Optimal Resource Allocation Using Deep Learning-Based Adaptive Compression For Mhealth Applications

In the last few years the number of patients with chronic diseases that require constant monitoring increases rapidly; which motivates the researchers to develop scalable remote health applications. Nevertheless, transmitting big real-time data through a dynamic network limited by the bandwidth, end-to-end delay and transmission energy; will be an obstacle against having an efficient transmission of the data. The problem can be resolved by applying data reduction techniques on the vital signs at the transmitter side and reconstructing the data at the receiver side (i.e. the m-Health center). However, a new problem will be introduced which is the ability to receive the vital signs at the server side with an acceptable distortion rate (i.e. deformation of vital signs because of inefficient data reduction). In this thesis, we integrate efficient data reduction with wireless networking to deliver an adaptive compression with an acceptable distortion, while reacting to the wireless network dynamics such as channel fading and user mobility. A Deep Learning (DL) approach was used to implement an adaptive compression technique to compress and reconstruct the vital signs in general and specifically the Electroencephalogram Signal (EEG) with the minimum distortion. Then, a resource allocation framework was introduced to minimize the transmission energy along with the distortion of the reconstructed signa

Real-time neural signal processing and low-power hardware co-design for wireless implantable brain machine interfaces

Intracortical Brain-Machine Interfaces (iBMIs) have advanced significantly over the past two decades, demonstrating their utility in various aspects, including neuroprosthetic control and communication. To increase the information transfer rate and improve the devices’ robustness and longevity, iBMI technology aims to increase channel counts to access more neural data while reducing invasiveness through miniaturisation and avoiding percutaneous connectors (wired implants). However, as the number of channels increases, the raw data bandwidth required for wireless transmission also increases becoming prohibitive, requiring efficient on-implant processing to reduce the amount of data through data compression or feature extraction. The fundamental aim of this research is to develop methods for high-performance neural spike processing co-designed within low-power hardware that is scaleable for real-time wireless BMI applications. The specific original contributions include the following: Firstly, a new method has been developed for hardware-efficient spike detection, which achieves state-of-the-art spike detection performance and significantly reduces the hardware complexity. Secondly, a novel thresholding mechanism for spike detection has been introduced. By incorporating firing rate information as a key determinant in establishing the spike detection threshold, we have improved the adaptiveness of spike detection. This eventually allows the spike detection to overcome the signal degradation that arises due to scar tissue growth around the recording site, thereby ensuring enduringly stable spike detection results. The long-term decoding performance, as a consequence, has also been improved notably. Thirdly, the relationship between spike detection performance and neural decoding accuracy has been investigated to be nonlinear, offering new opportunities for further reducing transmission bandwidth by at least 30% with minor decoding performance degradation. In summary, this thesis presents a journey toward designing ultra-hardware-efficient spike detection algorithms and applying them to reduce the data bandwidth and improve neural decoding performance. The software-hardware co-design approach is essential for the next generation of wireless brain-machine interfaces with increased channel counts and a highly constrained hardware budget. The fundamental aim of this research is to develop methods for high-performance neural spike processing co-designed within low-power hardware that is scaleable for real-time wireless BMI applications. The specific original contributions include the following: Firstly, a new method has been developed for hardware-efficient spike detection, which achieves state-of-the-art spike detection performance and significantly reduces the hardware complexity. Secondly, a novel thresholding mechanism for spike detection has been introduced. By incorporating firing rate information as a key determinant in establishing the spike detection threshold, we have improved the adaptiveness of spike detection. This eventually allows the spike detection to overcome the signal degradation that arises due to scar tissue growth around the recording site, thereby ensuring enduringly stable spike detection results. The long-term decoding performance, as a consequence, has also been improved notably. Thirdly, the relationship between spike detection performance and neural decoding accuracy has been investigated to be nonlinear, offering new opportunities for further reducing transmission bandwidth by at least 30\% with only minor decoding performance degradation. In summary, this thesis presents a journey toward designing ultra-hardware-efficient spike detection algorithms and applying them to reduce the data bandwidth and improve neural decoding performance. The software-hardware co-design approach is essential for the next generation of wireless brain-machine interfaces with increased channel counts and a highly constrained hardware budget.Open Acces

Hardware-efficient data compression in wireless intracortical brain-machine interfaces

