4,462 research outputs found

    Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues.

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    The development of new models of biological tissues that consider cells in a discrete manner is becoming increasingly popular as an alternative to continuum methods based on partial differential equations, although formal relationships between the discrete and continuum frameworks remain to be established. For crystal mechanics, the discrete-to-continuum bridge is often made by assuming that local atom displacements can be mapped homogeneously from the mesoscale deformation gradient, an assumption known as the Cauchy-Born rule (CBR). Although the CBR does not hold exactly for noncrystalline materials, it may still be used as a first-order approximation for analytic calculations of effective stresses or strain energies. In this work, our goal is to investigate numerically the applicability of the CBR to two-dimensional cellular-scale models by assessing the mechanical behavior of model biological tissues, including crystalline (honeycomb) and noncrystalline reference states. The numerical procedure involves applying an affine deformation to the boundary cells and computing the quasistatic position of internal cells. The position of internal cells is then compared with the prediction of the CBR and an average deviation is calculated in the strain domain. For center-based cell models, we show that the CBR holds exactly when the deformation gradient is relatively small and the reference stress-free configuration is defined by a honeycomb lattice. We show further that the CBR may be used approximately when the reference state is perturbed from the honeycomb configuration. By contrast, for vertex-based cell models, a similar analysis reveals that the CBR does not provide a good representation of the tissue mechanics, even when the reference configuration is defined by a honeycomb lattice. The paper concludes with a discussion of the implications of these results for concurrent discrete and continuous modeling, adaptation of atom-to-continuum techniques to biological tissues, and model classification

    The Multiscale Morphology Filter: Identifying and Extracting Spatial Patterns in the Galaxy Distribution

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    We present here a new method, MMF, for automatically segmenting cosmic structure into its basic components: clusters, filaments, and walls. Importantly, the segmentation is scale independent, so all structures are identified without prejudice as to their size or shape. The method is ideally suited for extracting catalogues of clusters, walls, and filaments from samples of galaxies in redshift surveys or from particles in cosmological N-body simulations: it makes no prior assumptions about the scale or shape of the structures.}Comment: Replacement with higher resolution figures. 28 pages, 17 figures. For Full Resolution Version see: http://www.astro.rug.nl/~weygaert/tim1publication/miguelmmf.pd

    Alpha, Betti and the Megaparsec Universe: on the Topology of the Cosmic Web

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    We study the topology of the Megaparsec Cosmic Web in terms of the scale-dependent Betti numbers, which formalize the topological information content of the cosmic mass distribution. While the Betti numbers do not fully quantify topology, they extend the information beyond conventional cosmological studies of topology in terms of genus and Euler characteristic. The richer information content of Betti numbers goes along the availability of fast algorithms to compute them. For continuous density fields, we determine the scale-dependence of Betti numbers by invoking the cosmologically familiar filtration of sublevel or superlevel sets defined by density thresholds. For the discrete galaxy distribution, however, the analysis is based on the alpha shapes of the particles. These simplicial complexes constitute an ordered sequence of nested subsets of the Delaunay tessellation, a filtration defined by the scale parameter, α\alpha. As they are homotopy equivalent to the sublevel sets of the distance field, they are an excellent tool for assessing the topological structure of a discrete point distribution. In order to develop an intuitive understanding for the behavior of Betti numbers as a function of α\alpha, and their relation to the morphological patterns in the Cosmic Web, we first study them within the context of simple heuristic Voronoi clustering models. Subsequently, we address the topology of structures emerging in the standard LCDM scenario and in cosmological scenarios with alternative dark energy content. The evolution and scale-dependence of the Betti numbers is shown to reflect the hierarchical evolution of the Cosmic Web and yields a promising measure of cosmological parameters. We also discuss the expected Betti numbers as a function of the density threshold for superlevel sets of a Gaussian random field.Comment: 42 pages, 14 figure

    The Spine of the Cosmic Web

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    We present the SpineWeb framework for the topological analysis of the Cosmic Web and the identification of its walls, filaments and cluster nodes. Based on the watershed segmentation of the cosmic density field, the SpineWeb method invokes the local adjacency properties of the boundaries between the watershed basins to trace the critical points in the density field and the separatrices defined by them. The separatrices are classified into walls and the spine, the network of filaments and nodes in the matter distribution. Testing the method with a heuristic Voronoi model yields outstanding results. Following the discussion of the test results, we apply the SpineWeb method to a set of cosmological N-body simulations. The latter illustrates the potential for studying the structure and dynamics of the Cosmic Web.Comment: Accepted for publication HIGH-RES version: http://skysrv.pha.jhu.edu/~miguel/SpineWeb

    The VOISE Algorithm: a Versatile Tool for Automatic Segmentation of Astronomical Images

