microenvironment that the tumour is growing in and this acts directly upon the
cell phenotype. In turn, the phenotype is driven by the intracellular pathways
that are regulated by the genotype. Integrating all of these processes is a
massive undertaking and requires bridging many biological scales (i.e.
genotype, pathway, phenotype and environment) that we will only scratch the
surface of in this review. We will focus on models that use neural networks as
a means of connecting these different biological scales, since they allow us to
easily create heterogeneity for selection to act upon and importantly this
heterogeneity can be implemented at different biological scales. More
specifically, we consider three different neural networks that bridge different
aspects of these scales and the dialogue with the micro-environment, (i) the
impact of the micro-environment on evolutionary dynamics, (ii) the mapping from
genotype to phenotype under drug-induced perturbations and (iii) pathway
activity in both normal and cancer cells under different micro-environmental
conditions
A Sequence-to-Function Map for Ribozyme-catalyzed Metabolisms
We introduce a novel genotype-phenotype mapping based on
the relation between RNA sequence and its secondary structure for the
use in evolutionary studies. Various extensive studies concerning RNA
folding in the context of neutral theory yielded insights about properties of the structure space and the mapping itself. We intend to get a
better understanding of some of these properties and especially of the
evolution of RNA-molecules as well as their effect on the evolution of the
entire molecular system. We investigate the constitution of the neutral
network and compare our mapping with other artificial approaches using
cellular automatons, random boolean networks and others also based on
RNA folding. We yield the highest extent, connectivity and evolvability
of the underlying neutral network. Further, we successfully apply the
mapping in an existing model for the evolution of a ribozyme-catalyzed
metabolism
A Method for the Perceptual Optimization of Complex Visualizations
A common problem in visualization applications is the display of one surface overlying another. Unfortunately, it is extremely difficult to do this clearly and effectively. Stereoscopic viewing can help, but in order for us to be able to see both surfaces simultaneously, they must be textured, and the top surface must be made partially transparent. There is also abundant evidence that all textures are not equal in helping to reveal surface shape, but there are no general guidelines describing the best set of textures to be used in this way. What makes the problem difficult to perceptually optimize is that there are a great many variables involved. Both foreground and background textures must be specified in terms of their component colors, texture element shapes, distributions, and sizes. Also to be specified is the degree of transparency for the foreground texture components. Here we report on a novel approach to creating perceptually optimal solutions to complex visualization problems and we apply it to the overlapping surface problem as a test case. Our approach is a three-stage process. In the first stage we create a parameterized method for specifying a foreground and background pair of textures. In the second stage a genetic algorithm is applied to a population of texture pairs using subject judgments as a selection criterion. Over many trials effective texture pairs evolve. The third stage involves characterizing and generalizing the examples of effective textures. We detail this process and present some early results
Lenia and Expanded Universe
We report experimental extensions of Lenia, a continuous cellular automata
family capable of producing lifelike self-organizing autonomous patterns. The
rule of Lenia was generalized into higher dimensions, multiple kernels, and
multiple channels. The final architecture approaches what can be seen as a
recurrent convolutional neural network. Using semi-automatic search e.g.
genetic algorithm, we discovered new phenomena like polyhedral symmetries,
individuality, self-replication, emission, growth by ingestion, and saw the
emergence of "virtual eukaryotes" that possess internal division of labor and
type differentiation. We discuss the results in the contexts of biology,
artificial life, and artificial intelligence.Comment: 8 pages, 5 figures, 1 table; submitted to ALIFE 2020 conferenc
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