Index modulation for next generation wireless communications.

Doctoral Degree. University of KwaZulu-Natal, Durban.A multicarrier index modulation technique in the form of quadrature spatial modulation (QSM) orthogonal frequency division multiplexing (QSM-OFDM) is proposed, in which transmit antenna indices are employed to transmit additional bits. Monte Carlo simulation results demonstrates a 5 dB gain in signal-to-noise ratio (SNR) over other OFDM schemes. Furthermore, an analysis of the receiver computational complexity is presented. A low-complexity near-ML detector for space-time block coded (STBC) spatial modulation (STBC-SM) with cyclic structure (STBC-CSM), which demonstrate near-ML error performance and yields significant reduction in computational complexity is proposed. In addition, the union-bound theoretical framework to quantify the average bit-error probability (ABEP) of STBC-CSM is formulated and validates the Monte Carlo simulation results. The application of media-based modulation (MBM), to STBC-SM and STBC-CSM employing radio frequency (RF) mirrors, in the form of MBSTBC-SM and MBSTBC-CSM is proposed to improve the error performance. Numerical results of the proposed schemes demonstrate significant improvement in error performance when compared with STBC-CSM and STBC-SM. In addition, the analytical framework of the union-bound on the ABEP of MBSTBC-SM and MBSTBC-CSM for the ML detector is formulated and agrees well with Monte Carlo simulations. Furthermore, a low-complexity near-ML detector for MBSTBC-SM and MBSTBC-CSM is proposed, and achieves a near-ML error performance. Monte Carlo simulation results demonstrate a trade-off between the error performance and the resolution of the detector that is employed. Finally, the application of MBM, an index modulated system to spatial modulation, in the form of spatial MBM (SMBM) is investigated. SMBM employs RF mirrors located around the transmit antenna units to create distinct channel paths to the receiver. This thesis presents an easy to evaluate theoretical bound for the error performance of SMBM, which is validated by Monte Carlo simulation results. Lastly, two low-complexity suboptimal mirror activation pattern (MAP) optimization techniques are proposed, which improve the error performance of SMBM significantly

Modulation options for OFDM-based waveforms: classification, comparison, and future directions

This paper provides a comparative study on the performance of different modulation options for orthogonal frequency division multiplexing (OFDM) in terms of their spectral efficiency, reliability, peak-to-average power ratio, power efficiency, out-of-band emission, and computational complexity. The modulation candidates are classified into two main categories based on the signal plane dimension they exploit. These categories are: 1) 2-D signal plane category including conventional OFDM with classical fixed or adaptive QAM modulation and OFDM with differential modulation, where information is conveyed in changes between two successive symbols in the same subcarrier or between two consecutive subcarriers in the same OFDM symbol and 2) 3-D signal plane category encompassing: a) index-based OFDM modulation schemes which include: i) spatial modulation OFDM, where information is sent by the indices of antennas along with conventional modulated symbols and ii) OFDM with index modulation, where the subcarriers’ indices are used to send additional information; b) number-based OFDM modulation schemes which include OFDM with subcarrier number modulation, in which number of subcarriers is exploited to convey additional information; and c) shape-based OFDM modulation schemes which include OFDM with pulse superposition modulation, where the shape of pulses is introduced as a third new dimension to convey additional information. Based on the provided comparative study, the relationship and interaction between these different modulation options and the requirements of future 5G networks are discussed and explained. This paper is then concluded with some recommendations and future research directions.This work was supported in part by the Scientific and Technological Research Council of Turkey (TUBITAK), under Grant 215E316

Investigation Of The Spatiotemporal Dynamics Of Camp And Pka Signaling And The Role Of Hcn4 Subunits In Anxiety-Related Behavior And Memory

