17,750 research outputs found
Model misspecification in peaks over threshold analysis
Classical peaks over threshold analysis is widely used for statistical
modeling of sample extremes, and can be supplemented by a model for the sizes
of clusters of exceedances. Under mild conditions a compound Poisson process
model allows the estimation of the marginal distribution of threshold
exceedances and of the mean cluster size, but requires the choice of a
threshold and of a run parameter, , that determines how exceedances are
declustered. We extend a class of estimators of the reciprocal mean cluster
size, known as the extremal index, establish consistency and asymptotic
normality, and use the compound Poisson process to derive misspecification
tests of model validity and of the choice of run parameter and threshold.
Simulated examples and real data on temperatures and rainfall illustrate the
ideas, both for estimating the extremal index in nonstandard situations and for
assessing the validity of extremal models.Comment: Published in at http://dx.doi.org/10.1214/09-AOAS292 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
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Patterns of spatial genetic structures in Aedes albopictus (Diptera: Culicidae) populations in China.
BACKGROUND:The Asian tiger mosquito, Aedes albopictus, is one of the 100 worst invasive species in the world and the vector for several arboviruses including dengue, Zika and chikungunya viruses. Understanding the population spatial genetic structure, migration, and gene flow of vector species is critical to effectively preventing and controlling vector-borne diseases. Little is known about the population structure and genetic differentiation of native Ae. albopictus in China. The aim of this study was to examine the patterns of the spatial genetic structures of native Ae. albopictus populations, and their relationship to dengue incidence, on a large geographical scale. METHODS:During 2016-2018, adult female Ae. albopictus mosquitoes were collected by human landing catch (HLC) or human-bait sweep-net collections in 34 localities across China. Thirteen microsatellite markers were used to examine the patterns of genetic diversity, population structure, and gene flow among native Ae. albopictus populations. The correlation between population genetic indices and dengue incidence was also examined. RESULTS:A total of 153 distinct alleles were identified at the 13 microsatellite loci in the tested populations. All loci were polymorphic, with the number of distinct alleles ranging from eight to sixteen. Genetic parameters such as PIC, heterozygosity, allelic richness and fixation index (FST) revealed highly polymorphic markers, high genetic diversity, and low population genetic differentiation. In addition, Bayesian analysis of population structure showed two distinct genetic groups in southern-western and eastern-central-northern China. The Mantel test indicated a positive correlation between genetic distance and geographical distance (R2Â =Â 0.245, PÂ =Â 0.01). STRUCTURE analysis, PCoA and GLS interpolation analysis indicated that Ae. albopictus populations in China were regionally clustered. Gene flow and relatedness estimates were generally high between populations. We observed no correlation between population genetic indices of microsatellite loci in Ae. albopictus populations and dengue incidence. CONCLUSION:Strong gene flow probably assisted by human activities inhibited population differentiation and promoted genetic diversity among populations of Ae. albopictus. This may represent a potential risk of rapid spread of mosquito-borne diseases. The spatial genetic structure, coupled with the association between genetic indices and dengue incidence, may have important implications for understanding the epidemiology, prevention, and control of vector-borne diseases
Weathering the Storm of Business Climate Rankings
This paper explores current usage of the term business climate. It discusses multiple definitions and measures of what constitutes a region's business climate. It also examines how usage of the term varies over time and geography. Finally, it addresses some issues related to business climate rankings, their role in economic development policy, and whether the multiplicity of published state rankings contribute consensus or confusion to the meaning of the term business climate.
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