18 research outputs found

    The use and reporting of airline passenger data for infectious disease modelling:a systematic review

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    Background A variety of airline passenger data sources are used for modelling the international spread of infectious diseases. Questions exist regarding the suitability and validity of these sources. Aim We conducted a systematic review to identify the sources of airline passenger data used for these purposes and to assess validation of the data and reproducibility of the methodology. Methods Articles matching our search criteria and describing a model of the international spread of human infectious disease, parameterised with airline passenger data, were identified. Information regarding type and source of airline passenger data used was collated and the studies’ reproducibility assessed. Results We identified 136 articles. The majority (n = 96) sourced data primarily used by the airline industry. Governmental data sources were used in 30 studies and data published by individual airports in four studies. Validation of passenger data was conducted in only seven studies. No study was found to be fully reproducible, although eight were partially reproducible. Limitations By limiting the articles to international spread, articles focussed on within-country transmission even if they used relevant data sources were excluded. Authors were not contacted to clarify their methods. Searches were limited to articles in PubMed, Web of Science and Scopus. Conclusion We recommend greater efforts to assess validity and biases of airline passenger data used for modelling studies, particularly when model outputs are to inform national and international public health policies. We also recommend improving reporting standards and more detailed studies on biases in commercial and open-access data to assess their reproducibility

    Epidemic spread and variation of peak times in connected regions due to travel-related infections-dynamics of an antigravity-type delay differential model

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    National boundaries have never prevented infectious diseases from reaching distant territories; however, the speed at which an infectious agent can spread around the world via the global airline transportation network has significantly increased during recent decades. We introduce an SEAIR-based, antigravity model to investigate the spread of an infectious disease in two regions which are connected by transportation. As a submodel, an age-structured system is constructed to incorporate the possibility of disease transmission during travel, where age is the time elapsed since the start of the travel. The model is equivalent to a large system of differential equations with dynamically defined delayed feedback. After describing fundamental but biologically relevant properties of the system, we detail the calculation of the basic reproduction number and obtain disease transmission dynamics results in terms of R0\mathcal{R}_0. We parametrize our model for influenza and use real demographic and air travel data for the numerical simulations. To understand the role of the different characteristics of the regions in the propagation of the disease, three distinct origin-destination pairs are considered. The model is also fitted to the first wave of the influenza A(H1N1) 2009 pandemic in Mexico and Canada. Our results highlight the importance of including travel time and disease dynamics during travel in the model: the invasion of disease-free regions is highly expedited by elevated transmission potential during transportation

    Aerospace medicine and biology: A continuing bibliography with indexes, supplement 183

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    This bibliography lists 273 reports, articles, and other documents introduced into the NASA scientific and technical information system in July 1978

    Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 127, April 1974

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    This special bibliography lists 279 reports, articles, and other documents introduced into the NASA scientific and technical information system in March 1974

    A multiscale modelling of the cardiovascular fluid dynamics for clinical and space applications

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    L'abstract è presente nell'allegato / the abstract is in the attachmen

    Aerospace medicine and biology - a continuing bibliography

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    Aerospace medicine and biology - bibliograph
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