The Entropy Principle and the Influence of Sociological Pressures on SETI

We begin with the premise that the law of entropy could prove to be fundamental for the evolution of intelligent life and the advent of technological civilization. Building on recent theoretical results, we combine a modern approach to evolutionary theory with Monte Carlo Realization Techniques. A numerical test for a proposed significance of the law of entropy within the evolution of intelligent species is performed and results are compared with a neutral test hypothesis. Some clarifying aspects on the emergence of intelligent species arise and are discussed in the framework of contemporary astrobiology.Comment: 11 pages, 5 figures, accepted for publication in the International Journal of Astrobiolog

A Survey on Soft Subspace Clustering

Subspace clustering (SC) is a promising clustering technology to identify clusters based on their associations with subspaces in high dimensional spaces. SC can be classified into hard subspace clustering (HSC) and soft subspace clustering (SSC). While HSC algorithms have been extensively studied and well accepted by the scientific community, SSC algorithms are relatively new but gaining more attention in recent years due to better adaptability. In the paper, a comprehensive survey on existing SSC algorithms and the recent development are presented. The SSC algorithms are classified systematically into three main categories, namely, conventional SSC (CSSC), independent SSC (ISSC) and extended SSC (XSSC). The characteristics of these algorithms are highlighted and the potential future development of SSC is also discussed.Comment: This paper has been published in Information Sciences Journal in 201

Fusion based Image Enhancement Approach for Brain Tumor Detection

Magnetic Resonance Imaging (MRI), is a crucial technology used in the processing of medical images that provides insights into the anatomy of soft organs in the human body and helps in detecting brain tumors and spinal tumors. Despite advances in technology, most images have intrinsic drawbacks such as reduced contrast and brightness, and noise. Several contrast enhancement techniques are used such as, HE, BBHE, DSIHE, CLAHE, RMSHE, and their fusion, have been deployed on different MRI images to handle these problems. Metrics such as, entropy, PIQE and BRISQUE are used in the assessment of the results. Through the different fusion combinations, most prominent results are obtained from CLAHE-RMSHE fusion with an entropy value of 6.2516 and BRISQUE value of 40.14

ProtNN: Fast and Accurate Nearest Neighbor Protein Function Prediction based on Graph Embedding in Structural and Topological Space

Studying the function of proteins is important for understanding the molecular mechanisms of life. The number of publicly available protein structures has increasingly become extremely large. Still, the determination of the function of a protein structure remains a difficult, costly, and time consuming task. The difficulties are often due to the essential role of spatial and topological structures in the determination of protein functions in living cells. In this paper, we propose ProtNN, a novel approach for protein function prediction. Given an unannotated protein structure and a set of annotated proteins, ProtNN finds the nearest neighbor annotated structures based on protein-graph pairwise similarities. Given a query protein, ProtNN finds the nearest neighbor reference proteins based on a graph representation model and a pairwise similarity between vector embedding of both query and reference protein-graphs in structural and topological spaces. ProtNN assigns to the query protein the function with the highest number of votes across the set of k nearest neighbor reference proteins, where k is a user-defined parameter. Experimental evaluation demonstrates that ProtNN is able to accurately classify several datasets in an extremely fast runtime compared to state-of-the-art approaches. We further show that ProtNN is able to scale up to a whole PDB dataset in a single-process mode with no parallelization, with a gain of thousands order of magnitude of runtime compared to state-of-the-art approaches