2,336,652 research outputs found

    An informational approach to the global optimization of expensive-to-evaluate functions

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    In many global optimization problems motivated by engineering applications, the number of function evaluations is severely limited by time or cost. To ensure that each evaluation contributes to the localization of good candidates for the role of global minimizer, a sequential choice of evaluation points is usually carried out. In particular, when Kriging is used to interpolate past evaluations, the uncertainty associated with the lack of information on the function can be expressed and used to compute a number of criteria accounting for the interest of an additional evaluation at any given point. This paper introduces minimizer entropy as a new Kriging-based criterion for the sequential choice of points at which the function should be evaluated. Based on \emph{stepwise uncertainty reduction}, it accounts for the informational gain on the minimizer expected from a new evaluation. The criterion is approximated using conditional simulations of the Gaussian process model behind Kriging, and then inserted into an algorithm similar in spirit to the \emph{Efficient Global Optimization} (EGO) algorithm. An empirical comparison is carried out between our criterion and \emph{expected improvement}, one of the reference criteria in the literature. Experimental results indicate major evaluation savings over EGO. Finally, the method, which we call IAGO (for Informational Approach to Global Optimization) is extended to robust optimization problems, where both the factors to be tuned and the function evaluations are corrupted by noise.Comment: Accepted for publication in the Journal of Global Optimization (This is the revised version, with additional details on computational problems, and some grammatical changes

    Exploring the Issues: An Evaluation Literature Review

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    Finding ways to make evaluation more meaningful and more useful has been a key theme in the evaluation literature since the discipline began, and there is no shortage of discussion around improving evaluation among nonprofit practitioners. The topic has been a highlight at ONN's annual conference in recent years.However, much of the discussion around improving evaluation focuses on methodology, tools, and indicators.There has been less attention paid to who is asking and determining the questions of evaluation, such as who evaluation is for and what is its purpose. Consequently, the purpose of this background paper is to review the literature on evaluation use with a particular focus on systemic factors. In other words, we are interested in looking at the relationship between evaluation practice and the overall structure and function of the nonprofit sector in Ontario.We're interested in the policies and regulations that guide us, the roles played by various actors, theassumptions we make, the language we use, and the ways in which resources move through the sector. We're examining the purposes that evaluation serves, both overt and implicit. We want to learn more about the factors that make evaluations really useful, the issues that can get in the way of evaluations being useful, and ideas for improvement. Ultimately, our goal in this paper is to generate a broad vision to inform our project's final outcomes

    Charge and spin correlations of a one dimensional electron gas on the continuum

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    We present a variational Monte Carlo study of a model one dimensional electron gas on the continuum, with long-range interaction (1/r decay). At low density the reduced dimensionality brings about pseudonodes of the many-body wavefunction, yielding non-ergodic behavior of naive Monte Carlo sampling, which affects the evaluation of pair correlations and the related structure factors. The problem is however easily solved and we are able to carefully analyze the structure factors obtained from an optimal trial function, finding good agreement with the exact predictions for a Luttinger-like hamiltonian with an interaction similar to the one used in the present study.Comment: 4 pages, 3 figure

    Design considerations in a clinical trial of a cognitive behavioural intervention for the management of low back pain in primary care : Back Skills Training Trial

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    Background Low back pain (LBP) is a major public health problem. Risk factors for the development and persistence of LBP include physical and psychological factors. However, most research activity has focused on physical solutions including manipulation, exercise training and activity promotion. Methods/Design This randomised controlled trial will establish the clinical and cost-effectiveness of a group programme, based on cognitive behavioural principles, for the management of sub-acute and chronic LBP in primary care. Our primary outcomes are disease specific measures of pain and function. Secondary outcomes include back beliefs, generic health related quality of life and resource use. All outcomes are measured over 12 months. Participants randomised to the intervention arm are invited to attend up to six weekly sessions each of 90 minutes; each group has 6–8 participants. A parallel qualitative study will aid the evaluation of the intervention. Discussion In this paper we describe the rationale and design of a randomised evaluation of a group based cognitive behavioural intervention for low back pain

    Counting loop diagrams: computational complexity of higher-order amplitude evaluation

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    We discuss the computational complexity of the perturbative evaluation of scattering amplitudes, both by the Caravaglios-Moretti algorithm and by direct evaluation of the individual diagrams. For a self-interacting scalar theory, we determine the complexity as a function of the number of external legs. We describe a method for obtaining the number of topologically inequivalent Feynman graphs containing closed loops, and apply this to one- and two-loop amplitudes. We also compute the number of graphs weighted by their symmetry factors, thus arriving at exact and asymptotic estimates for the average symmetry factor of diagrams. We present results for the asymptotic number of diagrams up to 10 loops, and prove that the average symmetry factor approaches unity as the number of external legs becomes large.Comment: 27 pages, 17 table

    Relationship of cognitive function in patients with schizophrenia in remission to disability: a cross-sectional study in an Indian sample

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    Background: Cognitive deficits in various domains have been consistently replicated in patients with schizophrenia. Most studies looking at the relationship between cognitive dysfunction and functional disability are from developed countries. Studies from developing countries are few. The purpose of the present study was to compare the neurocognitive function in patients with schizophrenia who were in remission with that of normal controls and to determine if there is a relationship between measures of cognition and functional disability. <p/>Methods: This study was conducted in the Psychiatric Unit of a General Hospital in Mumbai, India. Cognitive function in 25 patients with schizophrenia in remission was compared to 25 normal controls. Remission was confirmed using the brief psychiatric rating scale (BPRS) and scale for the assessment of negative symptoms (SANS). Subjects were administered a battery of cognitive tests covering aspects of memory, executive function and attention. The results obtained were compared between the groups. Correlation analysis was used to look for relationship between illness factors, cognitive function and disability measured using the Indian disability evaluation and assessment scale. <p/>Results: Patients with schizophrenia showed significant deficits on tests of attention, concentration, verbal and visual memory and tests of frontal lobe/executive function. They fared worse on almost all the tests administered compared to normal controls. No relationship was found between age, duration of illness, number of years of education and cognitive function. In addition, we did not find a statistically significant relationship between cognitive function and scores on the disability scale. <p/>Conclusion: The data suggests that persistent cognitive deficits are seen in patients with schizophrenia under remission. The cognitive deficits were not associated with symptomatology and functional disability. It is possible that various factors such as employment and family support reduce disability due to schizophrenia in developing countries like India. Further studies from developing countries are required to explore the relationship between cognitive deficits, functional outcome and the role of socio-cultural variables as protective factors
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