THREE OLD KINGDOM FRAGMENTARY RELIEFS AND THEIR OWNERS

This paper aims to publish three fragments preserved in the archaeological store at Atfiyah and belong to three mastaba tombs at Giza; two of them were mostly collapsed. The importance of this paper is due to that two fragments of those in question only contain the names of their owners (the second and the third fragments), while the first one bears some titles without its owner name. Although two fragments bear the names of their owners, these names were frequently repeated in the Old Kingdom which makes it more difficult to determine their identity. So, identifying the persons who held these names is also the aim of this paper. Accordingly, this paper tries to find out the owners of those fragments and their tombs. After examining the names and the titles inscribed on these fragments and after reconstructing and supplementing the texts of the first fragment, the study concluded that the first fragment belongs to KA(⸗j)-xr-PtH:Ftk-tA of the Sixth Dynasty, and the owner of the mastaba tomb G 7652 in Giza, while the second fragment is one of the two stelae of anx 5pss-kA⸗f of the Fifth Dynasty, and the owner of the mastaba tomb G 6040 in Giza. The third fragment is a lintel of 1p-Hr-nfr, the wife of Prj-sn who lived during the middle of the Fifth Dynasty and the beginning of the Sixth Dynasty. This fragment may have been a part of his mastaba tomb LD 78 in Giza.تتهدف تلک الورقة البحثية إلى نشر ثلاثة قطع محفوظة بالمخزن الأثري في أطفيح، وتنتمي إلى بقايا ثلاثة مقابر تهدمت معظم أجزائها. وتکمن أهمية تلک الورقة البحثية في التعرف على أسماء أصحاب تلک القطع الثلاثة؛ حيث إن قطعتين فقط من تلک القطع الثلاثة تحمل أسماء مالکيها (القطعتين الثانية والثالثة)، بينما القطعة الأولى تحمل بقايا ألقاب بدون أي اسم يدل على صاحب تلک القطعة. وتزداد المشکلة أن تلک الأسماء تکرر ظهورها کثيرًا في الدولة القديمة. وبعد فحص الألقاب والأسماء التي وردت على تلک القطع وإعادة ترکيب واستکمال النصوص التي وردت على القطعة الأولى، فقد انتهت تلک الدراسة إلى أن القطعة الأولى تخص المدعو کا خر بتاح فتک تا من الأسرة السادسة، وصاحب المقبرة G 7652 بالجيزة، بينما القطعة الثانية هي لوحة مستديرة القمة من إحدى لوحتين لشخص يدعى عنخ شبسسکاف من الأسرة الخامسة، وصاحب المقبرة G 6040 بالجيزة، أما القطعة الثالثة فهي عبارة عن جزء من عتب يحمل اسم السيدة حتب حر نفرت زوجة المدعو بري سن ، الذي ربما عاش في الفترة ما بين منتصف الأسرة الخامسة وحتى بداية الأسرة السادسة وربما کانت تلک القطعة هي جزء من مقبرته في الجيزة رقم LD 78

A Study of Snippet Length and Informativeness: Behaviour, Performance and User Experience

The design and presentation of a Search Engine Results Page (SERP) has been subject to much research. With many contemporary aspects of the SERP now under scrutiny, work still remains in investigating more traditional SERP components, such as the result summary. Prior studies have examined a variety of different aspects of result summaries, but in this paper we investigate the influence of result summary length on search behaviour, performance and user experience. To this end, we designed and conducted a within-subjects experiment using the TREC AQUAINT news collection with 53 participants. Using Kullback-Leibler distance as a measure of information gain, we examined result summaries of different lengths and selected four conditions where the change in information gain was the greatest: (i) title only; (ii) title plus one snippet; (iii) title plus two snippets; and (iv) title plus four snippets. Findings show that participants broadly preferred longer result summaries, as they were perceived to be more informative. However, their performance in terms of correctly identifying relevant documents was similar across all four conditions. Furthermore, while the participants felt that longer summaries were more informative, empirical observations suggest otherwise; while participants were more likely to click on relevant items given longer summaries, they also were more likely to click on non-relevant items. This shows that longer is not necessarily better, though participants perceived that to be the case - and second, they reveal a positive relationship between the length and informativeness of summaries and their attractiveness (i.e. clickthrough rates). These findings show that there are tensions between perception and performance when designing result summaries that need to be taken into account

Unsupervised extraction of recurring words from infant-directed speech

To date, most computational models of infant word segmentation have worked from phonemic or phonetic input, or have used toy datasets. In this paper, we present an algorithm for word extraction that works directly from naturalistic acoustic input: infant-directed speech from the CHILDES corpus. The algorithm identifies recurring acoustic patterns that are candidates for identification as words or phrases, and then clusters together the most similar patterns. The recurring patterns are found in a single pass through the corpus using an incremental method, where only a small number of utterances are considered at once. Despite this limitation, we show that the algorithm is able to extract a number of recurring words, including some that infants learn earliest, such as Mommy and the child’s name. We also introduce a novel information-theoretic evaluation measure

Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal

Eukaryotic Okazaki fragment maturation requires complete removal of the initiating RNA primer before ligation occurs. Polymerase delta (Pol delta) extends the upstream Okazaki fragment and displaces the 5' end of the downstream primer into a single-nucleotide flap, which is removed by FEN1 nuclease cleavage. This process is repeated until all RNA is removed. However, a small fraction of flaps escapes cleavage and grows long enough to be coated with RPA and requires the consecutive action of the Dna2 and FEN1 nucleases for processing. Here we tested whether RPA inhibits FEN1 cleavage of long flaps as proposed. Surprisingly, we determined that RPA binding to long flaps made dynamically by Pol delta only slightly inhibited FEN1 cleavage, apparently obviating the need for Dna2. Therefore, we asked whether other relevant proteins promote long flap cleavage via the Dna2 pathway. The Pif1 helicase, implicated in Okazaki maturation from genetic studies, improved flap displacement and increased RPA inhibition of long flap cleavage by FEN1. These results suggest that Pif1 accelerates long flap growth, allowing RPA to bind before FEN1 can act, thereby inhibiting FEN1 cleavage. Therefore, Pif1 directs long flaps toward the two-nuclease pathway, requiring Dna2 cleavage for primer removal

Simplifying the mosaic description of DNA sequences

By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share compositional similarity with one or more distant (non--neighbouring) domains. We thus obtain a coarse--grained description of the given DNA string in terms of a smaller set of distinct domain labels. This yields a minimal domain description of a given DNA sequence, significantly reducing its organizational complexity. This procedure gives a new means of evaluating genomic complexity as one examines organisms ranging from bacteria to human. The mosaic organization of DNA sequences could have originated from the insertion of fragments of one genome (the parasite) inside another (the host), and we present numerical experiments that are suggestive of this scenario.Comment: 16 pages, 1 figure, Accepted for publication in Phys. Rev.

Near-optimal RNA-Seq quantification

We present a novel approach to RNA-Seq quantification that is near optimal in speed and accuracy. Software implementing the approach, called kallisto, can be used to analyze 30 million unaligned paired-end RNA-Seq reads in less than 5 minutes on a standard laptop computer while providing results as accurate as those of the best existing tools. This removes a major computational bottleneck in RNA-Seq analysis.Comment: - Added some results (paralog analysis, allele specific expression analysis, alignment comparison, accuracy analysis with TPMs) - Switched bootstrap analysis to human sample from SEQC-MAQCIII - Provided link to a snakefile that allows for reproducibility of all results and figures in the pape

Rapid evolution of the env gene leader sequence in cats naturally infected with feline immunodeficiency virus (FIV)

Analysing the evolution of FIV on the intra-host level is important, in order to address whether the diversity and composition of viral quasispecies affects disease progression.<p></p> We examined the intra-host diversity and the evolutionary rates of the entire env and structural fragments of the env sequences obtained from sequential blood samples in 43 naturally infected domestic cats that displayed different clinical outcomes. We observed in the majority of cats that FIV env showed very low levels of intra-host diversity. We estimated that env evolved at the rate of 1.16 x 10-3 substitutions per site per year and demonstrated that recombinant sequences evolved faster than non-recombinant sequences. It was evident that the V3-V5 fragment of FIV env displayed higher evolutionary rates in healthy cats than in those with terminal illness. Our study provided the first evidence that the leader sequence of env, rather than the V3-V5 sequence, had the highest intra-host diversity and the highest evolutionary rate of all env fragments, consistent with this region being under a strong selective pressure for genetic variation.<p></p> Overall, FIV env displayed relatively low intra-host diversity and evolved slowly in naturally infected cats. The maximal evolutionary rate was observed in the leader sequence of env. Although genetic stability is not necessarily a prerequisite for clinical stability, the higher genetic stability of FIV compared to HIV might explain why many naturally infected cats do not progress to AIDS rapidly.<p></p&gt

Correlations between the mechanical loss and atomic structure of amorphous TiO2-doped Ta2O5 coatings

<p>Highly reflective dielectric mirror coatings are critical components in a range of precision optics applications including frequency combs, optical atomic clocks, precision interferometry and ring laser gyroscopes. A key limitation to the performance in these applications is thermal noise, arising from the mechanical loss of the coatings. The origins of the mechanical loss from these coatings is not well understood.</p> <p>Recent work suggests that the mechanical loss of amorphous Ta2O5 coatings can drop by as much as 40% when it is doped with TiO2. We use a combination of electron diffraction data and atomic modelling using molecular dynamics to probe the atomic structure of these coatings, and examine the correlations between changes in the atomic structure and changes in the mechanical loss of these coatings. Our results show the first correlation between changes in the mechanical loss and experimentally measured changes in the atomic structure resulting from variations in the level of TiO2 doping in TiO2-doped Ta2O5 coatings, in that increased homogeneity at the nearest-neighbour level appears to correlate with reduced mechanical loss. It is demonstrated that subtle but measurable changes in the nearest-neighbour homogeneity in an amorphous material can correlate with significant changes in macroscopic properties.</p&gt

Heavy Residue Formation in 20 MeV/nucleon 197Au + 90Zr collisions

The yields and velocity distributions of heavy residues and fission fragments from the reaction of 20 MeV/nucleon 197Au + 90Zr have been measured using the MSU A1200 fragment separator. A bimodal distribution of residues is observed, with one group, resulting from peripheral collisions, having fragment mass numbers A=160-200, while the other group, resulting from ``hard'' collisions, has A=120-160. This latter group of residues can be distinguished from fission fragments by their lower velocities. A model combining deep-inelastic transfer and incomplete fusion for the primary interaction stage and a statistical evaporation code for the deexcitation stage has been used to describe the properties of the product distributions.Comment: 19 pages, 6 figures, preprint submitted to Nucl. Phys.