Genetic Deep Convolutional Autoencoder Applied for Generative Continuous Arterial Blood Pressure via Photoplethysmography

Hypertension affects huge number of people around the world. It also has a great contribution to cardiovascular and renal related diseases. This study investigates the ability deep convolutional autoencoder (DCAE) to generate the continuous arterial blood pressure (ABP) by only utilizing the photoplethysmography (PPG) to generate the continuous ABP. The total of 18 patients is utilized. LeNet-5 and U-Net based DCAEs, respectively for LDCAE and UDCAE, are compared to the MP60 IntelliVue Patient Monitor, as the golden standard. Moreover, in order to investigate the data generalization, leave-one-out cross-validation (CV) method is conducted. The results show that the UDCAE provides superior results in producing the SBP estimation. Meanwhile, LDCAE gives a slightly better for the DBP prediction. Finally, the genetic algorithm (GA) based optimization deep convolutional autoencoder (GDCAE) is further administered to optimize the ensemble of the CV models. The results reveal that the GDCAE is superior to either the LDCAE or UDCAE. For conclusion, this study reveals that the SBP and DBP can also be accurately achieved by only utilizing the single PPG signal

Computational Intelligence in Healthcare

The number of patient health data has been estimated to have reached 2314 exabytes by 2020. Traditional data analysis techniques are unsuitable to extract useful information from such a vast quantity of data. Thus, intelligent data analysis methods combining human expertise and computational models for accurate and in-depth data analysis are necessary. The technological revolution and medical advances made by combining vast quantities of available data, cloud computing services, and AI-based solutions can provide expert insight and analysis on a mass scale and at a relatively low cost. Computational intelligence (CI) methods, such as fuzzy models, artificial neural networks, evolutionary algorithms, and probabilistic methods, have recently emerged as promising tools for the development and application of intelligent systems in healthcare practice. CI-based systems can learn from data and evolve according to changes in the environments by taking into account the uncertainty characterizing health data, including omics data, clinical data, sensor, and imaging data. The use of CI in healthcare can improve the processing of such data to develop intelligent solutions for prevention, diagnosis, treatment, and follow-up, as well as for the analysis of administrative processes. The present Special Issue on computational intelligence for healthcare is intended to show the potential and the practical impacts of CI techniques in challenging healthcare applications

The Unbalanced Classification Problem: Detecting Breaches in Security

This research proposes several methods designed to improve solutions for security classification problems. The security classification problem involves unbalanced, high-dimensional, binary classification problems that are prevalent today. The imbalance within this data involves a significant majority of the negative class and a minority positive class. Any system that needs protection from malicious activity, intruders, theft, or other types of breaches in security must address this problem. These breaches in security are considered instances of the positive class. Given numerical data that represent observations or instances which require classification, state of the art machine learning algorithms can be applied. However, the unbalanced and high-dimensional structure of the data must be considered prior to applying these learning methods. High-dimensional data poses a “curse of dimensionality” which can be overcome through the analysis of subspaces. Exploration of intelligent subspace modeling and the fusion of subspace models is proposed. Detailed analysis of the one-class support vector machine, as well as its weaknesses and proposals to overcome these shortcomings are included. A fundamental method for evaluation of the binary classification model is the receiver operating characteristic (ROC) curve and the area under the curve (AUC). This work details the underlying statistics involved with ROC curves, contributing a comprehensive review of ROC curve construction and analysis techniques to include a novel graphic for illustrating the connection between ROC curves and classifier decision values. The major innovations of this work include synergistic classifier fusion through the analysis of ROC curves and rankings, insight into the statistical behavior of the Gaussian kernel, and novel methods for applying machine learning techniques to defend against computer intrusion detection. The primary empirical vehicle for this research is computer intrusion detection data, and both host-based intrusion detection systems (HIDS) and network-based intrusion detection systems (NIDS) are addressed. Empirical studies also include military tactical scenarios

Temporal Information in Data Science: An Integrated Framework and its Applications

