6,948 research outputs found
Automated testsystem of COGNISION headset for cognitive diagnosis.
There are more than 15 million Americans suffering from a chronic cognitive disability in the Unites States. Researchers have been exploring many different quantitative measures, such as event related potentials (ERP), electro-encephalogram (EEG), Magnetic Encephalogram (MEG) and Brain volumetry to accurately and repeatedly diagnose patients suffering from debilitating cognitive disorders. More than a million cases have been diagnosed every year, with many of those patients being misdiagnosed as a result of inadequate diagnostic and quality control tools. As a result, the medical device industry has been actively developing alternative diagnostic techniques, which implement one or more quantitative measures to improve diagnosis. For example, Neuronetrix (Louisville, KY) developed COGNISION™ that utilizes both ERP and EEG data to diagnose the cognitive ability of patients. The system has shown to be a powerful tool; however, its commercial success would be limited without lack of a fast and effective method of testing and validating the product. Thus, the goal of this study is to develop, test and validate a new “Testset” system for accurately and repeatedly validating the COGNISION™ Headset. A Testset was constructed that is comprised of a software control component designed using the Labview G programming language, which runs on a computer terminal, a Data Acquisition (DAQ) card and switching board. The Testset is connected to a series of testing fixtures for interfacing with the various components of the Headset. The Testset evaluates the Headset at multiple stages of the manufacturing process as a whole system or by its individual components. At the first stage of production the Electrode Strings, amplifier board (Uberyoke), and Headset Control Unit (HCU) are tested and operated as individual printed circuit boards (PCBs). These components are again tested as mid-level assemblies and/or at the finished product stage as a complete autonomous system with the Testset monitoring the process. All tests are automated, requiring only a few parameters to be defined before a test is initiated by a single button press, and then selected test sequences are begun for that particular component or system and are completed in a few minutes. A total of 2 Testsets were constructed and used to validate 10 Headsets. An automated software system was designed to control the Testset. The Testset demonstrated the ability to validate and test 100% of the individual components and completed assembled Headsets. The Testsets were found to be within 5% of the manufacturing specifications. Subsequently, the Automated Testset developed in this study enabled the manufacturer to provide a comprehensive report on the calibration parameters of the Headset, which is retained on file for each unit sold. The automated testsystem’s statistical analysis shows that the two Testsets yielded reliable and consistent results with each other
Earth benefits from NASA research and technology. Life sciences applications
This document provides a representative sampling of examples of Earth benefits in life-sciences-related applications, primarily in the area of medicine and health care, but also in agricultural productivity, environmental monitoring and safety, and the environment. This brochure is not intended as an exhaustive listing, but as an overview to acquaint the reader with the breadth of areas in which the space life sciences have, in one way or another, contributed a unique perspective to the solution of problems on Earth. Most of the examples cited were derived directly from space life sciences research and technology. Some examples resulted from other space technologies, but have found important life sciences applications on Earth. And, finally, we have included several areas in which Earth benefits are anticipated from biomedical and biological research conducted in support of future human exploration missions
Southwest Research Institute assistance to NASA in biomedical areas of the technology utilization program Final report, 1 Feb. 1969 - 24 Aug. 1970
Research progress in technology transfer by NASA Biomedical Application Tea
Technology applications
A summary of NASA Technology Utilization programs for the period of 1 December 1971 through 31 May 1972 is presented. An abbreviated description of the overall Technology Utilization Applications Program is provided as a background for the specific applications examples. Subjects discussed are in the broad headings of: (1) cancer, (2) cardiovascular disease, (2) medical instrumentation, (4) urinary system disorders, (5) rehabilitation medicine, (6) air and water pollution, (7) housing and urban construction, (8) fire safety, (9) law enforcement and criminalistics, (10) transportation, and (11) mine safety
Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia
Cognitive function is an important end point of treatments in dementia clinical trials. Measuring cognitive function by standardized tests, however, is biased toward highly constrained environments (such as hospitals) in selected samples. Patient-powered real-world evidence using information and communication technology devices, including environmental and wearable sensors, may help to overcome these limitations. This position paper describes current and novel information and communication technology devices and algorithms to monitor behavior and function in people with prodromal and manifest stages of dementia continuously, and discusses clinical, technological, ethical, regulatory, and user-centered requirements for collecting real-world evidence in future randomized controlled trials. Challenges of data safety, quality, and privacy and regulatory requirements need to be addressed by future smart sensor technologies. When these requirements are satisfied, these technologies will provide access to truly user relevant outcomes and broader cohorts of participants than currently sampled in clinical trials
