30 research outputs found

    A cloud-based bioinformatic analytic infrastructure and Data Management Core for the Expanded Program on Immunization Consortium.

    Get PDF
    The Expanded Program for Immunization Consortium - Human Immunology Project Consortium study aims to employ systems biology to identify and characterize vaccine-induced biomarkers that predict immunogenicity in newborns. Key to this effort is the establishment of the Data Management Core (DMC) to provide reliable data and bioinformatic infrastructure for centralized curation, storage, and analysis of multiple de-identified "omic" datasets. The DMC established a cloud-based architecture using Amazon Web Services to track, store, and share data according to National Institutes of Health standards. The DMC tracks biological samples during collection, shipping, and processing while capturing sample metadata and associated clinical data. Multi-omic datasets are stored in access-controlled Amazon Simple Storage Service (S3) for data security and file version control. All data undergo quality control processes at the generating site followed by DMC validation for quality assurance. The DMC maintains a controlled computing environment for data analysis and integration. Upon publication, the DMC deposits finalized datasets to public repositories. The DMC architecture provides resources and scientific expertise to accelerate translational discovery. Robust operations allow rapid sharing of results across the project team. Maintenance of data quality standards and public data deposition will further benefit the scientific community

    Método para el desarrollo de software seguro basado en la ingeniería de software y ciberseguridad

    Get PDF
    The increase in computer attacks is in increasing demand, nowadays cybercrime to which our data is exposed is more frequent. On the other hand, the management of software and tools used in computer science is what represents today a fundamental pillar in what teaching and scientific research refers, however, the concept goes far beyond that, of the hand of computer security that involves many more factors than are believed, not only physical but logical, referring to all the applications that run on each of the computers and that are part of the software. This paper presents a secure software model based on the software development life cycle and aims to create professionals capable of developing secure software products and at the same time raise awareness of the various problems that may arise from not establishing security measures in Systems development A final analysis of the importance of creating professionals with knowledge of the use and application of computer security is carried out.El incremento de los ataques informáticos va en creciente demanda, hoy en día es más frecuente los ciberdelitos a los que nuestros datos están expuestos. Por otro lado, el manejo que se tiene del software y las herramientas utilizadas en informática es lo que representa hoy en día un pilar fundamental en lo que enseñanza e investigación científica se refiere, sin embargo, el concepto va mucho más allá de ello, de la mano de la seguridad informática que involucra muchos más factores de los que se creen, no solo físicos sino lógicos, refiriéndose a todas las aplicaciones que ejecutan en cada uno de los equipos y que forman parte del software. Este trabajo presenta un modelo de software seguro basado en el ciclo de vida de desarrollo de software y pretende crear profesionales capaces de desarrollar productos seguros de software y al mismo tiempo crear conciencia ante los diversos problemas que se pueden originar al no establecer medidas de seguridad en el desarrollo de sistemas. Se realiza un análisis final de la importancia que tiene crear profesionales con conocimiento del uso y aplicación de la seguridad informática

    Impacto de los canales de comercialización online en tiempos del COVID-19

    Get PDF
    Peruvian companies, specifically in Metropolitan Lima, due to the situation of COVID-19, are immersed in the challenge of implementing options to generate sales. Are online marketing channels a good alternative to reactivate trade in goods and services in times of COVID-19? The general objective of this research was to identify how online marketing channels impact sales in times of COVID-19 in Metropolitan Lima 2020. The focus of the research was quantitative, basic type, explanatory level, non-experimental design and cross-sectional. The population under study consisted of 267 inhabitants of the city of Metropolitan Lima, of both sexes, from 18 to 55 years old. The technique used was the survey, the instrument was the questionnaire, with a global statistic of Cronbach's alpha reliability of 0,912. The inferential results of Pearson's Chi-square test, show that online marketing channels (with a highly significant level 0.00 < 0.05) do have an impact on the increase of sales in times of COVID-19. It is also identified that, if there is impact between online marketing channels and purchase intention, so with purchase risk. Finally, it is concluded that online marketing channels are highly linked to the level of expenditure and purchase satisfaction, i.e., the use of online marketing channels has a great impact on the level of expenditure and purchase satisfaction.  Las empresas peruanas, específicamente en Lima Metropolitana, debido a la coyuntura del COVID-19, se encuentran inmersas en el reto de implementar opciones para generar ventas ¿Son los canales de comercialización Online, una buena alternativa de reactivación del comercio de bienes y servicios en tiempos de COVID-19? El presente trabajo de investigación tuvo como objetivo general identificar cómo los canales de comercialización online impactan en las ventas en tiempos de COVID-19 en Lima Metropolitana 2020. El enfoque de la investigación fue cuantitativo, tipo básica, de nivel explicativo, diseño no experimental y de corte transversal. La población objeto de estudio estuvo conformada por 267 habitantes de la ciudad de Lima Metropolitana, de ambos sexos, de 18 a 55 años. La técnica utilizada fue la encuesta, el instrumento fue el cuestionario, con un estadístico global de fiabilidad alfa de Cronbach de 0,912.  Los resultados inferenciales de la prueba Chi cuadrado de Pearson, demuestran que los canales de comercialización online (con un nivel altamente significativo 0,00 < 0,05) si tiene impacto en el incremento de las ventas en tiempos de COVID-19. Se identifica también que, si existe impacto entre los canales de comercialización online y la intención de compra, así también con riesgo de compra. Se concluye finalmente que, los canales de comercialización online están altamente vinculados con el nivel de gasto y con la satisfacción de compra, es decir que el uso de los canales de comercialización online si tiene un gran impacto en el nivel del gasto y la satisfacción de compra.&nbsp