Brain-Machine Interfaces (BMI) have emerged as a promising technology for restoring lost motor function in patients with neurological disorders and/or motor impairments, e.g. paraplegia, amputation, stroke, spinal cord injury, amyotrophic lateral sclerosis, etc. The past 2 decades have seen significant advances in BMI performance. This has largely been driven by the invention and uptake of intracortical microelectrode arrays that can isolate the activity of individual neurons. However, the current paradigm involves the use of percutaneous connections, i.e. wires. These wires carry the information from the intracortical array implanted in the brain to outside of the body, where the information is used for neural decoding. These wires carry significant long-term risks ranging from infection, to mechanical injury, to impaired mobility and quality of life for the individual. Therefore, there is a desire to make intracortical BMIs (iBMI) wireless, where the data is communicated out wirelessly, either with the use of electromagnetic or acoustic waves. Unfortunately, this consumes a significant amount of power, which is dissipated from the implant in the form of heat. Heating tissue can cause irreparable damage, and so there are strict limits on heat flux from implants to cortical tissue. Given the ever-increasing number of channels per implant, the required communication power is now exceeding the acceptable cortical heat transfer limits. This cortical heating issue is hampering widespread clinical use. As such, effective data compression would bring Wireless iBMIs (WI-BMI) into alignment with heat transfer limits, enabling large channel counts and small implant sizes without risking tissue damage via heating. This thesis addresses the aforementioned communication power problem from a signal processing and data compression perspective, and is composed of two parts. In the first part, we investigate hardware-efficient ways to compress the Multi-Unit Activity (MUA) signal, which is the most common signal in modern iBMIs. In the second and final part, we look at efficient ways to extract and compress the high-bandwidth Entire Spiking Activity signal, which, while underexplored as a signal, has been the subject of significant interest given its ability to outperform the MUA signal in neural decoding. Overall, this thesis introduces hardware-efficient methods of extracting high-performing neural features, and compressing them by an order of magnitude or more beyond the state-of-the-art in ultra-low power ways. This enables many more recording channels to be fit onto intracortical implants, while remaining within cortical heat transfer safety and channel capacity limits.Open Acces

Recent Advances in Signal Processing

The signal processing task is a very critical issue in the majority of new technological inventions and challenges in a variety of applications in both science and engineering fields. Classical signal processing techniques have largely worked with mathematical models that are linear, local, stationary, and Gaussian. They have always favored closed-form tractability over real-world accuracy. These constraints were imposed by the lack of powerful computing tools. During the last few decades, signal processing theories, developments, and applications have matured rapidly and now include tools from many areas of mathematics, computer science, physics, and engineering. This book is targeted primarily toward both students and researchers who want to be exposed to a wide variety of signal processing techniques and algorithms. It includes 27 chapters that can be categorized into five different areas depending on the application at hand. These five categories are ordered to address image processing, speech processing, communication systems, time-series analysis, and educational packages respectively. The book has the advantage of providing a collection of applications that are completely independent and self-contained; thus, the interested reader can choose any chapter and skip to another without losing continuity

Design of a secure architecture for the exchange of biomedical information in m-Health scenarios

