1,338 research outputs found
Invariance of visual operations at the level of receptive fields
Receptive field profiles registered by cell recordings have shown that
mammalian vision has developed receptive fields tuned to different sizes and
orientations in the image domain as well as to different image velocities in
space-time. This article presents a theoretical model by which families of
idealized receptive field profiles can be derived mathematically from a small
set of basic assumptions that correspond to structural properties of the
environment. The article also presents a theory for how basic invariance
properties to variations in scale, viewing direction and relative motion can be
obtained from the output of such receptive fields, using complementary
selection mechanisms that operate over the output of families of receptive
fields tuned to different parameters. Thereby, the theory shows how basic
invariance properties of a visual system can be obtained already at the level
of receptive fields, and we can explain the different shapes of receptive field
profiles found in biological vision from a requirement that the visual system
should be invariant to the natural types of image transformations that occur in
its environment.Comment: 40 pages, 17 figure
Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates
The study of cerebral anatomy in developing neonates is of great importance for
the understanding of brain development during the early period of life. This
dissertation therefore focuses on three challenges in the modelling of cerebral
anatomy in neonates during brain development. The methods that have been
developed all use Magnetic Resonance Images (MRI) as source data.
To facilitate study of vascular development in the neonatal period, a set of image
analysis algorithms are developed to automatically extract and model cerebral
vessel trees. The whole process consists of cerebral vessel tracking from
automatically placed seed points, vessel tree generation, and vasculature
registration and matching. These algorithms have been tested on clinical Time-of-
Flight (TOF) MR angiographic datasets.
To facilitate study of the neonatal cortex a complete cerebral cortex segmentation
and reconstruction pipeline has been developed. Segmentation of the neonatal
cortex is not effectively done by existing algorithms designed for the adult brain
because the contrast between grey and white matter is reversed. This causes pixels
containing tissue mixtures to be incorrectly labelled by conventional methods. The
neonatal cortical segmentation method that has been developed is based on a novel
expectation-maximization (EM) method with explicit correction for mislabelled
partial volume voxels. Based on the resulting cortical segmentation, an implicit
surface evolution technique is adopted for the reconstruction of the cortex in
neonates. The performance of the method is investigated by performing a detailed
landmark study.
To facilitate study of cortical development, a cortical surface registration algorithm
for aligning the cortical surface is developed. The method first inflates extracted
cortical surfaces and then performs a non-rigid surface registration using free-form
deformations (FFDs) to remove residual alignment. Validation experiments using
data labelled by an expert observer demonstrate that the method can capture local
changes and follow the growth of specific sulcus
Idealized computational models for auditory receptive fields
This paper presents a theory by which idealized models of auditory receptive
fields can be derived in a principled axiomatic manner, from a set of
structural properties to enable invariance of receptive field responses under
natural sound transformations and ensure internal consistency between
spectro-temporal receptive fields at different temporal and spectral scales.
For defining a time-frequency transformation of a purely temporal sound
signal, it is shown that the framework allows for a new way of deriving the
Gabor and Gammatone filters as well as a novel family of generalized Gammatone
filters, with additional degrees of freedom to obtain different trade-offs
between the spectral selectivity and the temporal delay of time-causal temporal
window functions.
When applied to the definition of a second-layer of receptive fields from a
spectrogram, it is shown that the framework leads to two canonical families of
spectro-temporal receptive fields, in terms of spectro-temporal derivatives of
either spectro-temporal Gaussian kernels for non-causal time or the combination
of a time-causal generalized Gammatone filter over the temporal domain and a
Gaussian filter over the logspectral domain. For each filter family, the
spectro-temporal receptive fields can be either separable over the
time-frequency domain or be adapted to local glissando transformations that
represent variations in logarithmic frequencies over time. Within each domain
of either non-causal or time-causal time, these receptive field families are
derived by uniqueness from the assumptions.
It is demonstrated how the presented framework allows for computation of
basic auditory features for audio processing and that it leads to predictions
about auditory receptive fields with good qualitative similarity to biological
receptive fields measured in the inferior colliculus (ICC) and primary auditory
cortex (A1) of mammals.Comment: 55 pages, 22 figures, 3 table
Techniques for Realtime Viewing and Manipulation of Volumetric Data
Visualizing and manipulating volumetric data is a major component in many areas including anatomical registration in biomedical fields, seismic data analysis in the oil industry, machine part design in computer-aided geometric design, character animation in the movie industry, and fluid simulation. These industries have to meet the demands of the times and be able to make meaningful assertions about the data they generate. The shear size of this data presents many challenges to facilitating realtime interaction. In the recent decade, graphics hardware has become increasingly powerful and more sophisticated which has introduced a new realm of possibilities for processing volumetric data. This thesis focuses on a suite of techniques for viewing and editing volumetric data that efficiently use the processing power of central processing units (CPUs) as well as the large processing power of the graphics hardware (GPUs). This work begins with an algorithm to improve the efficiency of a texture-based volume rendering. We continue with a framework for performing realtime constructive solid geometry (CSG) with complex shapes and smoothing operations on watertight meshes based on a variation of Depth Peeling. We then move to an intuitive technique for deforming volumetric data using a collection of control points. Finally, we apply this technique to image registration of 3-dimensional computed tomography (CT) images used for lung cancel treatment, planning
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