Microcalcification Detection Applying Artificial Neural Networks and Mathematical Morphology in Digital Mammograms

Breast cancer is one of the leading causes to women mortality in the world and early detection is an important means to reduce the mortality rate. The presence of microcalcifications clusters has been considered as a very important indicator of malignant types of breast cancer and its detection is important to prevent and treat the disease. This paper presents an alternative and effective approach in order to detect microcalcifications clusters in digitized mammograms based on the synergy of the image processing, pattern recognition and artificial intelligence. The mathematical morphology is an image processing technique used for the purpose of image enhancement. A k-means algorithm is used to cluster the data based on the features vectors and finally an artificial neural network-based classifier is applied and the classification performance is evaluated by a ROC curve. Experimental results indicate that the percentage of correct classification was 99.72%, obtaining 100% true positive (sensitivity) and 99.67% false positive (specificity), with the best classifier proposed. In case of the best classifier, we obtained a performance evaluation of classification of Az = 0.987

A New Approach for Clustered MCs Classification with Sparse Features Learning and TWSVM

In digital mammograms, an early sign of breast cancer is the existence of microcalcification clusters (MCs), which is very important to the early breast cancer detection. In this paper, a new approach is proposed to classify and detect MCs. We formulate this classification problem as sparse feature learning based classification on behalf of the test samples with a set of training samples, which are also known as a “vocabulary” of visual parts. A visual information-rich vocabulary of training samples is manually built up from a set of samples, which include MCs parts and no-MCs parts. With the prior ground truth of MCs in mammograms, the sparse feature learning is acquired by the lP-regularized least square approach with the interior-point method. Then we designed the sparse feature learning based MCs classification algorithm using twin support vector machines (TWSVMs). To investigate its performance, the proposed method is applied to DDSM datasets and compared with support vector machines (SVMs) with the same dataset. Experiments have shown that performance of the proposed method is more efficient or better than the state-of-art methods

Automated Analysis of Mammograms using Evolutionary Algorithms

Breast cancer is the leading cause of death in women in the western countries. The diagnosis of breast cancer at the earlier stage may be particularly important since it provides early treatment, this will decreases the chance of cancer spreading and increase the survival rates. The hard work is the early detection of any tissues abnormal and confirmation of their cancerous natures. In additionally, finding abnormal on very early stage can also affected by poor quality of image and other problems that might show on a mammogram. Mammograms are high resolution x-rays of the breast that are widely used to screen for cancer in women. This report describes the stages of development of a novel representation of Cartesian Genetic programming as part of a computer aided diagnosis system. Specifically, this work is concerned with automated recognition of microcalcifications, one of the key structures used to identify cancer. Results are presented for the application of the proposed algorithm to a number of mammogram sections taken from the Lawrence Livermore National Laboratory Database. The performance of any algorithm such as evolutionary algorithm is only good as the data it is trained on. More specifically, the class represented in the training data must consist of the true examples or else reliable classifications. Considering the difficulties in obtaining a previously constructed database, there is a new database has been construct to avoiding pitfalls and lead on the novel evolutional algorithm Multi-chromosome Cartesian genetic programming the success on classification of microcalcifications in mammograms

A Bottom-Up Review of Image Analysis Methods for Suspicious Region Detection in Mammograms.

Breast cancer is one of the most common death causes amongst women all over the world. Early detection of breast cancer plays a critical role in increasing the survival rate. Various imaging modalities, such as mammography, breast MRI, ultrasound and thermography, are used to detect breast cancer. Though there is a considerable success with mammography in biomedical imaging, detecting suspicious areas remains a challenge because, due to the manual examination and variations in shape, size, other mass morphological features, mammography accuracy changes with the density of the breast. Furthermore, going through the analysis of many mammograms per day can be a tedious task for radiologists and practitioners. One of the main objectives of biomedical imaging is to provide radiologists and practitioners with tools to help them identify all suspicious regions in a given image. Computer-aided mass detection in mammograms can serve as a second opinion tool to help radiologists avoid running into oversight errors. The scientific community has made much progress in this topic, and several approaches have been proposed along the way. Following a bottom-up narrative, this paper surveys different scientific methodologies and techniques to detect suspicious regions in mammograms spanning from methods based on low-level image features to the most recent novelties in AI-based approaches. Both theoretical and practical grounds are provided across the paper sections to highlight the pros and cons of different methodologies. The paper's main scope is to let readers embark on a journey through a fully comprehensive description of techniques, strategies and datasets on the topic

Analysis of Mammographic Images for Early Detection of Breast Cancer Using Machine Learning Techniques

Breast cancer is the main reason for death among women. Radiographic images obtained from mammography equipment are one of the most frequently used techniques for helping in early detection of breast cancer. The motivation behind this study is to focus the tumour types of breast cancer images .It is methodology to anticipated a sickness in view of the visual conclusion of breast disease tumour types with precision, particularly when numerous feature are related. Breast Cancer (BC) is one such sample where the phenomenon is very complex furthermore numerous feature of tumour types are included. In the present investigation, various pattern recognition techniques were used for the classification of breast cancer using mammograms image processing techniques .The pattern recognition techniques for tumour image enhancements, segmentation, texture based image feature extraction and subsequent classification of breast cancer mammogram image was successfully performed. When two machine learning techniques such as Artificial Neural Network (ANN), Support Vector Machine (SVM) were used to classify 120 images, it was observed from the results that Artificial Neural Network classifiers demonstrated the h classification rate 91.31% and the SVM with both Radial Basis Function (RBF) and linear kernel classifiers demonstrated the highest classification rate of 92.11% and RBF classification rate is 92.85%

Analysis of Mammographic Images for Early Detection of Breast Cancer Using Machine Learning Techniques

Breast cancer is the main reason for death among women. Radiographic images obtained from mammography equipment are one of the most frequently used techniques for helping in early detection of breast cancer. The motivation behind this study is to focus the tumour types of breast cancer images .It is methodology to anticipated a sickness in view of the visual conclusion of breast disease tumour types with precision, particularly when numerous feature are related. Breast Cancer (BC) is one such sample where the phenomenon is very complex furthermore numerous feature of tumour types are included. In the present investigation, various pattern recognition techniques were used for the classification of breast cancer using mammograms image processing techniques .The pattern recognition techniques for tumour image enhancements, segmentation, texture based image feature extraction and subsequent classification of breast cancer mammogram image was successfully performed. When two machine learning techniques such as Artificial Neural Network (ANN), Support Vector Machine (SVM) were used to classify 120 images, it was observed from the results that Artificial Neural Network classifiers demonstrated the h classification rate 91.31% and the SVM with both Radial Basis Function (RBF) and linear kernel classifiers demonstrated the highest classification rate of 92.11% and RBF classification rate is 92.85%