ANN for Parkinson’s Disease Prediction

Parkinson's Disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Doctors do not know what causes it and finds difficulty in early diagnosing the presence of Parkinson’s disease. An artificial neural network system with back propagation algorithm is presented in this paper for helping doctors in identifying PD. Previous research with regards to predict the presence of the PD has shown accuracy rates up to 93% [1]; however, accuracy of prediction for small classes is reduced. The proposed design of the neural network system causes a significant increase of robustness. It is also has shown that networks recognition rates reached 100%

PhoneMD: Learning to Diagnose Parkinson's Disease from Smartphone Data

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However, misdiagnoses are common. One factor that contributes to misdiagnoses is that the symptoms of Parkinson's disease may not be prominent at the time the clinical assessment is performed. Here, we present a machine-learning approach towards distinguishing between people with and without Parkinson's disease using long-term data from smartphone-based walking, voice, tapping and memory tests. We demonstrate that our attentive deep-learning models achieve significant improvements in predictive performance over strong baselines (area under the receiver operating characteristic curve = 0.85) in data from a cohort of 1853 participants. We also show that our models identify meaningful features in the input data. Our results confirm that smartphone data collected over extended periods of time could in the future potentially be used as a digital biomarker for the diagnosis of Parkinson's disease.Comment: AAAI Conference on Artificial Intelligence 201

The Impact of Emotion Focused Features on SVM and MLR Models for Depression Detection

Major depressive disorder (MDD) is a common mental health diagnosis with estimates upwards of 25% of the United States population remain undiagnosed. Psychomotor symptoms of MDD impacts speed of control of the vocal tract, glottal source features and the rhythm of speech. Speech enables people to perceive the emotion of the speaker and MDD decreases the mood magnitudes expressed by an individual. This study asks the questions: “if high level features deigned to combine acoustic features related to emotion detection are added to glottal source features and mean response time in support vector machines and multivariate logistic regression models, would that improve the recall of the MDD class?” To answer this question, a literature review goes through common features in MDD detection, especially features related to emotion recognition. Using feature transformation, emotion recognition composite features are produced and added to glottal source features for model evaluation

Gaining Computational Insight into Psychological Data: Applications of Machine Learning with Eating Disorders and Autism Spectrum Disorder

Over the past 100 years, assessment tools have been developed that allow us to explore mental and behavioral processes that could not be measured before. However, conventional statistical models used for psychological data are lacking in thoroughness and predictability. This provides a perfect opportunity to use machine learning to study the data in a novel way. In this paper, we present examples of using machine learning techniques with data in three areas: eating disorders, body satisfaction, and Autism Spectrum Disorder (ASD). We explore clustering algorithms as well as virtual reality (VR). Our first study employs the k-means clustering algorithm to explore eating disorder behaviors. Our results show that the Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA) are good predictors of eating disorder behavior. Our second study uses a hierarchical clustering algorithm to find patterns in the dataset that were previously not considered. We found four clusters that may highlight the unique differences between participants who had positive body image versus participants who had negative body image. The final chapter presents a case study with a specific VR tool, Bob’s Fish Shop, and users with ASD and Attention Deficit Hyperactivity Disorder (ADHD). We hypothesize that, through the repetition and analysis of these virtual interactions, users can improve social and conversational understanding. Through the implementation of various machine learning algorithms and programs, we can study the human experience in a way that has never been done. We can account for neurodiverse populations and assist them in ways that are not only helpful but also educational

A Voice-Based Automated System for PTSD Screening and Monitoring

Comprehensive evaluation of PTSD includes diagnostic interviews, self-report testing, and physiological reactivity measures. It is often difficult and costly to diagnose PTSD due to patient access and the variability in symptoms presented. Additionally, potential patients are often reluctant to seek help due to the stigma associated with the disorder. A voice-based automated system that is able to remotely screen individuals at high risk for PTSD and monitor their symptoms during treatment has the potential to make great strides in alleviating the barriers to cost effective PTSD assessment and progress monitoring. In this paper we present a voice-based automated Tele-PTSD Monitor (TPM) system currently in development, designed to remotely screen, and provide assistance to clinicians in diagnosing PTSD. The TPM system can be accessed via a Public Switched Telephone Network (PSTN) or the Internet. The acquired voice data is then sent to a secure server to invoke the PTSD Scoring Engine (PTSD-SE) where a PTSD mental health score is computed. If the score exceeds a predefined threshold, the system will notify clinicians (via email or short message service) for confirmation and/or an appropriate follow-up assessment and intervention. The TPM system requires only voice input and performs computer-based automated PTSD scoring, resulting in low cost and easy field-deployment. The concept of the TPM system was supported using a limited dataset with an average detection accuracy of up to 95.88%