1,716 research outputs found
Distributed simulation of building systems for legacy software reuse
The use of integrated building performance simulation can substantially help in improving a building design with regards to comfort levels and fuel consumption, while reducing emission of greenhouse gasses. However, the traditional tools that are closed for inter-communication, limit the modeler to use of components only available within that particular package. This paper gives an overview of distributed simulation approach that can alleviate above limitation. Each program can represent only a part of a building system that is able to model, exchanging the necessary information during the execution and bridging the gaps between the tools. Several important issues closely connected with its implementation, such as synchronization, are pointed out, and the sensitivity of a model on different coupling strategies is studied. The paper concludes with highlighting the gained flexibility in modeling and simulation of building performance that arises from the distributed approach
Assessing and augmenting SCADA cyber security: a survey of techniques
SCADA systems monitor and control critical infrastructures of national importance such as power generation and distribution, water supply, transportation networks, and manufacturing facilities. The pervasiveness, miniaturisations and declining costs of internet connectivity have transformed these systems from strictly isolated to highly interconnected networks. The connectivity provides immense benefits such as reliability, scalability and remote connectivity, but at the same time exposes an otherwise isolated and secure system, to global cyber security threats. This inevitable transformation to highly connected systems thus necessitates effective security safeguards to be in place as any compromise or downtime of SCADA systems can have severe economic, safety and security ramifications. One way to ensure vital asset protection is to adopt a viewpoint similar to an attacker to determine weaknesses and loopholes in defences. Such mind sets help to identify and fix potential breaches before their exploitation. This paper surveys tools and techniques to uncover SCADA system vulnerabilities. A comprehensive review of the selected approaches is provided along with their applicability
Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity
Background:
MHC Class I molecules present antigenic peptides to cytotoxic T cells, which forms an integral part of the adaptive immune response. Peptides are bound within a groove formed by the MHC heavy chain. Previous approaches to MHC Class I-peptide binding prediction have largely concentrated on the peptide anchor residues located at the P2 and C-terminus positions.
Results:
A large dataset comprising MHC-peptide structural complexes was created by re-modelling pre-determined x-ray crystallographic structures. Static energetic analysis, following energy minimisation, was performed on the dataset in order to characterise interactions between bound peptides and the MHC Class I molecule, partitioning the interactions within the groove into van der Waals, electrostatic and total non-bonded energy contributions.
Conclusion:
The QSAR techniques of Genetic Function Approximation (GFA) and Genetic Partial Least Squares (G/PLS) algorithms were used to identify key interactions between the two molecules by comparing the calculated energy values with experimentally-determined BL50 data. Although the peptide termini binding interactions help ensure the stability of the MHC Class I-peptide complex, the central region of the peptide is also important in defining the specificity of the interaction. As thermodynamic studies indicate that peptide association and dissociation may be driven entropically, it may be necessary to incorporate entropic contributions into future calculations
Future Perspectives of Co-Simulation in the Smart Grid Domain
The recent attention towards research and development in cyber-physical
energy systems has introduced the necessity of emerging multi-domain
co-simulation tools. Different educational, research and industrial efforts
have been set to tackle the co-simulation topic from several perspectives. The
majority of previous works has addressed the standardization of models and
interfaces for data exchange, automation of simulation, as well as improving
performance and accuracy of co-simulation setups. Furthermore, the domains of
interest so far have involved communication, control, markets and the
environment in addition to physical energy systems. However, the current
characteristics and state of co-simulation testbeds need to be re-evaluated for
future research demands. These demands vary from new domains of interest, such
as human and social behavior models, to new applications of co-simulation, such
as holistic prognosis and system planning. This paper aims to formulate these
research demands that can then be used as a road map and guideline for future
development of co-simulation in cyber-physical energy systems
A multiphysics and multiscale software environment for modeling astrophysical systems
We present MUSE, a software framework for combining existing computational
tools for different astrophysical domains into a single multiphysics,
multiscale application. MUSE facilitates the coupling of existing codes written
in different languages by providing inter-language tools and by specifying an
interface between each module and the framework that represents a balance
between generality and computational efficiency. This approach allows
scientists to use combinations of codes to solve highly-coupled problems
without the need to write new codes for other domains or significantly alter
their existing codes. MUSE currently incorporates the domains of stellar
dynamics, stellar evolution and stellar hydrodynamics for studying generalized
stellar systems. We have now reached a "Noah's Ark" milestone, with (at least)
two available numerical solvers for each domain. MUSE can treat multi-scale and
multi-physics systems in which the time- and size-scales are well separated,
like simulating the evolution of planetary systems, small stellar associations,
dense stellar clusters, galaxies and galactic nuclei.
In this paper we describe three examples calculated using MUSE: the merger of
two galaxies, the merger of two evolving stars, and a hybrid N-body simulation.
In addition, we demonstrate an implementation of MUSE on a distributed computer
which may also include special-purpose hardware, such as GRAPEs or GPUs, to
accelerate computations. The current MUSE code base is publicly available as
open source at http://muse.liComment: 24 pages, To appear in New Astronomy Source code available at
http://muse.l
An Open Architecture Framework for Electronic Warfare Based Approach to HLA Federate Development
A variety of electronic warfare models are developed in the Electronic Warfare Research Center. An Open Architecture Framework for Electronic Warfare (OAFEw) has been developed for reusability of various object models participating in the electronic warfare simulation and for extensibility of the electronic warfare simulator. OAFEw is a kind of component-based software (SW) lifecycle management support framework. This OAFEw is defined by six components and ten rules. The purpose of this study is to construct a Distributed Simulation Interface Model, according to the rules of OAFEw, and create Use Case Model of OAFEw Reference Conceptual Model version 1.0. This is embodied in the OAFEw-FOM (Federate Object Model) for High-Level Architecture (HLA) based distributed simulation. Therefore, we design and implement EW real-time distributed simulation that can work with a model in C++ and MATLAB API (Application Programming Interface). In addition, OAFEw-FOM, electronic component model, and scenario of the electronic warfare domain were designed through simple scenarios for verification, and real-time distributed simulation between C++ and MATLAB was performed through OAFEw-Distributed Simulation Interface
Federated Simulation and Gaming Framework for a Decentralized Space-Based Resource Economy
Future human space exploration will require large amounts of resources for shielding and building materials, propellants, and consumables. A space-based resource economy could produce, transport, and store resource at distributed locations such as the lunar surface, stable orbits, or Lagrange points to avoid Earth's deep gravity well. Design challenges include decentralized operation and management and socio-technical complexities not commonly addressed by modeling and simulation methods. This paper seeks to tackle these challenges by applying aspects of military wargaming to promote effective communication between decision-makers. A software architecture for federated simulation based on IEEE-1516 (HLA-Evolved) is presented in the context of multiple lunar in-situ resource production processes, resource depots, and intermediate transportation. The federation-level framework identifies interfaces between simulation models (federates), focusing on persistent assets (elements) and resources exchanged. Future work will develop the federated resource economy model and evaluate with decision-makers playing the roles of competing and collaborating players.United States. Dept. of DefenseUnited States. Air Force Office of Scientific ResearchAmerican Society for Engineering Education. National Defense Science and Engineering Graduate Fellowship (32 CFR 168a
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