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    The auroras on Jupiter and Saturn can be studied with a high sensitivity and resolution by the Hubble Space Telescope (HST) ultraviolet (UV) and far-ultraviolet (FUV) Space Telescope spectrograph (STIS) and Advanced Camera for Surveys (ACS) instruments. We present results of automatic detection and segmentation of Jupiter's auroral emissions as observed by HST ACS instrument with VOronoi Image SEgmentation (VOISE). VOISE is a dynamic algorithm for partitioning the underlying pixel grid of an image into regions according to a prescribed homogeneity criterion. The algorithm consists of an iterative procedure that dynamically constructs a tessellation of the image plane based on a Voronoi Diagram, until the intensity of the underlying image within each region is classified as homogeneous. The computed tessellations allow the extraction of quantitative information about the auroral features such as mean intensity, latitudinal and longitudinal extents and length scales. These outputs thus represent a more automated and objective method of characterising auroral emissions than manual inspection.Comment: 9 pages, 7 figures; accepted for publication in MNRA

    Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues

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    The development of new models of biological tissues that consider cells in a discrete manner is becoming increasingly popular as an alternative to PDE-based continuum methods, although formal relationships between the discrete and continuum frameworks remain to be established. For crystal mechanics, the discrete-to-continuum bridge is often made by assuming that local atom displacements can be mapped homogeneously from the mesoscale deformation gradient, an assumption known as the Cauchy-Born rule (CBR). Although the CBR does not hold exactly for non-crystalline materials, it may still be used as a first order approximation for analytic calculations of effective stresses or strain energies. In this work, our goal is to investigate numerically the applicability of the CBR to 2-D cellular-scale models by assessing the mechanical behaviour of model biological tissues, including crystalline (honeycomb) and non-crystalline reference states. The numerical procedure consists in precribing an affine deformation on the boundary cells and computing the position of internal cells. The position of internal cells is then compared with the prediction of the CBR and an average deviation is calculated in the strain domain. For centre-based models, we show that the CBR holds exactly when the deformation gradient is relatively small and the reference stress-free configuration is defined by a honeycomb lattice. We show further that the CBR may be used approximately when the reference state is perturbed from the honeycomb configuration. By contrast, for vertex-based models, a similar analysis reveals that the CBR does not provide a good representation of the tissue mechanics, even when the reference configuration is defined by a honeycomb lattice. The paper concludes with a discussion of the implications of these results for concurrent discrete/continuous modelling, adaptation of atom-to-continuum (AtC) techniques to biological tissues and model classification

    Green-Schwarz Automorphisms and 6D SCFTs

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    All known interacting 6D superconformal field theories (SCFTs) have a tensor branch which includes anti-chiral two-forms and a corresponding lattice of string charges. Automorphisms of this lattice preserve the Dirac pairing and specify discrete global and gauge symmetries of the 6D theory. In this paper we compute this automorphism group for 6D SCFTs. This discrete data determines the geometric structure of the moduli space of vacua. Upon compactification, these automorphisms generate Seiberg-like dualities, as well as additional theories in discrete quotients by the 6D global symmetries. When a perturbative realization is available, these discrete quotients correspond to including additional orientifold planes in the string construction.Comment: v2: 66 pages, 5 figures, updated references and clarifications adde

    The persistent cosmic web and its filamentary structure I: Theory and implementation

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    We present DisPerSE, a novel approach to the coherent multi-scale identification of all types of astrophysical structures, and in particular the filaments, in the large scale distribution of matter in the Universe. This method and corresponding piece of software allows a genuinely scale free and parameter free identification of the voids, walls, filaments, clusters and their configuration within the cosmic web, directly from the discrete distribution of particles in N-body simulations or galaxies in sparse observational catalogues. To achieve that goal, the method works directly over the Delaunay tessellation of the discrete sample and uses the DTFE density computed at each tracer particle; no further sampling, smoothing or processing of the density field is required. The idea is based on recent advances in distinct sub-domains of computational topology, which allows a rigorous application of topological principles to astrophysical data sets, taking into account uncertainties and Poisson noise. Practically, the user can define a given persistence level in terms of robustness with respect to noise (defined as a "number of sigmas") and the algorithm returns the structures with the corresponding significance as sets of critical points, lines, surfaces and volumes corresponding to the clusters, filaments, walls and voids; filaments, connected at cluster nodes, crawling along the edges of walls bounding the voids. The method is also interesting as it allows for a robust quantification of the topological properties of a discrete distribution in terms of Betti numbers or Euler characteristics, without having to resort to smoothing or having to define a particular scale. In this paper, we introduce the necessary mathematical background and describe the method and implementation, while we address the application to 3D simulated and observed data sets to the companion paper.Comment: A higher resolution version is available at http://www.iap.fr/users/sousbie together with complementary material. Submitted to MNRA
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