342 research outputs found
An Interpretable Deep Hierarchical Semantic Convolutional Neural Network for Lung Nodule Malignancy Classification
While deep learning methods are increasingly being applied to tasks such as
computer-aided diagnosis, these models are difficult to interpret, do not
incorporate prior domain knowledge, and are often considered as a "black-box."
The lack of model interpretability hinders them from being fully understood by
target users such as radiologists. In this paper, we present a novel
interpretable deep hierarchical semantic convolutional neural network (HSCNN)
to predict whether a given pulmonary nodule observed on a computed tomography
(CT) scan is malignant. Our network provides two levels of output: 1) low-level
radiologist semantic features, and 2) a high-level malignancy prediction score.
The low-level semantic outputs quantify the diagnostic features used by
radiologists and serve to explain how the model interprets the images in an
expert-driven manner. The information from these low-level tasks, along with
the representations learned by the convolutional layers, are then combined and
used to infer the high-level task of predicting nodule malignancy. This unified
architecture is trained by optimizing a global loss function including both
low- and high-level tasks, thereby learning all the parameters within a joint
framework. Our experimental results using the Lung Image Database Consortium
(LIDC) show that the proposed method not only produces interpretable lung
cancer predictions but also achieves significantly better results compared to
common 3D CNN approaches
Explainable artificial intelligence (XAI) in deep learning-based medical image analysis
With an increase in deep learning-based methods, the call for explainability
of such methods grows, especially in high-stakes decision making areas such as
medical image analysis. This survey presents an overview of eXplainable
Artificial Intelligence (XAI) used in deep learning-based medical image
analysis. A framework of XAI criteria is introduced to classify deep
learning-based medical image analysis methods. Papers on XAI techniques in
medical image analysis are then surveyed and categorized according to the
framework and according to anatomical location. The paper concludes with an
outlook of future opportunities for XAI in medical image analysis.Comment: Submitted for publication. Comments welcome by email to first autho
Explainable deep learning models in medical image analysis
Deep learning methods have been very effective for a variety of medical
diagnostic tasks and has even beaten human experts on some of those. However,
the black-box nature of the algorithms has restricted clinical use. Recent
explainability studies aim to show the features that influence the decision of
a model the most. The majority of literature reviews of this area have focused
on taxonomy, ethics, and the need for explanations. A review of the current
applications of explainable deep learning for different medical imaging tasks
is presented here. The various approaches, challenges for clinical deployment,
and the areas requiring further research are discussed here from a practical
standpoint of a deep learning researcher designing a system for the clinical
end-users.Comment: Preprint submitted to J.Imaging, MDP
Invariant Scattering Transform for Medical Imaging
Over the years, the Invariant Scattering Transform (IST) technique has become
popular for medical image analysis, including using wavelet transform
computation using Convolutional Neural Networks (CNN) to capture patterns'
scale and orientation in the input signal. IST aims to be invariant to
transformations that are common in medical images, such as translation,
rotation, scaling, and deformation, used to improve the performance in medical
imaging applications such as segmentation, classification, and registration,
which can be integrated into machine learning algorithms for disease detection,
diagnosis, and treatment planning. Additionally, combining IST with deep
learning approaches has the potential to leverage their strengths and enhance
medical image analysis outcomes. This study provides an overview of IST in
medical imaging by considering the types of IST, their application,
limitations, and potential scopes for future researchers and practitioners
Improving diagnosis and prognosis of lung cancer using vision transformers: A scoping review
Vision transformer-based methods are advancing the field of medical
artificial intelligence and cancer imaging, including lung cancer applications.
Recently, many researchers have developed vision transformer-based AI methods
for lung cancer diagnosis and prognosis. This scoping review aims to identify
the recent developments on vision transformer-based AI methods for lung cancer
imaging applications. It provides key insights into how vision transformers
complemented the performance of AI and deep learning methods for lung cancer.
Furthermore, the review also identifies the datasets that contributed to
advancing the field. Of the 314 retrieved studies, this review included 34
studies published from 2020 to 2022. The most commonly addressed task in these
studies was the classification of lung cancer types, such as lung squamous cell
carcinoma versus lung adenocarcinoma, and identifying benign versus malignant
pulmonary nodules. Other applications included survival prediction of lung
cancer patients and segmentation of lungs. The studies lacked clear strategies
for clinical transformation. SWIN transformer was a popular choice of the
researchers; however, many other architectures were also reported where vision
transformer was combined with convolutional neural networks or UNet model. It
can be concluded that vision transformer-based models are increasingly in
popularity for developing AI methods for lung cancer applications. However,
their computational complexity and clinical relevance are important factors to
be considered for future research work. This review provides valuable insights
for researchers in the field of AI and healthcare to advance the
state-of-the-art in lung cancer diagnosis and prognosis. We provide an
interactive dashboard on lung-cancer.onrender.com/.Comment: submitted to BMC Medical Imaging journa
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