    Usability analysis of contending electronic health record systems

    Get PDF
    In this paper, we report measured usability of two leading EHR systems during procurement. A total of 18 users participated in paired-usability testing of three scenarios: ordering and managing medications by an outpatient physician, medicine administration by an inpatient nurse and scheduling of appointments by nursing staff. Data for audio, screen capture, satisfaction rating, task success and errors made was collected during testing. We found a clear difference between the systems for percentage of successfully completed tasks, two different satisfaction measures and perceived learnability when looking at the results over all scenarios. We conclude that usability should be evaluated during procurement and the difference in usability between systems could be revealed even with fewer measures than were used in our study. © 2019 American Psychological Association Inc. All rights reserved.Peer reviewe

    ERP implementation methodologies and frameworks: a literature review

    Get PDF
    Enterprise Resource Planning (ERP) implementation is a complex and vibrant process, one that involves a combination of technological and organizational interactions. Often an ERP implementation project is the single largest IT project that an organization has ever launched and requires a mutual fit of system and organization. Also the concept of an ERP implementation supporting business processes across many different departments is not a generic, rigid and uniform concept and depends on variety of factors. As a result, the issues addressing the ERP implementation process have been one of the major concerns in industry. Therefore ERP implementation receives attention from practitioners and scholars and both, business as well as academic literature is abundant and not always very conclusive or coherent. However, research on ERP systems so far has been mainly focused on diffusion, use and impact issues. Less attention has been given to the methods used during the configuration and the implementation of ERP systems, even though they are commonly used in practice, they still remain largely unexplored and undocumented in Information Systems research. So, the academic relevance of this research is the contribution to the existing body of scientific knowledge. An annotated brief literature review is done in order to evaluate the current state of the existing academic literature. The purpose is to present a systematic overview of relevant ERP implementation methodologies and frameworks as a desire for achieving a better taxonomy of ERP implementation methodologies. This paper is useful to researchers who are interested in ERP implementation methodologies and frameworks. Results will serve as an input for a classification of the existing ERP implementation methodologies and frameworks. Also, this paper aims also at the professional ERP community involved in the process of ERP implementation by promoting a better understanding of ERP implementation methodologies and frameworks, its variety and history

    Eleven quick tips for architecting biomedical informatics workflows with cloud computing.

    No full text
    Cloud computing has revolutionized the development and operations of hardware and software across diverse technological arenas, yet academic biomedical research has lagged behind despite the numerous and weighty advantages that cloud computing offers. Biomedical researchers who embrace cloud computing can reap rewards in cost reduction, decreased development and maintenance workload, increased reproducibility, ease of sharing data and software, enhanced security, horizontal and vertical scalability, high availability, a thriving technology partner ecosystem, and much more. Despite these advantages that cloud-based workflows offer, the majority of scientific software developed in academia does not utilize cloud computing and must be migrated to the cloud by the user. In this article, we present 11 quick tips for architecting biomedical informatics workflows on compute clouds, distilling knowledge gained from experience developing, operating, maintaining, and distributing software and virtualized appliances on the world's largest cloud. Researchers who follow these tips stand to benefit immediately by migrating their workflows to cloud computing and embracing the paradigm of abstraction

    Eleven quick tips for architecting biomedical informatics workflows with cloud computing

