Epilepsy

With the vision of including authors from different parts of the world, different educational backgrounds, and offering open-access to their published work, InTech proudly presents the latest edited book in epilepsy research, Epilepsy: Histological, electroencephalographic, and psychological aspects. Here are twelve interesting and inspiring chapters dealing with basic molecular and cellular mechanisms underlying epileptic seizures, electroencephalographic findings, and neuropsychological, psychological, and psychiatric aspects of epileptic seizures, but non-epileptic as well

Reservoir Computing: computation with dynamical systems

In het onderzoeksgebied Machine Learning worden systemen onderzocht die kunnen leren op basis van voorbeelden. Binnen dit onderzoeksgebied zijn de recurrente neurale netwerken een belangrijke deelgroep. Deze netwerken zijn abstracte modellen van de werking van delen van de hersenen. Zij zijn in staat om zeer complexe temporele problemen op te lossen maar zijn over het algemeen zeer moeilijk om te trainen. Recentelijk zijn een aantal gelijkaardige methodes voorgesteld die dit trainingsprobleem elimineren. Deze methodes worden aangeduid met de naam Reservoir Computing. Reservoir Computing combineert de indrukwekkende rekenkracht van recurrente neurale netwerken met een eenvoudige trainingsmethode. Bovendien blijkt dat deze trainingsmethoden niet beperkt zijn tot neurale netwerken, maar kunnen toegepast worden op generieke dynamische systemen. Waarom deze systemen goed werken en welke eigenschappen bepalend zijn voor de prestatie is evenwel nog niet duidelijk. Voor dit proefschrift is onderzoek gedaan naar de dynamische eigenschappen van generieke Reservoir Computing systemen. Zo is experimenteel aangetoond dat de idee van Reservoir Computing ook toepasbaar is op niet-neurale netwerken van dynamische knopen. Verder is een maat voorgesteld die gebruikt kan worden om het dynamisch regime van een reservoir te meten. Tenslotte is een adaptatieregel geïntroduceerd die voor een breed scala reservoirtypes de dynamica van het reservoir kan afregelen tot het gewenste dynamisch regime. De technieken beschreven in dit proefschrift zijn gedemonstreerd op verschillende academische en ingenieurstoepassingen

Progress Report No. 17

Progress report of the Biomedical Computer Laboratory, covering period 1 July 1980 to 30 June 1981

Technology 2002: the Third National Technology Transfer Conference and Exposition, Volume 1

The proceedings from the conference are presented. The topics covered include the following: computer technology, advanced manufacturing, materials science, biotechnology, and electronics

Models and Analysis of Vocal Emissions for Biomedical Applications

The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the neonate to the adult and elderly. Over the years the initial issues have grown and spread also in other aspects of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years always in Firenze, Italy. This edition celebrates twenty years of uninterrupted and succesfully research in the field of voice analysis

Non-invasive wearable sensing systems for continuous health monitoring and long-term behavior modeling

