Recent advances in experimental techniques to probe fast excited-state dynamics in biological molecules in the gas phase : dynamics in nucleotides, amino acids and beyond

In many chemical reactions, an activation barrier must be overcome before a chemical transformation can occur. As such, understanding the behaviour of molecules in energetically excited states is critical to understanding the chemical changes that these molecules undergo. Among the most prominent reactions for mankind to understand are chemical changes that occur in our own biological molecules. A notable example is the focus towards understanding the interaction of DNA with ultraviolet radiation and the subsequent chemical changes. However, the interaction of radiation with large biological structures is highly complex, and thus the photochemistry of these systems as a whole is poorly understood. Studying the gas-phase spectroscopy and ultrafast dynamics of the building blocks of these more complex biomolecules offers the tantalizing prospect of providing a scientifically intuitive bottom-up approach, beginning with the study of the subunits of large polymeric biomolecules and monitoring the evolution in photochemistry as the complexity of the molecules is increased. While highly attractive, one of the main challenges of this approach is in transferring large, and in many cases, thermally labile molecules into vacuum. This review discusses the recent advances in cutting-edge experimental methodologies, emerging as excellent candidates for progressing this bottom-up approach

Robots, drugs, reality and education: how the future will change how we think

Emerging technologies for learning report - Article exploring various future trends and their potential impact on educatio

Public Understanding of Carbon Sequestration in Australia: Socio-Demographic Predictors of Knowledge, Engagement and Trust

This article explores the extent to which socio-demographic characteristics influence knowledge, trust, risk perception and acceptance of an emerging scientific technology, carbon sequestration or carbon capture and storage (CCS), which is positioned as a solution to the greenhouse gas problem. An online survey of 1273 Australian adults highlights the general public’s lack of knowledge about CCS and willingness to engage and learn. Compared to men, women were less accepting of CCS and more concerned about safety, risk and effectiveness. Those with a higher education were more aware of the greenhouse gas debate and supportive of CCS, whilst younger Australians were more trusting of information providers to “tell the truth” about CCS. By identifying key attitudes, expectations and fears of specific sub-groups towards CCS, this research provides an initial basis for developing effective public policy and community engagement, risk communication and education strategies for this emerging technology in Australi

The non-use and influence of UK energy sector indicators

This paper presents the results from a case study on the role in policymaking of UK Energy Sector Indicators (ESIs), introduced by the government in 2003. The findings show that the ESIs constituted a very minor element within the broader evidence-base used by policymakers, and that this indicator set and its objectives were poorly known even to central players in the sector. The findings of this research provide further evidence for the observation that scientific knowledge (including evaluations, assessments and indicators) seldom play an instrumental role in policymaking, and are more likely to produce indirect, conceptual and political impacts. The analysis provides a number of tentative conclusions concerning such potential indirect impacts that accrue mainly through processes of dialogue and argumentation both during the preparation of the indicators and after their publication as part of the annual reporting by the UK energy department. The ESIs have played various conceptual and political roles, yet the concrete outcomes in terms of policy change remain to be explored. The conclusions highlight the limitations of rationalist notions of direct, instrumental use in the efforts to understand the role of indicators in policymaking. The paper concludes by three tentative propositions concerning the explanations to the absence of instrumental role of the ESIs, which could be usefully explored in future research: the characteristics of the energy sector; the characteristics of the UK policy culture; and the exceptionality of the ESIs in the general evidence-base of UK energy sector