Real-time classification technique for early detection and prevention of myocardial infarction on wearable devices

Continuous monitoring of patients suffering from cardiovascular diseases and, in particular, myocardial infarction (MI) places a considerable burden on health-care systems and government budgets. The rise of wearable devices alleviates this burden, allowing for long-term patient monitoring in ambulatory settings. One of the major challenges in this area is to design ultra-low energy wearable devices for long-term monitoring of patients’ vital signs. In this work, we present a real-time event-driven classification technique, based on support vector machines (SVM) and statistical outlier detection. The main goal of this technique is to maintain a high classification accuracy while reducing the complexity of the classification algorithm. This technique leads to a reduction in energy consumption and thus battery lifetime extension. We validate our approach on a well-established and complete myocardial infarction (MI) database (Physiobank, PTB Diagnostic ECG database [1]). Our experimental evaluation demonstrates that our real-time classification scheme outperforms the existing approaches in terms of energy consumption and battery lifetime by a factor of 3, while maintaining the classification accuracy at a medically-acceptable level of 90%

Computational Intelligence in Healthcare

The number of patient health data has been estimated to have reached 2314 exabytes by 2020. Traditional data analysis techniques are unsuitable to extract useful information from such a vast quantity of data. Thus, intelligent data analysis methods combining human expertise and computational models for accurate and in-depth data analysis are necessary. The technological revolution and medical advances made by combining vast quantities of available data, cloud computing services, and AI-based solutions can provide expert insight and analysis on a mass scale and at a relatively low cost. Computational intelligence (CI) methods, such as fuzzy models, artificial neural networks, evolutionary algorithms, and probabilistic methods, have recently emerged as promising tools for the development and application of intelligent systems in healthcare practice. CI-based systems can learn from data and evolve according to changes in the environments by taking into account the uncertainty characterizing health data, including omics data, clinical data, sensor, and imaging data. The use of CI in healthcare can improve the processing of such data to develop intelligent solutions for prevention, diagnosis, treatment, and follow-up, as well as for the analysis of administrative processes. The present Special Issue on computational intelligence for healthcare is intended to show the potential and the practical impacts of CI techniques in challenging healthcare applications

HEAL-WEAR: an Ultra-Low Power Heterogeneous System for Bio-Signal Analysis

Personalized healthcare devices enable low-cost, unobtrusive and long-term acquisition of clinically-relevant biosignals. These appliances, termed Wireless Body Sensor Nodes (WBSNs), are fostering a revolution in health monitoring for patients affected by chronic ailments. Nowadays, WBSNs often embed complex digital processing routines, which must be performed within an extremely tight energy budget. Addressing this challenge, in this paper we introduce a novel computing architecture devoted to the ultra-low power analysis of biosignals. Its heterogeneous structure comprises multiple processors interfaced with a shared acceleration resource, implemented as a Coarse Grained Reconfigurable Array (CGRA). The CGRA mesh effectively supports the execution of the intensive loops that characterize bio-signal analysis applications, while requiring a low reconfiguration overhead. Moreover, both the processors and the reconfigurable fabric feature Single-Instruction / Multiple- Data (SIMD) execution modes, which increase efficiency when multiple data streams are concurrently processed. The run-time behavior on the system is orchestrated by a light-weight hardware mechanism, which concurrently synchronizes processors for SIMD execution and regulates access to the reconfigurable accelerator. By jointly leveraging run-time reconfiguration and SIMD execution, the illustrated heterogeneous system achieves, when executing complex bio-signal analysis applications, speedups of up to 11.3x on the considered kernels and up to 37.2% overall energy savings, with respect to an ultra-low power multicore platform which does not feature CGRA acceleration

Wearable and Nearable Biosensors and Systems for Healthcare

Biosensors and systems in the form of wearables and “nearables” (i.e., everyday sensorized objects with transmitting capabilities such as smartphones) are rapidly evolving for use in healthcare. Unlike conventional approaches, these technologies can enable seamless or on-demand physiological monitoring, anytime and anywhere. Such monitoring can help transform healthcare from the current reactive, one-size-fits-all, hospital-centered approach into a future proactive, personalized, decentralized structure. Wearable and nearable biosensors and systems have been made possible through integrated innovations in sensor design, electronics, data transmission, power management, and signal processing. Although much progress has been made in this field, many open challenges for the scientific community remain, especially for those applications requiring high accuracy. This book contains the 12 papers that constituted a recent Special Issue of Sensors sharing the same title. The aim of the initiative was to provide a collection of state-of-the-art investigations on wearables and nearables, in order to stimulate technological advances and the use of the technology to benefit healthcare. The topics covered by the book offer both depth and breadth pertaining to wearable and nearable technology. They include new biosensors and data transmission techniques, studies on accelerometers, signal processing, and cardiovascular monitoring, clinical applications, and validation of commercial devices

Data-driven methods for analyzing ballistocardiograms in longitudinal cardiovascular monitoring

Cardiovascular disease (CVD) is the leading cause of death in the US; about 48% of American adults have one or more types of CVD. The importance of continuous monitoring of the older population, for early detection of changes in health conditions, has been shown in the literature, as the key to a successful clinical intervention. We have been investigating environmentally-embedded in-home networks of non-invasive sensing modalities. This dissertation concentrates on the signal processing techniques required for the robust extraction of morphological features from the ballistocardiographs (BCG), and machine learning approaches to utilize these features in non-invasive monitoring of cardiovascular conditions. At first, enhancements in the time domain detection of the cardiac cycle are addressed due to its importance in the estimation of heart rate variability (HRV) and sleep stages. The proposed enhancements in the energy-based algorithm for BCG beat detection have shown at least 50% improvement in the root mean square error (RMSE) of the beat to beat heart rate estimations compared to the reference estimations from the electrocardiogram (ECG) R to R intervals. These results are still subject to some errors, primarily due to the contamination of noise and motion artifacts caused by floor vibration, unconstrained subject movements, or even the respiratory activities. Aging, diseases, breathing, and sleep disorders can also affect the quality of estimation as they slightly modify the morphology of the BCG waveform.Includes bibliographical reference