肘関節粘弾性特性分析に基づいた可変粘弾性握手マニピュレータの開発

【学位授与の要件】中央大学学位規則第4条第1項【論文審査委員主査】中村　太郎　（中央大学理工学部教授）【論文審査委員副査】平岡　弘之（中央大学理工学部教授）、新妻　実保子（中央大学理工学部准教授）、諸麥　俊司（中央大学理工学部准教授）、万　偉偉（大阪大学准教授）博士(工学)中央大

Bio-inspired robotic joint and manipulator : from biomechanical experimentation and modeling to human-like compliant finger design and control

textOne of the greatest challenges in controlling robotic hands is grasping and manipulating objects in unstructured and uncertain environments. Robotic hands are typically too rigid to react against unexpected impacts and disturbances in order to prevent damage. The human hands have great versatility and robustness due, in part, to the passive compliance and damping. Designing mechanical elements that are inspired by the nonlinear joint compliance of human hands is a promising solution to achieve human-like grasping and manipulation. However, the exact role of biomechanical elements in realizing joint stiffness is unknown. We conducted a series of experiments to investigate nonlinear stiffness and damping of the metacarpophalangeal (MCP) joint at the index finger. We designed a custom-made mechanism to integrate electromyography sensors (EMGs) and a motion capture system to collect data from 19 subjects. We investigated the relative contributions of muscle-tendon units and the MCP capsule ligament complex to joint stiffness with subject-specific modeling. The results show that the muscle-tendon units provide limited contribution to the passive joint compliance. This findings indicate that the parallel compliance, in the form of the capsule-ligament complex, is significant in defining the passive properties of the hand. To identify the passive damping, we used the hysteresis loops to investigate the energy dissipation function. We used symbolic regression and principal component analysis to derive and interpret the damping models. The results show that the nonlinear viscous damping depends on the cyclic frequency, and fluid and structural types of damping also exist at the MCP joint. Inspired by the nonlinear stiffness of the MCP joint, we developed a miniaturized mechanism that uses pouring liquid plastic to design energy storing elements. The key innovations in this design are: a) a set of nonlinear elasticity of compliant materials, b) variable pulley configurations to tune the stiffness profile, and c) pretension mechanism to scale the stiffness profile. The design exhibits human-like passive compliance. By taking advantage of miniaturized joint size and additive manufacturing, we incorporated the novel joint design in a novel robotic manipulator with six series elastic actuators (SEA). The robotic manipulator has passive joint compliance with the intrinsic property of human hands. To validate the system, we investigated the Cartesian stiffness of grasping with low-level force control. The results show that that the overall system performs a great force tracking with position feedback. The parallel compliance decreases the motor efforts and can stabilize the system.Mechanical Engineerin

Musculoskeletal Modeling of the Human Lower Limb Stiffness for Robotic Applications

This research work presents a physiologically accurate and novel computationally fast neuromusculoskeletal model of the human lower limb stiffness. The proposed computational framework uses electromyographic signals, motion capture data and ground reaction forces to predict the force developed by 43 musculotendon actuators. The estimated forces are then used to compute the musculotendon stiffness and the corresponding joint stiffness. The estimations at each musculotendon unit is constrained to simultaneously satisfy the joint angles and the joint moments of force generated with respect to five degrees of freedom, including: Hip Adduction-Abduction, Hip Flexion-Extension, Hip Internal-External Rotation, Knee Flexion-Extension, and Ankle Plantar-Dorsi Flexion. Advanced methods are used to perform accurate muscle-driven dynamic simulations and to guarantee the dynamic consistency between kinematic and kinetic data. This study presents also the design, simulation and prototyping of a small musculoskeletal humanoid made for replicating the human musculoskeletal structure in an artificial apparatus capable to maintain a quiet standing position using only a completely passive elastic actuation structure. The proposed prototype has a total mass of about 2 kg and its height is 40 cm. It comprises of four segments for each leg and six degrees of freedom, including: Hip Adduction-Abduction, Hip Flexion-Extension, Knee Flexion-Extension, Ankle Plantar-Dorsi Flexion, Ankle Inversion-Eversion, and Toe Flexion-Extension. In order to reconstruct the continuous state space parameters proper of the assembly's control of quiet standing, a hybrid non-linear Extended Kalman Filter based technique is proposed to combine a base-excited inverted pendulum kinematic model of the robot with the discrete-time position measurements. This research work provides effective solutions and readily available software tools to improve the human interaction with robotic assistive devices, advancing the research in neuromusculoskeletal modeling to better understand the mechanisms of actuation provided by human muscles and the rules that govern the lower limb joint stiffness regulation. The obtained results suggest that the neuromusculoskeletal modeling technology can be exploited to address the challenges on the development of musculoskeletal humanoids, new generation human-robot interfaces, motion control algorithms, and intelligent assistive wearable devices capable to effectively ensure a proper dynamic coupling between human and robot

Development of Digital Control Systems for Wearable Mechatronic Devices: Applications in Musculoskeletal Rehabilitation of the Upper Limb