In the hippocampus, long-term memory and synaptic plasticity occur through a series of coordinated intracellular signaling cascades that strengthen and stabilize subsets of synaptic connections while leaving thousands of others unaltered. Therefore, understanding how molecular signals are accurately transmitted is critical to understanding how hippocampal neurons store information. Molecules like cAMP and protein kinase A are critical components of memory and plasticity, but it is unclear how these diffusible signals are dynamically regulated to achieve the spatial and temporal specificity that underlies pathway-specific plasticity. Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels are ion channels that are modulated by cAMP and are known to regulate the spatial and temporal dynamics of excitatory postsynaptic potentials. HCN1 and HCN2 subunits have been implicated in memory, plasticity and anxiety-related behaviors, but the role for HCN4 subunits remains untested. In Chapter 1, I review the role of cAMP signaling in hippocampal synaptic plasticity and memory consolidation with emphasis on the molecular mechanisms regulating cAMP, PKA and HCN channels. In Chapter 2, I combine live two-photon imaging of genetically-encoded fluorescent FRET sensors and computational modeling to investigate the molecular mechanisms regulating the spatiotemporal dynamics of cAMP and PKA activity in hippocampal neurons during stimulation of β-adrenergic receptors. Results suggest that the ratio between adenylyl cyclase and phosphodiesterase-4 scales with neuronal compartment size to maintain basal cAMP levels and produce rapid-onset, high-amplitude cAMP transients in small compartments. Conversely, imaging experiments show that PKA activity is greater in large neuronal compartments and modeling suggests that compartmental differences in PKA activity depend on the concentration of protein phosphatase and not on the concentration of PKA substrates or PKA holoenzyme. In Chapter 3, I use recombinant adeno-associated viruses and shRNA-mediated silencing of HCN4 subunits to examine their role in anxiety, memory, and contextual fear extinction. Results from a battery of behavioral assays suggest that reduction of HCN4 subunits increases anxiety-related behavior, but does not affect object-location memory or contextual fear conditioning. Together, my thesis work provides novel insight into the molecular mechanism regulating the spatiotemporal dynamics of cAMP/PKA signaling and provides suggests a role for HCN4 subunits in anxiety-related behavior

Long-Term Plasticity Is Proportional to Theta-Activity

Background: Theta rhythm in the hippocampal formation is a main feature of exploratory behaviour and is believed to enable the encoding of new spatial information and the modification of synaptic weights. Cyclic changes of dentate gyrus excitability during theta rhythm are related to its function, but whether theta epochs per se are able to alter network properties of dentate gyrus for long time-periods is still poorly understood. Methodology/Principal Findings: We used low-frequency stimulation protocols that amplify the power of endogenous theta oscillations, in order to estimate the plasticity effect of endogenous theta oscillations on a population level. We found that stimulation-induced augmentation of the theta rhythm is linked to a subsequent increase of neuronal excitability and decrease of the synaptic response. This EPSP-to-Spike uncoupling is related to an increased postsynaptic spiking on the positive phases of theta frequency oscillations. Parallel increase of the field EPSP slope and the population spike occurs only after concurrent pre- and postsynaptic activation. Furthermore, we observed that long-term potentiation (.24 h) occurs in the dentate gyrus of freely behaving adult rats after phasic activity of entorhinal afferents in the theta-frequency range. This plasticity is proportional to the field bursting activity of granule cells during the stimulation, and may comprise a key step in spatial information transfer. Long-term potentiation of the synaptic component occurs only when the afferent stimulus precedes the evoked population burst, and is input-specific

Performance Assessment of Dual-Polarized 5G Waveforms and Beyond in Directly Modulated DFB-Laser using Volterra Equalizer

International audienceWe investigate the performance of 25-Gbps dual-polarized orthogonal frequency division multiplexing (OFDM)-based modulation in a directly modulated distributed feedback (DFB)-laser over 25 km of single-mode fiber. A Volterra equalizer is used to compensate for the nonlinear effects of the optical fiber. The results show that FBMC-OQAM modulation outperforms OFDM, universal filtered multicarrier (UFMC), and generalized frequency division multiplexing (GFDM) waveforms. Indeed, a target bit error rate of similar to 3.8 x 10(-3) [forward error correction (FEC) limit] for FBMC, UFMC, OFDM, and GFDM can be achieved at -30.5, -26, -16, and -14.9 dBm, respectively. The effect of the DFB laser is also investigated for UFMC, OFDM, and GFDM, and they undergo a Q penalty of 2.44, 2.77, and 4.14 dB, respectively, at their FEC limit points. For FBMC-OQAM, the signal is perfectly recovered when excluding the DFB laser at -30.5 dBm. (C) 2020 Society of Photo-Optical Instrumentation Engineers (SPIE