Developing the Quantitative Histopathology Image Ontology : A case study using the hot spot detection problem

Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data. To foster organized, cross-disciplinary, information-driven collaborations in the pathological imaging field, we propose to develop an ontology to represent imaging data and methods used in pathological imaging and analysis, and call it Quantitative Histopathological Imaging Ontology – QHIO. We apply QHIO to breast cancer hot-spot detection with the goal of enhancing reliability of detection by promoting the sharing of data between image analysts

The capabilities approach: fostering contexts for enhancing mental health and wellbeing across the globe

Concerted efforts have been made in recent years to achieve equity and equality in mental health for all people across the globe. This has led to the emergence of Global Mental Health as an area of study and practice. The momentum that this has created has contributed to the development, implementation and evaluation of services for priority mental disorders in many low- and middle-income countries. This paper discusses two related issues that may be serving to limit the success of mental health initiatives across the globe, and proposes potential solutions to these issues. First, there has been a lack of sophistication in determining what constitutes a ‘good outcome’ for people experiencing mental health difficulties. Even though health is defined and understood as a state of ‘wellbeing’ and not merely an absence of illness, mental health interventions tend to narrowly focus on reducing symptoms of mental illness. The need to also focus more broadly on enhancing subjective wellbeing is highlighted. The second limitation relates to the lack of an overarching theoretical framework guiding efforts to reduce inequalities and inequities in mental health across the globe. This paper discusses the potential impact that the Capabilities Approach (CA) could have for addressing both of these issues. As a framework for human development, the CA places emphasis on promoting wellbeing through enabling people to realise their capabilities and engage in behaviours that they subjectively value. The utilization of the CA to guide the development and implementation of mental health interventions can help Global Mental Health initiatives to identify sources of social inequality and structural violence that may impede freedom and individuals’ opportunities to realise their capabilities

Horizons and Perspectives eHealth

EHealth platform represents the combined use of IT technologies and electronic communications in the health field, using data (electronically transmitted, stored and accessed) with a clinical, educational and administrative purpose, both locally and distantly. eHealth has the significant capability to increase the movement in the direction of services centered towards citizens, improving the quality of the medical act, integrating the application of Medical Informatics (Medical IT), Telemedicine, Health Telematics, Telehealth, Biomedical engineering and Bioinformatics. Supporting the creation, development and recognition of a specific eHealth zone, the European Union policies develop through its programs FP6 and FP7, European-scale projects in the medical information technologies (the electronic health cards, online medical care, medical web portals, trans-European nets for medical information, biotechnology, generic instruments and medical technologies for health, ICT mobile systems for remote monitoring). The medical applications like electronic health cards ePrescription, eServices, medical eLearning, eSupervision, eAdministration are integral part of what is the new medical branch-eHealth, being in a continuous expansion due to the support from the global political, financial and medical organizations; the degree of implementation of the eHealth platform varying according to the development level of the communication infrastructure, allocated funds, intensive political priorities and governmental organizations opened to the new IT challenges.eHealth, telemedicine, telehealth, bioinformatics, telematics

Beyond Disability Civil Rights

[Excerpt] This Article argues that to be effective, both domestic and international disability rights must adopt a disability human rights paradigm. Such a framework combines the type of civil and political rights provided by antidiscrimination legislation (also called negative or first-generation rights) with the full spectrum of social, cultural, and economic measures (also called positive or second-generation rights) bestowed by many human rights treaties.16 By acting holistically, this agenda accounts for factors normally exogenous to civil rights laws and ensures that individuals can flourish and participate in their societies. Accordingly, our intention is to share some thoughts on how to best provide disabled citizens with equal opportunity rather than “merely” equal treatment. Internationally, States and civil society organizations have been developing innovative and effective equality measures. We draw on their experiences in providing examples of how disability legislation and policy can be developed to implement a more holistic human rights approach. These lessons are also pertinent for invigorating the ADA

HIV testing intervention development among men who have sex with men in the developed world

HIV testing is a ‘gateway’ technology, enabling access to treatment and HIV prevention. Biomedical approaches to prevention, such as pre-exposure prophylaxis and treatment as prevention, require accurate and regular HIV test results. HIV testing also represents a powerful ‘teachable moment’ for behavioural prevention. An increasing range of HIV tests and the emergence of self-managed diagnostic technologies (e.g. self-testing) means there is now considerable diversification of when, where and how results are available to those who test. These changes have profound implications for intervention development and, indeed, health service redesign. This paper highlights the need for better ways of conceptualising testing in order to capitalise on the health benefits that diverse HIV testing interventions will bring. A multidimensional framework is proposed to capture ongoing developments in HIV testing among men who have sex with men and focus on the intersection of: (1) the growing variety of HIV testing technologies and the associated diversification of their pathways into care; (2) psychosocial insights into the behavioural domain of HIV testing; and (3) better appreciation of population factors associated with heterogeneity and concomitant inequities. By considering these three aspects of HIV testing in parallel, it is possible to identify gaps, limitations and opportunities in future HIV testing-related interventions. Moreover, it is possible to explore and map how diverse interventions may work together having additive effects. Only a holistic and dynamic framework that captures the increasing complexity of HIV testing is fit for purpose to deliver the maximum public health benefit of HIV testing

Selecting Web Services with Security Compliances: A Managerial Perspective

This paper proposes a framework of a decision support system (DSS) for the assessment process of selecting Web services with security compliances consistent with the enterprise business goal. The proposed DSS framework is a systematic assessment model which could aid IS managers in making decision on which Web services would most likely meet the security requirements of their information systems. The proposed process is based on the standard ISO/IEC 15408, the Common Criteria for Information Technology Security Evaluation. The framework consists of five components: (i) Identification of security objectives; (ii) Formulation of criteria; (iii) Selection of candidate Web services; (iv) Security profiling of Web services; and (v) Variance analysis engine. The framework is presented with a running example to demonstrate the applicability of the approach

Online gambling and crime: a sure bet?

Despite a growing body of research that is exploring the deleterious social effects of online gambling, there has, to date, been very little empirical research into internet gambling and crime. This paper seeks to initiate discussion and exploration of the dimensions of crime in and around internet gambling sites through an analysis of the current literature on gambling online. The paper forms part of a wider study that seeks to examine online gambling related crime and identify appropriate legal, technological and educational frameworks through which to limit victimisation

Employing Emotion Cues to Verify Speakers in Emotional Talking Environments

Usually, people talk neutrally in environments where there are no abnormal talking conditions such as stress and emotion. Other emotional conditions that might affect people talking tone like happiness, anger, and sadness. Such emotions are directly affected by the patient health status. In neutral talking environments, speakers can be easily verified, however, in emotional talking environments, speakers cannot be easily verified as in neutral talking ones. Consequently, speaker verification systems do not perform well in emotional talking environments as they do in neutral talking environments. In this work, a two-stage approach has been employed and evaluated to improve speaker verification performance in emotional talking environments. This approach employs speaker emotion cues (text-independent and emotion-dependent speaker verification problem) based on both Hidden Markov Models (HMMs) and Suprasegmental Hidden Markov Models (SPHMMs) as classifiers. The approach is comprised of two cascaded stages that combines and integrates emotion recognizer and speaker recognizer into one recognizer. The architecture has been tested on two different and separate emotional speech databases: our collected database and Emotional Prosody Speech and Transcripts database. The results of this work show that the proposed approach gives promising results with a significant improvement over previous studies and other approaches such as emotion-independent speaker verification approach and emotion-dependent speaker verification approach based completely on HMMs.Comment: Journal of Intelligent Systems, Special Issue on Intelligent Healthcare Systems, De Gruyter, 201