Mathematical models of avascular cancer

This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative models in greater detail. In the latter part of the review, some possible future avenues of mathematical modelling of avascular tumour development are outlined together with a list of key questions

Distributed Lagrange Multiplier/Fictitious Domain Finite Element Method for a Transient Stokes Interface Problem with Jump Coefficients

The distributed Lagrange multiplier/fictitious domain (DLM/FD)-mixed finite element method is developed and analyzed in this paper for a transient Stokes interface problem with jump coefficients. The semi- and fully discrete DLM/FD-mixed finite element scheme are developed for the first time for this problem with a moving interface, where the arbitrary Lagrangian-Eulerian (ALE) technique is employed to deal with the moving and immersed subdomain. Stability and optimal convergence properties are obtained for both schemes. Numerical experiments are carried out for different scenarios of jump coefficients, and all theoretical results are validated