The potential for wearable mechatronic systems to assist with musculoskeletal rehabilitation of the upper limb has grown with the technology. One limiting factor to realizing the benefits of these devices as motion therapy tools is within the development of digital control solutions. Despite many device prototypes and research efforts in the surrounding fields, there are a lack of requirements, details, assessments, and comparisons of control system characteristics, components, and architectures in the literature. Pairing this with the complexity of humans, the devices, and their interactions makes it a difficult task for control system developers to determine the best solution for their desired applications. The objective of this thesis is to develop, evaluate, and compare control system solutions that are capable of tracking motion through the control of wearable mechatronic devices. Due to the immaturity of these devices, the design, implementation, and testing processes for the control systems is not well established. In order to improve the efficiency and effectiveness of these processes, control system development and evaluation tools have been proposed. The Wearable Mechatronics-Enabled Control Software framework was developed to enable the implementation and comparison of different control software solutions presented in the literature. This framework reduces the amount of restructuring and modification required to complete these development tasks. An integration testing protocol was developed to isolate different aspects of the control systems during testing. A metric suite is proposed that expands on the existing literature and allows for the measurement of more control characteristics. Together, these tools were used ii ABSTRACT iii to developed, evaluate, and compare control system solutions. Using the developed control systems, a series of experiments were performed that involved tracking elbow motion using wearable mechatronic elbow devices. The accuracy and repeatability of the motion tracking performances, the adaptability of the control models, and the resource utilization of the digital systems were measured during these experiments. Statistical analysis was performed on these metrics to compare between experimental factors. The results of the tracking performances show some of the highest accuracies for elbow motion tracking with these devices. The statistical analysis revealed many factors that significantly impact the tracking performance, such as visual feedback, motion training, constrained motion, motion models, motion inputs, actuation components, and control outputs. Furthermore, the completion of the experiments resulted in three first-time studies, such as the comparison of muscle activation models and the quantification of control system task timing and data storage needs. The successes of these experiments highlight that accurate motion tracking, using biological signals of the user, is possible, but that many more efforts are needed to obtain control solutions that are robust to variations in the motion and characteristics of the user. To guide the future development of these control systems, a national survey was conducted of therapists regarding their patient data collection and analysis methods. From the results of this survey, a series of requirements for software systems, that allow therapists to interact with the control systems of these devices, were collected. Increasing the participation of therapists in the development processes of wearable assistive devices will help to produce better requirements for developers. This will allow the customization of control systems for specific therapies and patient characteristics, which will increase the benefit and adoption rate of these devices within musculoskeletal rehabilitation programs

Robot-Aided Systems for Improving the Assessment of Upper Limb Spasticity: A Systematic Review

This article belongs to the Special Issue Sensors Technology for Medical Robotics.Spasticity is a motor disorder that causes stiffness or tightness of the muscles and can interfere with normal movement, speech, and gait. Traditionally, the spasticity assessment is carried out by clinicians using standardized procedures for objective evaluation. However, these procedures are manually performed and, thereby, they could be influenced by the clinician’s subjectivity or expertise. The automation of such traditional methods for spasticity evaluation is an interesting and emerging field in neurorehabilitation. One of the most promising approaches is the use of robot-aided systems. In this paper, a systematic review of systems focused on the assessment of upper limb (UL) spasticity using robotic technology is presented. A systematic search and review of related articles in the literature were conducted. The chosen works were analyzed according to the morphology of devices, the data acquisition systems, the outcome generation method, and the focus of intervention (assessment and/or training). Finally, a series of guidelines and challenges that must be considered when designing and implementing fully-automated robot-aided systems for the assessment of UL spasticity are summarized

Shear-promoted drug encapsulation into red blood cells: a CFD model and μ-PIV analysis

The present work focuses on the main parameters that influence shear-promoted encapsulation of drugs into erythrocytes. A CFD model was built to investigate the fluid dynamics of a suspension of particles flowing in a commercial micro channel. Micro Particle Image Velocimetry (μ-PIV) allowed to take into account for the real properties of the red blood cell (RBC), thus having a deeper understanding of the process. Coupling these results with an analytical diffusion model, suitable working conditions were defined for different values of haematocrit

Modelling the Physical Human-Exoskeleton Interface

L'abstract è presente nell'allegato / the abstract is in the attachmen

Book of Abstracts 15th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and 3rd Conference on Imaging and Visualization

In this edition, the two events will run together as a single conference, highlighting the strong connection with the Taylor & Francis journals: Computer Methods in Biomechanics and Biomedical Engineering (John Middleton and Christopher Jacobs, Eds.) and Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization (JoãoManuel R.S. Tavares, Ed.). The conference has become a major international meeting on computational biomechanics, imaging andvisualization. In this edition, the main program includes 212 presentations. In addition, sixteen renowned researchers will give plenary keynotes, addressing current challenges in computational biomechanics and biomedical imaging. In Lisbon, for the first time, a session dedicated to award the winner of the Best Paper in CMBBE Journal will take place. We believe that CMBBE2018 will have a strong impact on the development of computational biomechanics and biomedical imaging and visualization, identifying emerging areas of research and promoting the collaboration and networking between participants. This impact is evidenced through the well-known research groups, commercial companies and scientific organizations, who continue to support and sponsor the CMBBE meeting series. In fact, the conference is enriched with five workshops on specific scientific topics and commercial software.info:eu-repo/semantics/draf

Biomechanics

Biomechanics is a vast discipline within the field of Biomedical Engineering. It explores the underlying mechanics of how biological and physiological systems move. It encompasses important clinical applications to address questions related to medicine using engineering mechanics principles. Biomechanics includes interdisciplinary concepts from engineers, physicians, therapists, biologists, physicists, and mathematicians. Through their collaborative efforts, biomechanics research is ever changing and expanding, explaining new mechanisms and principles for dynamic human systems. Biomechanics is used to describe how the human body moves, walks, and breathes, in addition to how it responds to injury and rehabilitation. Advanced biomechanical modeling methods, such as inverse dynamics, finite element analysis, and musculoskeletal modeling are used to simulate and investigate human situations in regard to movement and injury. Biomechanical technologies are progressing to answer contemporary medical questions. The future of biomechanics is dependent on interdisciplinary research efforts and the education of tomorrow’s scientists