Synchronization of inertial memristive neural networks with time-varying delays via static or dynamic event-triggered control

Funding Information: This work was supported in part by the National Natural Science Foundation of China under Grant 61971185, the Major Research Project of the National Natural Science Foundation of China under Grant 91964108 and the Open Fund Project of Key Laboratory in Hunan Universities under Grant 18K010. Publisher Copyright: © 2020 Elsevier B.V.This paper investigates the synchronization problem of inertial memristive neural networks (IMNNs) with time-varying delays via event-triggered control (ETC) scheme and state feedback controller for the first time. First, two types of state feedback controllers are designed; the first type of controller is added to the transformational first-order system, and the second type of controller is added to the original second-order system. Next, based on each feedback controller, static event-triggered control (SETC) condition and dynamic event-triggered control (DETC) condition are presented to significantly reduce the update times of controller and decrease the computing cost. Then, some sufficient conditions are given such that synchronization of IMNNs with time-varying delays can be achieved under ETC schemes. Finally, a numerical simulation and some data analyses are given to verify the validity of the proposed results.Peer reviewe

Genetic noise control via protein oligomerization

Gene expression in a cell entails random reaction events occurring over disparate time scales. Thus, molecular noise that often results in phenotypic and population-dynamic consequences sets a fundamental limit to biochemical signaling. While there have been numerous studies correlating the architecture of cellular reaction networks with noise tolerance, only a limited effort has been made to understand the dynamic role of protein-protein interactions. Here we have developed a fully stochastic model for the positive feedback control of a single gene, as well as a pair of genes (toggle switch), integrating quantitative results from previous in vivo and in vitro studies. We find that the overall noise-level is reduced and the frequency content of the noise is dramatically shifted to the physiologically irrelevant high-frequency regime in the presence of protein dimerization. This is independent of the choice of monomer or dimer as transcription factor and persists throughout the multiple model topologies considered. For the toggle switch, we additionally find that the presence of a protein dimer, either homodimer or heterodimer, may significantly reduce its random switching rate. Hence, the dimer promotes the robust function of bistable switches by preventing the uninduced (induced) state from randomly being induced (uninduced). The specific binding between regulatory proteins provides a buffer that may prevent the propagation of fluctuations in genetic activity. The capacity of the buffer is a non-monotonic function of association-dissociation rates. Since the protein oligomerization per se does not require extra protein components to be expressed, it provides a basis for the rapid control of intrinsic or extrinsic noise

Modeling Supply Networks and Business Cycles as Unstable Transport Phenomena

Physical concepts developed to describe instabilities in traffic flows can be generalized in a way that allows one to understand the well-known instability of supply chains (the so-called ``bullwhip effect''). That is, small variations in the consumption rate can cause large variations in the production rate of companies generating the requested product. Interestingly, the resulting oscillations have characteristic frequencies which are considerably lower than the variations in the consumption rate. This suggests that instabilities of supply chains may be the reason for the existence of business cycles. At the same time, we establish some link to queuing theory and between micro- and macroeconomics.Comment: For related work see http://www.helbing.or