19,065 research outputs found

    Regional differences in childhood BMI data : the Malta childhood national body mass index study

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    Introduction: Obesity is a problem of major public health concern all over the world and Malta has high obesity prevalence rates. With over a third of Maltese children being overweight or obese, the Malta Childhood National Body Mass Index study was devised to quantify the extent of the problem precisely. This paper looks at regional differences in the BMI data obtained. Methods: Training in measurement was provided to physical education teachers and identical stadiometers were used. Data was processed using World Health Organisation cut-offs for underweight, overweight and obesity. Results: A total of 41,343 students from 145 schools were measured. Age range from 4.7 to 17 years. Approximately 40% of school-aged children in Malta were overweight or obese, with higher percentages of obesity than overweight being observed. Results show significant differences in BMI between children living in Northern and Southern regions of Malta. Conclusion: Results from this study further confirm the high levels of overweight and obesity in Maltese children. The North-South differences should help better target public health resources and should be further evaluated in more focussed research.peer-reviewe

    The Members Speak: A Summary of the ARES Membership Survey Report

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    Most respondents to the survey indicated a high level of satisfaction with the current activities of ARES, while some members offered suggestions to improve the organization. Much of the data and other comments produced by the survey have been incorporated into various parts of the current Strategic Plan.

    Beyond Scope of Practice: Inferring High School Tennis Coaches' Behavior from their Nutrition and Eating Disorder Knowledge

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    The primary purpose of this study was to assess high school tennis coaches’ knowledge of macronutrients and disordered eating (e.g., etiology). Other purposes included identifying confidence in knowledge and any differences between the participating coaches’ knowledge and demographic variables. To address these purposes, the 27-question Nutrition and Eating Disorders in Tennis (“NET”) Survey was created. The study design involved a one-time voluntary assessment of the Indiana coaches’ demographic variables, knowledge, sources of knowledge, and level of confidence (e.g., Not At All or Very Confident). Overall, the results revealed that the coaches lacked knowledge. The average score was 70.6%, which was below the criterion for adequate knowledge. Furthermore, the coaches lacked adequate knowledge in three of the five knowledge domains: Treatment and Prevention of Disordered Eating (63.6% ± 22.9%), Disordered Eating Signs and Symptoms (60.0% ± 21.7%), and Macronutrients (57.0% ± 22.4%). There were no significant differences between coaches’ education level, gender, or type and knowledge. However, there was in experience; the more years coached, the lower the scores. Finally, there was a trend of overconfidence in answers

    Are the East Asian Currencies still Misaligned? An Analysis Based on Absolute PPP-Income Relationship using Panel Data

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    Over 10 years after the currency crisis, the degree of exchange rate misalignment is still an issue of contention for East Asian countries. This study evaluates the degrees of currency misalignment of Korea, China, Malaysia, Thailand, the Phillipines, and Indonesia by examining absolute purchasing power parity (PPP)-income relationships using panel data. The distinction between local currency misalignments and the US dollar misalignment is stressed. The estimated misalignments in 2007 were 22.4 per cent overvaluation for the Indonesian rupiah, 12.5 per cent overvaluation for the Philippine peso, and 15.6 per cent undervaluation for the Malaysian ringgit.currency, ppp-income, panel data

    Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up.

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    BackgroundNovel second-line treatments are needed for patients with advanced urothelial cancer (UC). Interim analysis of the phase III KEYNOTE-045 study showed a superior overall survival (OS) benefit of pembrolizumab, a programmed death 1 inhibitor, versus chemotherapy in patients with advanced UC that progressed on platinum-based chemotherapy. Here we report the long-term safety and efficacy outcomes of KEYNOTE-045.Patients and methodsAdult patients with histologically/cytologically confirmed UC whose disease progressed after first-line, platinum-containing chemotherapy were enrolled. Patients were randomly assigned 1 : 1 to receive pembrolizumab [200 mg every 3 weeks (Q3W)] or investigator's choice of paclitaxel (175 mg/m2 Q3W), docetaxel (75 mg/m2 Q3W), or vinflunine (320 mg/m2 Q3W). Primary end points were OS and progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors, version 1.1 (RECIST v1.1) by blinded independent central radiology review (BICR). A key secondary end point was objective response rate per RECIST v1.1 by BICR.ResultsA total of 542 patients were enrolled (pembrolizumab, n = 270; chemotherapy, n = 272). Median follow-up as of 26 October 2017 was 27.7 months. Median 1- and 2-year OS rates were higher with pembrolizumab (44.2% and 26.9%, respectively) than chemotherapy (29.8% and 14.3%, respectively). PFS rates did not differ between treatment arms; however, 1- and 2-year PFS rates were higher with pembrolizumab. The objective response rate was also higher with pembrolizumab (21.1% versus 11.0%). Median duration of response to pembrolizumab was not reached (range 1.6+ to 30.0+ months) versus chemotherapy (4.4 months; range 1.4+ to 29.9+ months). Pembrolizumab had lower rates of any grade (62.0% versus 90.6%) and grade ≄3 (16.5% versus 50.2%) treatment-related adverse events than chemotherapy.ConclusionsLong-term results (>2 years' follow-up) were consistent with those of previously reported analyses, demonstrating continued clinical benefit of pembrolizumab over chemotherapy for efficacy and safety for treatment of locally advanced/metastatic, platinum-refractory UC.Trial registrationClinicalTrials.gov: NCT02256436

    Cities in Crisis: A Special Analytic Report on High School Graduation

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    Examines graduation-rate patterns in the fifty most populous U.S. cities and surrounding metropolitan areas. Compares data by race/ethnicity, gender, and principal district, and highlights the urban-suburban gaps within the same metropolitan areas

    Medicaid's Future: What Might ACA Repeal Mean?

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    Issue: Republicans in Congress are expected to repeal portions of the Affordable Care Act (ACA) using a fast-track process known as budget reconciliation.Goals: This issue brief examines how repeal legislation could affect Medicaid, the nation's health care safety net, which insured 70 million people in 2016.Findings and Conclusions: Partial-repeal legislation that passed Congress but was vetoed by President Obama in 2016 offers some insight but new legislation could go further. It could repeal the ACA's Medicaid eligibility expansions for adults and children but also roll back other provisions, such as simplified enrollment and improvements in long-term services and supports for beneficiaries with disabilities. Additionally, the Trump Administration could expand use of demonstration authority to introduce deeper structural changes into Medicaid, such as eligibility restrictions tied to work, required premium contributions and lock-out for nonpayment, annual enrollment periods, and coverage limits and exclusions. Together, these changes would have far-reaching implications for Medicaid's continued role as the nation's safety-net insurer

    Go crowdfund yourself: some unintended consequences of crowdfunding for documentary film and industry in the U.K.

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    Realizing Health Reform's Potential: Will the Affordable Care Act Make Health Insurance Affordable?

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    Examines the percentage of low-income families, by income, family structure, and out-of-pocket healthcare costs, unable to afford insurance even with the premium and cost-sharing subsidies provided under the 2010 reform. Explores implications
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