    No full text
    <div><p>Cloud computing has revolutionized the development and operations of hardware and software across diverse technological arenas, yet academic biomedical research has lagged behind despite the numerous and weighty advantages that cloud computing offers. Biomedical researchers who embrace cloud computing can reap rewards in cost reduction, decreased development and maintenance workload, increased reproducibility, ease of sharing data and software, enhanced security, horizontal and vertical scalability, high availability, a thriving technology partner ecosystem, and much more. Despite these advantages that cloud-based workflows offer, the majority of scientific software developed in academia does not utilize cloud computing and must be migrated to the cloud by the user. In this article, we present 11 quick tips for architecting biomedical informatics workflows on compute clouds, distilling knowledge gained from experience developing, operating, maintaining, and distributing software and virtualized appliances on the world’s largest cloud. Researchers who follow these tips stand to benefit immediately by migrating their workflows to cloud computing and embracing the paradigm of abstraction.</p></div

    Business process modelling in ERP implementation literature review

    Get PDF
    Business processes are the backbone of any Enterprise Resource Planning (ERP) implementation. Business process modelling (BPM) has become essential for modern, process driven enterprises due to the vibrant business environments. As a consequence enterprises are dealing with a substantial rate of organizational and business processes change. Business process modelling enables a common understanding and analysis of the business processes, which is the first step in every ERP implementation methodology (blueprint phase). In order to represent enterprise processes models in an accurate manner, it is paramount to choose a right business process modeling technique and tool. The problem of many ERP projects rated as unsuccessful is directly connected to a lack of use of business process models and notations during the blueprint phase. Also, blueprint implementation phase is crucial in order to fit planned processes in an organization with processes implemented in the solution. However, business analysts and ERP implementation professionals have substantial difficulties to navigate through a large number of theoretical models and representational notations that have been proposed for business process modeling (BPM). As the availability of different business process modeling references is huge, it is time consuming to make review and classification of all modeling techniques. Therefor, in reality majority of ERP implementations blueprint documents have no business process modeling included in generating blueprint documents. Choosing the right model comprise the purpose of the analysis and acquaintance of the available process modelling techniques and tools. The number of references on business modelling is quit large, so it is very hard to make a decision which modeling notation or technique to use. The main purpose of this paper is to make a review of business process modelling literature and describe the key process modelling techniques. The focus will be on all business process modeling that could be used in ERP implementations, specifically during the blueprint phase of the implementation process. Detailed review of BPM (Business process modeling) theoretical models and representational notations, should assist decision makers and ERP integrators in comparatively evaluating and selecting suitable modeling approaches

    A conceptual framework for capability sourcing modeling

    Get PDF
    Companies need to acquire the right capabilities from the right source, and the right shore, at the right cost to improve their competitive position. Capability sourcing is an organizing process to gain access to best-in-class capabilities for all activities in a firm's value chain to ensure long-term competitive advantage. Capability sourcing modeling is a technique that helps investigating sourcing alternative solutions to facilitate strategic sourcing decision making. Our position is applying conceptual models as intermediate artifacts which are schematic descriptions of sourcing alternatives based on organization's capabilities. The contribution of this paper is introducing a conceptual framework in the form of five views (to organize all perspectives) and a conceptualisation (to formulate a language) for capability sourcing modelling

    The creation of business architecture heat maps to support strategy-aligned organizational decisions

    Get PDF
    The realization of strategic alignment within the business architecture has become increasingly important for companies. Indeed, it facilitates business-IT alignment as a well-designed business architecture helps both to identify the appropriate requirements for IT systems and to discover new business opportunities that can be realized by IT. However, there is a lack of alignment techniques that support organizational (re) design decisions during the operation phase as the actual performance of business architecture elements is neglected. Capability heat maps provide a useful starting point in this respect as they focus on the creation of a hierarchy of prioritized capabilities, which are characterized by a performance measure. In this paper, these techniques will be extended to support strategy-aligned decisions within the business architecture. The identification of the relevant business architecture elements is based on state-of-the-art enterprise modelling languages, which enable the development of enterprise models on distinct layers of the business architecture. Strategic alignment between these elements will be realized by using prioritization according to the Analytic Hierarchy Process (AHP), while performance measurement will enable the creation of a proper decision support system. Afterwards, the proposed heat map will be applied on a case example to illustrate its potential use. This results in the completion of a first build-and-evaluate loop within the Design Science methodology
    corecore