Non-invasive algorithm for bowel motility estimation using a back-propagation neural network model of bowel sounds

<p>Abstract</p> <p>Background</p> <p>Radiological scoring methods such as colon transit time (CTT) have been widely used for the assessment of bowel motility. However, these radiograph-based methods need cumbersome radiological instruments and their frequent exposure to radiation. Therefore, a non-invasive estimation algorithm of bowel motility, based on a back-propagation neural network (BPNN) model of bowel sounds (BS) obtained by an auscultation, was devised.</p> <p>Methods</p> <p>Twelve healthy males (age: 24.8 ± 2.7 years) and 6 patients with spinal cord injury (6 males, age: 55.3 ± 7.1 years) were examined. BS signals generated during the digestive process were recorded from 3 colonic segments (ascending, descending and sigmoid colon), and then, the acoustical features (jitter and shimmer) of the individual BS segment were obtained. Only 6 features (<it>J_{1, 3}, J_{3, 3}, S_{1, 2}, S_{2, 1}, S_{2, 2}, S_{3, 2}</it>), which are highly correlated to the CTTs measured by the conventional method, were used as the features of the input vector for the BPNN.</p> <p>Results</p> <p>As a results, both the jitters and shimmers of the normal subjects were relatively higher than those of the patients, whereas the CTTs of the normal subjects were relatively lower than those of the patients (<it>p </it>< 0.01). Also, through <it>k</it>-fold cross validation, the correlation coefficient and mean average error between the CTTs measured by a conventional radiograph and the values estimated by our algorithm were 0.89 and 10.6 hours, respectively.</p> <p>Conclusions</p> <p>The jitter and shimmer of the BS signals generated during the peristalsis could be clinically useful for the discriminative parameters of bowel motility. Also, the devised algorithm showed good potential for the continuous monitoring and estimation of bowel motility, instead of conventional radiography, and thus, it could be used as a complementary tool for the non-invasive measurement of bowel motility.</p

Audio Event Classification for Urban Soundscape Analysis

The study of urban soundscapes has gained momentum in recent years as more people become concerned with the level of noise around them and the negative impact this can have on comfort. Monitoring the sounds present in a sonic environment can be a laborious and time–consuming process if performed manually. Therefore, techniques for automated signal identification are gaining importance if soundscapes are to be objectively monitored. This thesis presents a novel approach to feature extraction for the purpose of classifying urban audio events, adding to the library of techniques already established in the field. The research explores how techniques with their origins in the encoding of speech signals can be adapted to represent the complex everyday sounds all around us to allow accurate classification. The analysis methods developed herein are based on the zero–crossings information contained within a signal. Originally developed for the classification of bioacoustic signals, the codebook of Time–Domain Signal Coding (TDSC) has its band–limited restrictions removed to become more generic. Classification using features extracted with the new codebook achieves accuracies of over 80% when combined with a Multilayer Perceptron classifier. Further advancements are made to the standard TDSC algorithm, drawing inspiration from wavelets, resulting in a novel dyadic representation of time–domain features. Carrying the label of Multiscale TDSC (MTDSC), classification accuracies of 70% are achieved using these features. Recommendations for further work focus on expanding the library of training data to improve the accuracy of the classification system. Further research into classifier design is also suggested

Deep Brain Stimulation (DBS) Applications

The issue is dedicated to applications of Deep Brain Stimulation and, in this issue, we would like to highlight the new developments that are taking place in the field. These include the application of new technology to existing indications, as well as ‘new’ indications. We would also like to highlight the most recent clinical evidence from international multicentre trials. The issue will include articles relating to movement disorders, pain, psychiatric indications, as well as emerging indications that are not yet accompanied by clinical evidence. We look forward to your expert contribution to this exciting issue