Data science is a well-known buzzword, that is in fact composed of two distinct keywords, i.e., data and science. Data itself is of great importance: each analysis task begins from a set of examples. Based on such a consideration, the present work starts with the analysis of a real case scenario, by considering the development of a data warehouse-based decision support system for an Italian contact center company. Then, relying on the information collected in the developed system, a set of machine learning-based analysis tasks have been developed to answer specific business questions, such as employee work anomaly detection and automatic call classification. Although such initial applications rely on already available algorithms, as we shall see, some clever analysis workflows had also to be developed. Afterwards, continuously driven by real data and real world applications, we turned ourselves to the question of how to handle temporal information within classical decision tree models. Our research brought us the development of J48SS, a decision tree induction algorithm based on Quinlan's C4.5 learner, which is capable of dealing with temporal (e.g., sequential and time series) as well as atemporal (such as numerical and categorical) data during the same execution cycle. The decision tree has been applied into some real world analysis tasks, proving its worthiness. A key characteristic of J48SS is its interpretability, an aspect that we specifically addressed through the study of an evolutionary-based decision tree pruning technique. Next, since a lot of work concerning the management of temporal information has already been done in automated reasoning and formal verification fields, a natural direction in which to proceed was that of investigating how such solutions may be combined with machine learning, following two main tracks. First, we show, through the development of an enriched decision tree capable of encoding temporal information by means of interval temporal logic formulas, how a machine learning algorithm can successfully exploit temporal logic to perform data analysis. Then, we focus on the opposite direction, i.e., that of employing machine learning techniques to generate temporal logic formulas, considering a natural language processing scenario. Finally, as a conclusive development, the architecture of a system is proposed, in which formal methods and machine learning techniques are seamlessly combined to perform anomaly detection and predictive maintenance tasks. Such an integration represents an original, thrilling research direction that may open up new ways of dealing with complex, real-world problems.Data science is a well-known buzzword, that is in fact composed of two distinct keywords, i.e., data and science. Data itself is of great importance: each analysis task begins from a set of examples. Based on such a consideration, the present work starts with the analysis of a real case scenario, by considering the development of a data warehouse-based decision support system for an Italian contact center company. Then, relying on the information collected in the developed system, a set of machine learning-based analysis tasks have been developed to answer specific business questions, such as employee work anomaly detection and automatic call classification. Although such initial applications rely on already available algorithms, as we shall see, some clever analysis workflows had also to be developed. Afterwards, continuously driven by real data and real world applications, we turned ourselves to the question of how to handle temporal information within classical decision tree models. Our research brought us the development of J48SS, a decision tree induction algorithm based on Quinlan's C4.5 learner, which is capable of dealing with temporal (e.g., sequential and time series) as well as atemporal (such as numerical and categorical) data during the same execution cycle. The decision tree has been applied into some real world analysis tasks, proving its worthiness. A key characteristic of J48SS is its interpretability, an aspect that we specifically addressed through the study of an evolutionary-based decision tree pruning technique. Next, since a lot of work concerning the management of temporal information has already been done in automated reasoning and formal verification fields, a natural direction in which to proceed was that of investigating how such solutions may be combined with machine learning, following two main tracks. First, we show, through the development of an enriched decision tree capable of encoding temporal information by means of interval temporal logic formulas, how a machine learning algorithm can successfully exploit temporal logic to perform data analysis. Then, we focus on the opposite direction, i.e., that of employing machine learning techniques to generate temporal logic formulas, considering a natural language processing scenario. Finally, as a conclusive development, the architecture of a system is proposed, in which formal methods and machine learning techniques are seamlessly combined to perform anomaly detection and predictive maintenance tasks. Such an integration represents an original, thrilling research direction that may open up new ways of dealing with complex, real-world problems

NILM techniques for intelligent home energy management and ambient assisted living: a review

