16,047 research outputs found
MOLNs: A cloud platform for interactive, reproducible and scalable spatial stochastic computational experiments in systems biology using PyURDME
Computational experiments using spatial stochastic simulations have led to
important new biological insights, but they require specialized tools, a
complex software stack, as well as large and scalable compute and data analysis
resources due to the large computational cost associated with Monte Carlo
computational workflows. The complexity of setting up and managing a
large-scale distributed computation environment to support productive and
reproducible modeling can be prohibitive for practitioners in systems biology.
This results in a barrier to the adoption of spatial stochastic simulation
tools, effectively limiting the type of biological questions addressed by
quantitative modeling. In this paper, we present PyURDME, a new, user-friendly
spatial modeling and simulation package, and MOLNs, a cloud computing appliance
for distributed simulation of stochastic reaction-diffusion models. MOLNs is
based on IPython and provides an interactive programming platform for
development of sharable and reproducible distributed parallel computational
experiments
LEGaTO: first steps towards energy-efficient toolset for heterogeneous computing
LEGaTO is a three-year EU H2020 project which started in December 2017. The LEGaTO project will leverage task-based programming models to provide a software ecosystem for Made-in-Europe heterogeneous hardware composed of CPUs, GPUs, FPGAs and dataflow engines. The aim is to attain one order of magnitude energy savings from the edge to the converged cloud/HPC.Peer ReviewedPostprint (author's final draft
funcX: A Federated Function Serving Fabric for Science
Exploding data volumes and velocities, new computational methods and
platforms, and ubiquitous connectivity demand new approaches to computation in
the sciences. These new approaches must enable computation to be mobile, so
that, for example, it can occur near data, be triggered by events (e.g.,
arrival of new data), be offloaded to specialized accelerators, or run remotely
where resources are available. They also require new design approaches in which
monolithic applications can be decomposed into smaller components, that may in
turn be executed separately and on the most suitable resources. To address
these needs we present funcX---a distributed function as a service (FaaS)
platform that enables flexible, scalable, and high performance remote function
execution. funcX's endpoint software can transform existing clouds, clusters,
and supercomputers into function serving systems, while funcX's cloud-hosted
service provides transparent, secure, and reliable function execution across a
federated ecosystem of endpoints. We motivate the need for funcX with several
scientific case studies, present our prototype design and implementation, show
optimizations that deliver throughput in excess of 1 million functions per
second, and demonstrate, via experiments on two supercomputers, that funcX can
scale to more than more than 130000 concurrent workers.Comment: Accepted to ACM Symposium on High-Performance Parallel and
Distributed Computing (HPDC 2020). arXiv admin note: substantial text overlap
with arXiv:1908.0490
Autonomic Cloud Computing: Open Challenges and Architectural Elements
As Clouds are complex, large-scale, and heterogeneous distributed systems,
management of their resources is a challenging task. They need automated and
integrated intelligent strategies for provisioning of resources to offer
services that are secure, reliable, and cost-efficient. Hence, effective
management of services becomes fundamental in software platforms that
constitute the fabric of computing Clouds. In this direction, this paper
identifies open issues in autonomic resource provisioning and presents
innovative management techniques for supporting SaaS applications hosted on
Clouds. We present a conceptual architecture and early results evidencing the
benefits of autonomic management of Clouds.Comment: 8 pages, 6 figures, conference keynote pape
PaPaS: A Portable, Lightweight, and Generic Framework for Parallel Parameter Studies
The current landscape of scientific research is widely based on modeling and
simulation, typically with complexity in the simulation's flow of execution and
parameterization properties. Execution flows are not necessarily
straightforward since they may need multiple processing tasks and iterations.
Furthermore, parameter and performance studies are common approaches used to
characterize a simulation, often requiring traversal of a large parameter
space. High-performance computers offer practical resources at the expense of
users handling the setup, submission, and management of jobs. This work
presents the design of PaPaS, a portable, lightweight, and generic workflow
framework for conducting parallel parameter and performance studies. Workflows
are defined using parameter files based on keyword-value pairs syntax, thus
removing from the user the overhead of creating complex scripts to manage the
workflow. A parameter set consists of any combination of environment variables,
files, partial file contents, and command line arguments. PaPaS is being
developed in Python 3 with support for distributed parallelization using SSH,
batch systems, and C++ MPI. The PaPaS framework will run as user processes, and
can be used in single/multi-node and multi-tenant computing systems. An example
simulation using the BehaviorSpace tool from NetLogo and a matrix multiply
using OpenMP are presented as parameter and performance studies, respectively.
The results demonstrate that the PaPaS framework offers a simple method for
defining and managing parameter studies, while increasing resource utilization.Comment: 8 pages, 6 figures, PEARC '18: Practice and Experience in Advanced
Research Computing, July 22--26, 2018, Pittsburgh, PA, US
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