El paradigma de m-Salud (salud móvil) aboga por la integración masiva de las más avanzadas tecnologías de comunicación, red móvil y sensores en aplicaciones y sistemas de salud, para fomentar el despliegue de un nuevo modelo de atención clínica centrada en el usuario/paciente. Este modelo tiene por objetivos el empoderamiento de los usuarios en la gestión de su propia salud (p.ej. aumentando sus conocimientos, promocionando estilos de vida saludable y previniendo enfermedades), la prestación de una mejor tele-asistencia sanitaria en el hogar para ancianos y pacientes crónicos y una notable disminución del gasto de los Sistemas de Salud gracias a la reducción del número y la duración de las hospitalizaciones. No obstante, estas ventajas, atribuidas a las aplicaciones de m-Salud, suelen venir acompañadas del requisito de un alto grado de disponibilidad de la información biomédica de sus usuarios para garantizar una alta calidad de servicio, p.ej. fusionar varias señales de un usuario para obtener un diagnóstico más preciso. La consecuencia negativa de cumplir esta demanda es el aumento directo de las superficies potencialmente vulnerables a ataques, lo que sitúa a la seguridad (y a la privacidad) del modelo de m-Salud como factor crítico para su éxito. Como requisito no funcional de las aplicaciones de m-Salud, la seguridad ha recibido menos atención que otros requisitos técnicos que eran más urgentes en etapas de desarrollo previas, tales como la robustez, la eficiencia, la interoperabilidad o la usabilidad. Otro factor importante que ha contribuido a retrasar la implementación de políticas de seguridad sólidas es que garantizar un determinado nivel de seguridad implica unos costes que pueden ser muy relevantes en varias dimensiones, en especial en la económica (p.ej. sobrecostes por la inclusión de hardware extra para la autenticación de usuarios), en el rendimiento (p.ej. reducción de la eficiencia y de la interoperabilidad debido a la integración de elementos de seguridad) y en la usabilidad (p.ej. configuración más complicada de dispositivos y aplicaciones de salud debido a las nuevas opciones de seguridad). Por tanto, las soluciones de seguridad que persigan satisfacer a todos los actores del contexto de m-Salud (usuarios, pacientes, personal médico, personal técnico, legisladores, fabricantes de dispositivos y equipos, etc.) deben ser robustas y al mismo tiempo minimizar sus costes asociados. Esta Tesis detalla una propuesta de seguridad, compuesta por cuatro grandes bloques interconectados, para dotar de seguridad a las arquitecturas de m-Salud con unos costes reducidos. El primer bloque define un esquema global que proporciona unos niveles de seguridad e interoperabilidad acordes con las características de las distintas aplicaciones de m-Salud. Este esquema está compuesto por tres capas diferenciadas, diseñadas a la medidas de los dominios de m-Salud y de sus restricciones, incluyendo medidas de seguridad adecuadas para la defensa contra las amenazas asociadas a sus aplicaciones de m-Salud. El segundo bloque establece la extensión de seguridad de aquellos protocolos estándar que permiten la adquisición, el intercambio y/o la administración de información biomédica -- por tanto, usados por muchas aplicaciones de m-Salud -- pero no reúnen los niveles de seguridad detallados en el esquema previo. Estas extensiones se concretan para los estándares biomédicos ISO/IEEE 11073 PHD y SCP-ECG. El tercer bloque propone nuevas formas de fortalecer la seguridad de los tests biomédicos, que constituyen el elemento esencial de muchas aplicaciones de m-Salud de carácter clínico, mediante codificaciones novedosas. Finalmente el cuarto bloque, que se sitúa en paralelo a los anteriores, selecciona herramientas genéricas de seguridad (elementos de autenticación y criptográficos) cuya integración en los otros bloques resulta idónea, y desarrolla nuevas herramientas de seguridad, basadas en señal -- embedding y keytagging --, para reforzar la protección de los test biomédicos.The paradigm of m-Health (mobile health) advocates for the massive integration of advanced mobile communications, network and sensor technologies in healthcare applications and systems to foster the deployment of a new, user/patient-centered healthcare model enabling the empowerment of users in the management of their health (e.g. by increasing their health literacy, promoting healthy lifestyles and the prevention of diseases), a better home-based healthcare delivery for elderly and chronic patients and important savings for healthcare systems due to the reduction of hospitalizations in number and duration. It is a fact that many m-Health applications demand high availability of biomedical information from their users (for further accurate analysis, e.g. by fusion of various signals) to guarantee high quality of service, which on the other hand entails increasing the potential surfaces for attacks. Therefore, it is not surprising that security (and privacy) is commonly included among the most important barriers for the success of m-Health. As a non-functional requirement for m-Health applications, security has received less attention than other technical issues that were more pressing at earlier development stages, such as reliability, eficiency, interoperability or usability. Another fact that has contributed to delaying the enforcement of robust security policies is that guaranteeing a certain security level implies costs that can be very relevant and that span along diferent dimensions. These include budgeting (e.g. the demand of extra hardware for user authentication), performance (e.g. lower eficiency and interoperability due to the addition of security elements) and usability (e.g. cumbersome configuration of devices and applications due to security options). Therefore, security solutions that aim to satisfy all the stakeholders in the m-Health context (users/patients, medical staff, technical staff, systems and devices manufacturers, regulators, etc.) shall be robust and, at the same time, minimize their associated costs. This Thesis details a proposal, composed of four interrelated blocks, to integrate appropriate levels of security in m-Health architectures in a cost-efcient manner. The first block designes a global scheme that provides different security and interoperability levels accordingto how critical are the m-Health applications to be implemented. This consists ofthree layers tailored to the m-Health domains and their constraints, whose security countermeasures defend against the threats of their associated m-Health applications. Next, the second block addresses the security extension of those standard protocols that enable the acquisition, exchange and/or management of biomedical information | thus, used by many m-Health applications | but do not meet the security levels described in the former scheme. These extensions are materialized for the biomedical standards ISO/IEEE 11073 PHD and SCP-ECG. Then, the third block proposes new ways of enhancing the security of biomedical standards, which are the centerpiece of many clinical m-Health applications, by means of novel codings. Finally the fourth block, with is parallel to the others, selects generic security methods (for user authentication and cryptographic protection) whose integration in the other blocks results optimal, and also develops novel signal-based methods (embedding and keytagging) for strengthening the security of biomedical tests. The layer-based extensions of the standards ISO/IEEE 11073 PHD and SCP-ECG can be considered as robust, cost-eficient and respectful with their original features and contents. The former adds no attributes to its data information model, four new frames to the service model |and extends four with new sub-frames|, and only one new sub-state to the communication model. Furthermore, a lightweight architecture consisting of a personal health device mounting a 9 MHz processor and an aggregator mounting a 1 GHz processor is enough to transmit a 3-lead electrocardiogram in real-time implementing the top security layer. The extra requirements associated to this extension are an initial configuration of the health device and the aggregator, tokens for identification/authentication of users if these devices are to be shared and the implementation of certain IHE profiles in the aggregator to enable the integration of measurements in healthcare systems. As regards to the extension of SCP-ECG, it only adds a new section with selected security elements and syntax in order to protect the rest of file contents and provide proper role-based access control. The overhead introduced in the protected SCP-ECG is typically 2{13 % of the regular file size, and the extra delays to protect a newly generated SCP-ECG file and to access it for interpretation are respectively a 2{10 % and a 5 % of the regular delays. As regards to the signal-based security techniques developed, the embedding method is the basis for the proposal of a generic coding for tests composed of biomedical signals, periodic measurements and contextual information. This has been adjusted and evaluated with electrocardiogram and electroencephalogram-based tests, proving the objective clinical quality of the coded tests, the capacity of the coding-access system to operate in real-time (overall delays of 2 s for electrocardiograms and 3.3 s for electroencephalograms) and its high usability. Despite of the embedding of security and metadata to enable m-Health services, the compression ratios obtained by this coding range from ' 3 in real-time transmission to ' 5 in offline operation. Complementarily, keytagging permits associating information to images (and other signals) by means of keys in a secure and non-distorting fashion, which has been availed to implement security measures such as image authentication, integrity control and location of tampered areas, private captioning with role-based access control, traceability and copyright protection. The tests conducted indicate a remarkable robustness-capacity tradeoff that permits implementing all this measures simultaneously, and the compatibility of keytagging with JPEG2000 compression, maintaining this tradeoff while setting the overall keytagging delay in only ' 120 ms for any image size | evidencing the scalability of this technique. As a general conclusion, it has been demonstrated and illustrated with examples that there are various, complementary and structured manners to contribute in the implementation of suitable security levels for m-Health architectures with a moderate cost in budget, performance, interoperability and usability. The m-Health landscape is evolving permanently along all their dimensions, and this Thesis aims to do so with its security. Furthermore, the lessons learned herein may offer further guidance for the elaboration of more comprehensive and updated security schemes, for the extension of other biomedical standards featuring low emphasis on security or privacy, and for the improvement of the state of the art regarding signal-based protection methods and applications

