8 research outputs found
Evaluating Information Retrieval and Access Tasks
This open access book summarizes the first two decades of the NII Testbeds and Community for Information access Research (NTCIR). NTCIR is a series of evaluation forums run by a global team of researchers and hosted by the National Institute of Informatics (NII), Japan. The book is unique in that it discusses not just what was done at NTCIR, but also how it was done and the impact it has achieved. For example, in some chapters the reader sees the early seeds of what eventually grew to be the search engines that provide access to content on the World Wide Web, today’s smartphones that can tailor what they show to the needs of their owners, and the smart speakers that enrich our lives at home and on the move. We also get glimpses into how new search engines can be built for mathematical formulae, or for the digital record of a lived human life. Key to the success of the NTCIR endeavor was early recognition that information access research is an empirical discipline and that evaluation therefore lay at the core of the enterprise. Evaluation is thus at the heart of each chapter in this book. They show, for example, how the recognition that some documents are more important than others has shaped thinking about evaluation design. The thirty-three contributors to this volume speak for the many hundreds of researchers from dozens of countries around the world who together shaped NTCIR as organizers and participants. This book is suitable for researchers, practitioners, and students—anyone who wants to learn about past and present evaluation efforts in information retrieval, information access, and natural language processing, as well as those who want to participate in an evaluation task or even to design and organize one
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In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation.
Regulatory T cells (Tregs) have been shown to be critical in the balance between autoimmunity and tolerance and have been implicated in several human autoimmune diseases. However, the small number of Tregs in peripheral blood limits their therapeutic potential. Therefore, we developed a protocol that would allow for the expansion of Tregs while retaining their suppressive activity. We isolated CD4+CD25 hi cells from human peripheral blood and expanded them in vitro in the presence of anti-CD3 and anti-CD28 magnetic Xcyte Dynabeads and high concentrations of exogenous Interleukin (IL)-2. Tregs were effectively expanded up to 200-fold while maintaining surface expression of CD25 and other markers of Tregs: CD62L, HLA-DR, CCR6, and FOXP3. The expanded Tregs suppressed proliferation and cytokine secretion of responder PBMCs in co-cultures stimulated with anti-CD3 or alloantigen. Treg expansion is a critical first step before consideration of Tregs as a therapeutic intervention in patients with autoimmune or graft-versus-host disease
Shortest Route at Dynamic Location with Node Combination-Dijkstra Algorithm
Abstract— Online transportation has become a basic
requirement of the general public in support of all activities to go
to work, school or vacation to the sights. Public transportation
services compete to provide the best service so that consumers
feel comfortable using the services offered, so that all activities
are noticed, one of them is the search for the shortest route in
picking the buyer or delivering to the destination. Node
Combination method can minimize memory usage and this
methode is more optimal when compared to A* and Ant Colony
in the shortest route search like Dijkstra algorithm, but can’t
store the history node that has been passed. Therefore, using
node combination algorithm is very good in searching the
shortest distance is not the shortest route. This paper is
structured to modify the node combination algorithm to solve the
problem of finding the shortest route at the dynamic location
obtained from the transport fleet by displaying the nodes that
have the shortest distance and will be implemented in the
geographic information system in the form of map to facilitate
the use of the system.
Keywords— Shortest Path, Algorithm Dijkstra, Node
Combination, Dynamic Location (key words
Anales del XIII Congreso Argentino de Ciencias de la Computación (CACIC)
Contenido:
Arquitecturas de computadoras
Sistemas embebidos
Arquitecturas orientadas a servicios (SOA)
Redes de comunicaciones
Redes heterogéneas
Redes de Avanzada
Redes inalámbricas
Redes móviles
Redes activas
Administración y monitoreo de redes y servicios
Calidad de Servicio (QoS, SLAs)
Seguridad informática y autenticación, privacidad
Infraestructura para firma digital y certificados digitales
Análisis y detección de vulnerabilidades
Sistemas operativos
Sistemas P2P
Middleware
Infraestructura para grid
Servicios de integración (Web Services o .Net)Red de Universidades con Carreras en Informática (RedUNCI
Anales del XIII Congreso Argentino de Ciencias de la Computación (CACIC)
Contenido:
Arquitecturas de computadoras
Sistemas embebidos
Arquitecturas orientadas a servicios (SOA)
Redes de comunicaciones
Redes heterogéneas
Redes de Avanzada
Redes inalámbricas
Redes móviles
Redes activas
Administración y monitoreo de redes y servicios
Calidad de Servicio (QoS, SLAs)
Seguridad informática y autenticación, privacidad
Infraestructura para firma digital y certificados digitales
Análisis y detección de vulnerabilidades
Sistemas operativos
Sistemas P2P
Middleware
Infraestructura para grid
Servicios de integración (Web Services o .Net)Red de Universidades con Carreras en Informática (RedUNCI