Fog Computing in Medical Internet-of-Things: Architecture, Implementation, and Applications
In the era when the market segment of Internet of Things (IoT) tops the chart
in various business reports, it is apparently envisioned that the field of
medicine expects to gain a large benefit from the explosion of wearables and
internet-connected sensors that surround us to acquire and communicate
unprecedented data on symptoms, medication, food intake, and daily-life
activities impacting one's health and wellness. However, IoT-driven healthcare
would have to overcome many barriers, such as: 1) There is an increasing demand
for data storage on cloud servers where the analysis of the medical big data
becomes increasingly complex, 2) The data, when communicated, are vulnerable to
security and privacy issues, 3) The communication of the continuously collected
data is not only costly but also energy hungry, 4) Operating and maintaining
the sensors directly from the cloud servers are non-trial tasks. This book
chapter defined Fog Computing in the context of medical IoT. Conceptually, Fog
Computing is a service-oriented intermediate layer in IoT, providing the
interfaces between the sensors and cloud servers for facilitating connectivity,
data transfer, and queryable local database. The centerpiece of Fog computing
is a low-power, intelligent, wireless, embedded computing node that carries out
signal conditioning and data analytics on raw data collected from wearables or
other medical sensors and offers efficient means to serve telehealth
interventions. We implemented and tested an fog computing system using the
Intel Edison and Raspberry Pi that allows acquisition, computing, storage and
communication of the various medical data such as pathological speech data of
individuals with speech disorders, Phonocardiogram (PCG) signal for heart rate
estimation, and Electrocardiogram (ECG)-based Q, R, S detection.Comment: 29 pages, 30 figures, 5 tables. Keywords: Big Data, Body Area
Network, Body Sensor Network, Edge Computing, Fog Computing, Medical
Cyberphysical Systems, Medical Internet-of-Things, Telecare, Tele-treatment,
Wearable Devices, Chapter in Handbook of Large-Scale Distributed Computing in
Smart Healthcare (2017), Springe
Automatic autism spectrum disorder detection using artificial intelligence methods with MRI neuroimaging: A review
Autism spectrum disorder (ASD) is a brain condition characterized by
diverse signs and symptoms that appear in early childhood. ASD is also
associated with communication deficits and repetitive behavior in affected
individuals. Various ASD detection methods have been developed, including
neuroimaging modalities and psychological tests. Among these methods,
magnetic resonance imaging (MRI) imaging modalities are of paramount
importance to physicians. Clinicians rely on MRI modalities to diagnose
ASD accurately. The MRI modalities are non-invasive methods that include
functional (fMRI) and structural (sMRI) neuroimaging methods. However,
diagnosing ASD with fMRI and sMRI for specialists is often laborious and
time-consuming; therefore, several computer-aided design systems (CADS)
based on artificial intelligence (AI) have been developed to assist specialist
physicians. Conventional machine learning (ML) and deep learning (DL) are
the most popular schemes of AI used for diagnosing ASD. This study aims to
review the automated detection of ASD using AI. We review several CADS that
have been developed using ML techniques for the automated diagnosis of
ASD using MRI modalities. There has been very limited work on the use of DL techniques to develop automated diagnostic models for ASD. A summary of
the studies developed using DL is provided in the Supplementary Appendix.
Then, the challenges encountered during the automated diagnosis of ASD
using MRI and AI techniques are described in detail. Additionally, a graphical
comparison of studies using ML and DL to diagnose ASD automatically
is discussed. We suggest future approaches to detecting ASDs using AI
techniques and MRI neuroimaging.Qatar National
Librar
Automatic Autism Spectrum Disorder Detection Using Artificial Intelligence Methods with MRI Neuroimaging: A Review
Autism spectrum disorder (ASD) is a brain condition characterized by diverse
signs and symptoms that appear in early childhood. ASD is also associated with
communication deficits and repetitive behavior in affected individuals. Various
ASD detection methods have been developed, including neuroimaging modalities
and psychological tests. Among these methods, magnetic resonance imaging (MRI)
imaging modalities are of paramount importance to physicians. Clinicians rely
on MRI modalities to diagnose ASD accurately. The MRI modalities are
non-invasive methods that include functional (fMRI) and structural (sMRI)
neuroimaging methods. However, the process of diagnosing ASD with fMRI and sMRI
for specialists is often laborious and time-consuming; therefore, several
computer-aided design systems (CADS) based on artificial intelligence (AI) have
been developed to assist the specialist physicians. Conventional machine
learning (ML) and deep learning (DL) are the most popular schemes of AI used
for diagnosing ASD. This study aims to review the automated detection of ASD
using AI. We review several CADS that have been developed using ML techniques
for the automated diagnosis of ASD using MRI modalities. There has been very
limited work on the use of DL techniques to develop automated diagnostic models
for ASD. A summary of the studies developed using DL is provided in the
appendix. Then, the challenges encountered during the automated diagnosis of
ASD using MRI and AI techniques are described in detail. Additionally, a
graphical comparison of studies using ML and DL to diagnose ASD automatically
is discussed. We conclude by suggesting future approaches to detecting ASDs
using AI techniques and MRI neuroimaging
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