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2006.Includes bibliographical references (p. 212-228).Deploying new healthcare technologies for proactive health and elder care will become a major priority over the next decade, as medical care systems worldwide become strained by the aging populations. This thesis presents LiveNet, a distributed mobile system based on low-cost commodity hardware that can be deployed for a variety of healthcare applications. LiveNet embodies a flexible infrastructure platform intended for long-term ambulatory health monitoring with real-time data streaming and context classification capabilities. Using LiveNet, we are able to continuously monitor a wide range of physiological signals together with the user's activity and context, to develop a personalized, data-rich health profile of a user over time. Most clinical sensing technologies that exist have focused on accuracy and reliability, at the expense of cost-effectiveness, burden on the patient, and portability. Future proactive health technologies, on the other hand, must be affordable, unobtrusive, and non-invasive if the general population is going to adopt them.(cont.) In this thesis, we focus on the potential of using features derived from minimally invasive physiological and contextual sensors such as motion, speech, heart rate, skin conductance, and temperature/heat flux that can be used in combination with mobile technology to create powerful context-aware systems that are transparent to the user. In many cases, these non-invasive sensing technologies can completely replace more invasive diagnostic sensing for applications in long-term monitoring, behavior and physiology trending, and real-time proactive feedback and alert systems. Non-invasive sensing technologies are particularly important in ambulatory and continuous monitoring applications, where more cumbersome sensing equipment that is typically found in medical and clinical research settings is not usable. The research in this thesis demonstrates that it is possible to use simple non-invasive physiological and contextual sensing using the LiveNet system to accurately classify a variety of physiological conditions. We demonstrate that non-invasive sensing can be correlated to a variety of important physiological and behavioral phenomenon, and thus can serve as substitutes to more invasive and unwieldy forms of medical monitoring devices while still providing a high level of diagnostic power.(cont.) From this foundation, the LiveNet system is deployed in a number of studies to quantify physiological and contextual state. First, a number of classifiers for important health and general contextual cues such as activity state and stress level are developed from basic non-invasive physiological sensing. We then demonstrate that the LiveNet system can be used to develop systems that can classify clinically significant physiological and pathological conditions and that are robust in the presence of noise, motion artifacts, and other adverse conditions found in real-world situations. This is highlighted in a cold exposure and core body temperature study in collaboration with the U.S. Army Research Institute of Environmental Medicine. In this study, we show that it is possible to develop real-time implementations of these classifiers for proactive health monitors that can provide instantaneous feedback relevant in soldier monitoring applications. This thesis also demonstrates that the LiveNet platform can be used for long-term continuous monitoring applications to study physiological trends that vary slowly with time.(cont.) In a clinical study with the Psychiatry Department at the Massachusetts General Hospital, the LiveNet platform is used to continuously monitor clinically depressed patients during their stays on an in-patient ward for treatment. We show that we can accurately correlate physiology and behavior to depression state, as well as to track changes in depression state over time through the course of treatment. This study demonstrates how long-term physiology and behavioral changes can be captured to objectively measure medical treatment and medication efficacy. In another long-term monitoring study, the LiveNet platform is used to collect data on people's everyday behavior as they go through daily life. By collecting long-term behavioral data, we demonstrate the possibility of modeling and predicting high-level behavior using simple physiologic and contextual information derived solely from ambulatory mobile sensing technology.by Michael Sung.Ph.D

Progress Report No. 16

Progress report of the Biomedical Computer Laboratory, covering period 1 July 1979 to 30 June 1980

Publications of the Jet Propulsion Laboratory - July through December 1970

Bibliography of technical literature resulting from aerospace research and development at Jet Propulsion Laboratorie

Brains in dialogue: investigating accommodation in live conversational speech for both speech and EEG data.