The ongoing deployment of smart meters and different commercial devices has made electricity disaggregation feasible in buildings and households, based on a single measure of the current and, sometimes, of the voltage. Energy disaggregation is intended to separate the total power consumption into specific appliance loads, which can be achieved by applying Non-Intrusive Load Monitoring (NILM) techniques with a minimum invasion of privacy. NILM techniques are becoming more and more widespread in recent years, as a consequence of the interest companies and consumers have in efficient energy consumption and management. This work presents a detailed review of NILM methods, focusing particularly on recent proposals and their applications, particularly in the areas of Home Energy Management Systems (HEMS) and Ambient Assisted Living (AAL), where the ability to determine the on/off status of certain devices can provide key information for making further decisions. As well as complementing previous reviews on the NILM field and providing a discussion of the applications of NILM in HEMS and AAL, this paper provides guidelines for future research in these topics.Agência financiadora: Programa Operacional Portugal 2020 and Programa Operacional Regional do Algarve 01/SAICT/2018/39578 Fundação para a Ciência e Tecnologia through IDMEC, under LAETA: SFRH/BSAB/142998/2018 SFRH/BSAB/142997/2018 UID/EMS/50022/2019 Junta de Comunidades de Castilla-La-Mancha, Spain: SBPLY/17/180501/000392 Spanish Ministry of Economy, Industry and Competitiveness (SOC-PLC project): TEC2015-64835-C3-2-R MINECO/FEDERinfo:eu-repo/semantics/publishedVersio

On the development of intelligent medical systems for pre-operative anaesthesia assessment

This thesis describes the research and development of a decision support tool for determining a medical patient's suitability for surgical anaesthesia. At present, there is a change in the way that patients are clinically assessedp rior to surgery. The pre-operative assessment, usually conducted by a qualified anaesthetist, is being more frequently performed by nursing grade staff. The pre-operative assessmenet xists to minimise the risk of surgical complications for the patient. Nursing grade staff are often not as experienced as qualified anaesthetists, and thus are not as well suited to the role of performing the pre-operative assessment. This research project used data collected during pre-operative assessments to develop a decision support tool that would assist the nurse (or anaesthetist) in determining whether a patient is suitable for surgical anaesthesia. The three main objectives are: firstly, to research and develop an automated intelligent systems technique for classifying heart and lung sounds and hence identifying cardio-respiratory pathology. Secondly, to research and develop an automated intelligent systems technique for assessing the patient's blood oxygen level and pulse waveform. Finally, to develop a decision support tool that would combine the assessmentsa bove in forming a decision as to whether the patient is suitable for surgical anaesthesia. Clinical data were collected from hospital outpatient departments and recorded alongside the diagnoses made by a qualified anaesthetist. Heart and lung sounds were collected using an electronic stethoscope. Using this data two ensembles of artificial neural networks were trained to classify the different heart and lung sounds into different pathology groups. Classification accuracies up to 99.77% for the heart sounds, and 100% for the lung sounds has been obtained. Oxygen saturation and pulse waveform measurements were recorded using a pulse oximeter. Using this data an artificial neural network was trained to discriminate between normal and abnormal pulse waveforms. A discrimination accuracy of 98% has been obtained from the system. A fuzzy inference system was generated to classify the patient's blood oxygen level as being either an inhibiting or non-inhibiting factor in their suitability for surgical anaesthesia. When tested the system successfully classified 100% of the test dataset. A decision support tool, applying the genetic programming evolutionary technique to a fuzzy classification system was created. The decision support tool combined the results from the heart sound, lung sound and pulse oximetry classifiers in determining whether a patient was suitable for surgical anaesthesia. The evolved fuzzy system attained a classification accuracy of 91.79%. The principal conclusion from this thesis is that intelligent systems, such as artificial neural networks, genetic programming, and fuzzy inference systems, can be successfully applied to the creation of medical decision support tools.EThOS - Electronic Theses Online ServiceMedicdirect.co.uk Ltd.GBUnited Kingdo

Industrial Applications: New Solutions for the New Era

This book reprints articles from the Special Issue "Industrial Applications: New Solutions for the New Age" published online in the open-access journal Machines (ISSN 2075-1702). This book consists of twelve published articles. This special edition belongs to the "Mechatronic and Intelligent Machines" section

Tracking the Temporal-Evolution of Supernova Bubbles in Numerical Simulations

The study of low-dimensional, noisy manifolds embedded in a higher dimensional space has been extremely useful in many applications, from the chemical analysis of multi-phase flows to simulations of galactic mergers. Building a probabilistic model of the manifolds has helped in describing their essential properties and how they vary in space. However, when the manifold is evolving through time, a joint spatio-temporal modelling is needed, in order to fully comprehend its nature. We propose a first-order Markovian process that propagates the spatial probabilistic model of a manifold at fixed time, to its adjacent temporal stages. The proposed methodology is demonstrated using a particle simulation of an interacting dwarf galaxy to describe the evolution of a cavity generated by a Supernov