JPEG-like Image Compression using Neural-network-based Block Classification and Adaptive Reordering of Transform Coefficients

The research described in this thesis addresses aspects of coding of discrete-cosinetransform (DCT) coefficients, that are present in a variety of transform-based digital-image-compression schemes such as JPEG. Coefficient reordering; that directly affects the symbol statistics for entropy coding, and therefore the effectiveness of entropy coding; is investigated. Adaptive zigzag reordering, a novel versatile technique that achieves efficient reordering by processing variable-size rectangular sub-blocks of coefficients, is developed. Classification of blocks of DCT coefficients using an artificial neural network (ANN) prior to adaptive zigzag reordering is also considered. Some established digital-image-compression techniques are reviewed, and the JPEG standard for the DCT-based method is studied in more detail. An introduction to artificial neural networks is provided. Lossless conversion of blocks of coefficients using adaptive zigzag reordering is investigated, and experimental results are presented. A versatile algorithm, that generates zigzag scan paths for sub-blocks of any dimensions using a binary decision tree, is developed. An implementation of the algorithm based on programmable logic devices (PLDs) is described demonstrating the feasibility of hardware implementations. Coding of the sub-block dimensions, that need to be retained in order to reconstruct a sub-block during decoding, based on the scan-path length is developed. Lossy conversion of blocks of coefficients is also considered, and experimental results are presented. A two-layer feedforward artificial neural network trained using an error-backpropagation algorithm, that determines the sub-block dimensions, is described. Isolated nonzero coefficients of small significance are discarded in some blocks, and therefore smaller sub-blocks are generated