One of the phenomena to emerge from the study of human spoken interaction is accommodation or the tendency of an individual’s speech patterning to shift relative to their interlocutor. Whilst the experimental approach to the detection of accommodation has a solid background in the literature, it tends to treat the process of accommodation as a black box. The general approach for the detection of accommodation in speech has been to record the speech of a given speaker prior to interaction and then again after an interaction. These two measures are then compared to the speech of the interlocutor to test for similarity. If the speech sample following interaction is more similar then we can say that accommodation has taken place. Part of the goal of this thesis is to evaluate whether it is possible to look into the black box of speech accommodation and measure it ‘in situ’. Given that speech accommodation appears to take place as a result of interaction, it would be reasonable to assume that a similar effect might be observable in other areas contributing to a communicative interaction. The notion of an interacting dyad developing an increased degree of alignment over the course of an interaction has been proposed by psychologists. Theories have posited that alignment occurs at multiple levels of engagement, from broad levels of syntactic alignment down to phonetic levels of alignment. The use of speech accommodation as an anchor with which to track the evolution of change in the brain signal may prove to be one approach to investigating the claims made by these theories. The second part of this thesis aims to evaluate whether the phenomenon of accommodation is also observable in the form of electrical signals generated by the brain, measured using Electroencephalography (EEG). However, evaluating the change in the EEG signal over a continuous stretch of time is a hurdle that will need to be tackled. Traditionally, EEG methodologies involve averaging the signal over many repetitions of the same task. This is not a viable option when investigating communicative interaction. Clearly the evaluation of accommodation in both speech and brain activity, especially for continuously unfolding phenomena such as accommodation, is a non-trivial task. In order to tackle this, an approach from speech recognition and computer science has been employed. The implementation of Hidden Markov Models (HMM) has been used to develop speech recognition systems and has also been used to detect fraudulent attempts to imitate the voice of others. Given that HMMs have successfully been employed to detect the imitation of another person’s speech they are a good candidate for being able to detect the movement towards or away from an interlocutor during the course of an interaction. In addition, the use of HMMs is non-domain specific, they can be used to evaluate any time-variant signal. This adaptability of the approach allows for it to also be applied to EEG signals in conjunction with the speech signal. Two experiments are presented here. The behavioural experiment aims to evaluate the ability of a HMM based approach to detect accommodation by engaging pairs of female, Glaswegian speakers in the collaborative DiapixUK task. The results of their interactions are then evaluated from both a traditional phonetic standpoint, by assessing changes in Voice Onset Time (VOT) of stop consonants, formant values of vowels and speech rate over the course of an interaction and using the HMM based approach. The neural experiment looks to evaluate the ability of a HMM based approach to detect accommodation in both the speech signal and in brain activity. The same experiment that was performed in Experiment 1 was repeated, with the addition of EEG caps to both participants. The data was then evaluated using the HMM based approach. This thesis presents findings that suggest a function for speech accommodation that has not been explored in the past. This is done through the use of a novel, HMM based, holistic acoustic-phonetic measurement tool which produced consistent measures across both experiments. Further to this, the measurement tool is shown to have possible extended uses for EEG data. The use of the presented HMM based, holistic-acoustic measurement tool presents a novel contribution to the field for the measurement and evaluation of accommodation

Tematski zbornik radova međunarodnog značaja. Tom 3 / Međunarodni naučni skup “Dani Arčibalda Rajsa”, Beograd, 3-4. mart 2015.

In front of you is the Thematic Collection of Papers presented at the International Scientific Confer-ence “Archibald Reiss Days”, which was organized by the Academy of Criminalistic and Police Studies in Belgrade, in co-operation with the Ministry of Interior and the Ministry of Education, Science and Techno-logical Development of the Republic of Serbia, National Police University of China, Lviv State University of Internal Affairs, Volgograd Academy of the Russian Internal Affairs Ministry, Faculty of Security in Skopje, Faculty of Criminal Justice and Security in Ljubljana, Police Academy “Alexandru Ioan Cuza“ in Bucharest, Academy of Police Force in Bratislava and Police College in Banjaluka, and held at the Academy of Crimi-nalistic and Police Studies, on 3 and 4 March 2015.International Scientific Conference “Archibald Reiss Days” is organized for the fifth time in a row, in memory of the founder and director of the first modern higher police school in Serbia, Rodolphe Archibald Reiss, PhD, after whom the Conference was named.The Thematic Collection of Papers contains 168 papers written by eminent scholars in the field of law, security, criminalistics, police studies, forensics, informatics, as well as members of national security system participating in education of the police, army and other security services from Spain, Russia, Ukraine, Bela-rus, China, Poland, Armenia, Portugal, Turkey, Austria, Slovakia, Hungary, Slovenia, Macedonia, Croatia, Montenegro, Bosnia and Herzegovina, Republic of Srpska and Serbia. Each paper has been reviewed by two reviewers, international experts competent for the field to which the paper is related, and the Thematic Conference Proceedings in whole has been reviewed by five competent international reviewers.The papers published in the Thematic Collection of Papers contain the overview of contemporary trends in the development of police education system, development of the police and contemporary secu-rity, criminalistic and forensic concepts. Furthermore, they provide us with the analysis of the rule of law activities in crime suppression, situation and trends in the above-mentioned fields, as well as suggestions on how to systematically deal with these issues. The Collection of Papers represents a significant contribution to the existing fund of scientific and expert knowledge in the field of criminalistic, security, penal and legal theory and practice. Publication of this Collection contributes to improving of mutual cooperation between educational, scientific and expert institutions at national, regional and international level