Methods, systems, and devices for pairing vagus nerve stimulation with motor therapy in stroke patients

A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.Board of Regents, University of Texas Syste

Methods, systems, and devices for pairing vagus nerve stimulation with motor therapy in stroke patients

A method of treating motor deficits in a stroke patient, comprising assessing a patient's motor deficits, determining therapeutic goals for the patient, based on the patient's motor deficits, selecting therapeutic tasks based on the therapeutic goals, performing each of the selected therapeutic tasks repetitively, observing the performance of the therapeutic tasks, initiating the stimulation of the vagus nerve manually at approximately a predetermined moment during the performance of the therapeutic tasks, stimulating the vagus nerve of the patient during the performance of the selected therapeutic tasks, and improving the patient's motor deficits.Board of Regents, University of Texas Syste

Chronic Use of a Sensitized Bionic Hand Does Not Remap the Sense of Touch

Electrical stimulation of tactile nerve fibers can be used to restore touch through a bionic hand. Ortiz-Catalan et al. show that a mismatch between the location of the sensor on the bionic hand and the tactile experience is not resolved after long-term prosthesis use

Creation of spin-triplet Cooper pairs in the absence of magnetic ordering

In superconducting spintronics, it is essential to generate spin-triplet Cooper pairs on demand. Up to now, proposals to do so concentrate on hybrid structures in which a superconductor (SC) is combined with a magnetically ordered material (or an external magnetic field). We, instead, identify a novel way to create and isolate spin-triplet Cooper pairs in the absence of any magnetic ordering. This achievement is only possible because we drive a system with strong spin-orbit interaction--the Dirac surface states of a strong topological insulator (TI)--out of equilibrium. In particular, we consider a bipolar TI-SC-TI junction, where the electrochemical potentials in the outer leads differ in their overall sign. As a result, we find that nonlocal singlet pairing across the junction is completely suppressed for any excitation energy. Hence, this junction acts as a perfect spin triplet filter across the SC generating equal-spin Cooper pairs via crossed Andreev reflection.Comment: 12 pages, 8 figure

Yu-Shiba-Rusinov states in phase-biased S-QD-S junctions

We study the effects of a phase difference on Yu-Shiba-Rusinov (YSR) states in a spinful Coulomb-blockaded quantum dot contacted by a superconducting loop. In the limit where charging energy is larger than the superconducting gap, we determine the subgap excitation spectrum, the corresponding supercurrent, and the differential conductance as measured by a normal-metal tunnel probe. In absence of a phase difference only one linear combination of the superconductor lead electrons couples to the spin, which gives a single YSR state. With finite phase difference, however, it is effectively a two-channel scattering problem and therefore an additional state emerges from the gap edge. The energy of the phase-dependent YSR states depend on the gate voltage and one state can cross zero energy twice inside the valley with odd occupancy. These crossings are shifted by the phase difference towards the charge degeneracy points, corresponding to larger exchange couplings. Moreover, the zero-energy crossings give rise to resonant peaks in the differential conductance with magnitude $4e^2/h$. Finally, we demonstrate that the quantum fluctuations of the dot spin do not alter qualitatively any of the results.Comment: 13 pages, 7 figure