Approximate and timing-speculative hardware design for high-performance and energy-efficient video processing

Since the end of transistor scaling in 2-D appeared on the horizon, innovative circuit design paradigms have been on the rise to go beyond the well-established and ultraconservative exact computing. Many compute-intensive applications – such as video processing – exhibit an intrinsic error resilience and do not necessarily require perfect accuracy in their numerical operations. Approximate computing (AxC) is emerging as a design alternative to improve the performance and energy-efficiency requirements for many applications by trading its intrinsic error tolerance with algorithm and circuit efficiency. Exact computing also imposes a worst-case timing to the conventional design of hardware accelerators to ensure reliability, leading to an efficiency loss. Conversely, the timing-speculative (TS) hardware design paradigm allows increasing the frequency or decreasing the voltage beyond the limits determined by static timing analysis (STA), thereby narrowing pessimistic safety margins that conventional design methods implement to prevent hardware timing errors. Timing errors should be evaluated by an accurate gate-level simulation, but a significant gap remains: How these timing errors propagate from the underlying hardware all the way up to the entire algorithm behavior, where they just may degrade the performance and quality of service of the application at stake? This thesis tackles this issue by developing and demonstrating a cross-layer framework capable of performing investigations of both AxC (i.e., from approximate arithmetic operators, approximate synthesis, gate-level pruning) and TS hardware design (i.e., from voltage over-scaling, frequency over-clocking, temperature rising, and device aging). The cross-layer framework can simulate both timing errors and logic errors at the gate-level by crossing them dynamically, linking the hardware result with the algorithm-level, and vice versa during the evolution of the application’s runtime. Existing frameworks perform investigations of AxC and TS techniques at circuit-level (i.e., at the output of the accelerator) agnostic to the ultimate impact at the application level (i.e., where the impact is truly manifested), leading to less optimization. Unlike state of the art, the framework proposed offers a holistic approach to assessing the tradeoff of AxC and TS techniques at the application-level. This framework maximizes energy efficiency and performance by identifying the maximum approximation levels at the application level to fulfill the required good enough quality. This thesis evaluates the framework with an 8-way SAD (Sum of Absolute Differences) hardware accelerator operating into an HEVC encoder as a case study. Application-level results showed that the SAD based on the approximate adders achieve savings of up to 45% of energy/operation with an increase of only 1.9% in BD-BR. On the other hand, VOS (Voltage Over-Scaling) applied to the SAD generates savings of up to 16.5% in energy/operation with around 6% of increase in BD-BR. The framework also reveals that the boost of about 6.96% (at 50°) to 17.41% (at 75° with 10- Y aging) in the maximum clock frequency achieved with TS hardware design is totally lost by the processing overhead from 8.06% to 46.96% when choosing an unreliable algorithm to the blocking match algorithm (BMA). We also show that the overhead can be avoided by adopting a reliable BMA. This thesis also shows approximate DTT (Discrete Tchebichef Transform) hardware proposals by exploring a transform matrix approximation, truncation and pruning. The results show that the approximate DTT hardware proposal increases the maximum frequency up to 64%, minimizes the circuit area in up to 43.6%, and saves up to 65.4% in power dissipation. The DTT proposal mapped for FPGA shows an increase of up to 58.9% on the maximum frequency and savings of about 28.7% and 32.2% on slices and dynamic power, respectively compared with stat

Entropy in Image Analysis II

Image analysis is a fundamental task for any application where extracting information from images is required. The analysis requires highly sophisticated numerical and analytical methods, particularly for those applications in medicine, security, and other fields where the results of the processing consist of data of vital importance. This fact is evident from all the articles composing the Special Issue "Entropy in Image Analysis II", in which the authors used widely tested methods to verify their results. In the process of reading the present volume, the reader will appreciate the richness of their methods and applications, in particular for medical imaging and image security, and a remarkable cross-fertilization among the proposed research areas

Wearable Wireless Devices

No abstract available