15,252 research outputs found

    The 'At-risk mental state' for psychosis in adolescents : clinical presentation, transition and remission.

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    Despite increased efforts over the last decade to prospectively identify individuals at ultra-high risk of developing a psychotic illness, limited attention has been specifically directed towards adolescent populations (<18 years). In order to evaluate how those under 18 fulfilling the operationalised criteria for an At-Risk Mental State (ARMS) present and fare over time, we conducted an observational study. Participants (N = 30) generally reported a high degree of functional disability and frequent and distressing perceptual disturbance, mainly in the form of auditory hallucinations. Seventy percent (21/30) were found to fulfil the criteria for a co-morbid ICD-10 listed mental health disorder, with mood (affective; 13/30) disorders being most prevalent. Overall transition rates to psychosis were low at 24 months follow-up (2/28; 7.1 %) whilst many participants demonstrated a significant reduction in psychotic-like symptoms. The generalisation of these findings may be limited due to the small sample size and require replication in a larger sample

    Dissociation and interpersonal autonomic physiology in psychotherapy research: an integrative view encompassing psychodynamic and neuroscience theoretical frameworks

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    Interpersonal autonomic physiology is an interdisciplinary research field, assessing the relational interdependence of two (or more) interacting individual both at the behavioral and psychophysiological levels. Despite its quite long tradition, only eight studies since 1955 have focused on the interaction of psychotherapy dyads, and none of them have focused on the shared processual level, assessing dynamic phenomena such as dissociation. We longitudinally observed two brief psychodynamic psychotherapies, entirely audio and video-recorded (16 sessions, weekly frequency, 45 min.). Autonomic nervous system measures were continuously collected during each session. Personality, empathy, dissociative features and clinical progress measures were collected prior and post therapy, and after each clinical session. Two-independent judges, trained psychotherapist, codified the interactions\u2019 micro-processes. Time-series based analyses were performed to assess interpersonal synchronization and de-synchronization in patient\u2019s and therapist\u2019s physiological activity. Psychophysiological synchrony revealed a clear association with empathic attunement, while desynchronization phases (range of length 30-150 sec.) showed a linkage with dissociative processes, usually associated to the patient\u2019s narrative core relational trauma. Our findings are discussed under the perspective of psychodynamic models of Stern (\u201cpresent moment\u201d), Sander, Beebe and Lachmann (dyad system model of interaction), Lanius (Trauma model), and the neuroscientific frameworks proposed by Thayer (neurovisceral integration model), and Porges (polyvagal theory). The collected data allows to attempt an integration of these theoretical approaches under the light of Complex Dynamic Systems. The rich theoretical work and the encouraging clinical results might represents a new fascinating frontier of research in psychotherapy

    The Double-edged Sword: A Mixed Methods Study of the Interplay between Bipolar Disorder and Technology Use

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    Human behavior is increasingly reflected or acted out through technology. This is of particular salience when it comes to changes in behavior associated with serious mental illnesses including schizophrenia and bipolar disorder. Early detection is crucial for these conditions but presently very challenging to achieve. Potentially, characteristics of these conditions\u27 traits and symptoms, at both idiosyncratic and collective levels, may be detectable through technology use patterns. In bipolar disorder specifically, initial evidence associates changes in mood with changes in technology-mediated communication patterns. However much less is known about how people with bipolar disorder use technology more generally in their lives, how they view their technology use in relation to their illness, and, perhaps most crucially, the causal relationship (if any exists) between their technology use and their disease. To address these uncertainties, we conducted a survey of people with bipolar disorder (N = 84). Our results indicate that technology use varies markedly with changes in mood and that technology use broadly may have potential as an early warning signal of mood episodes. We also find that technology for many of these participants is a double-edged sword: acting as both a culprit that can trigger or exacerbate symptoms as well as a support mechanism for recovery. These findings have implications for the design of both early warning systems and technology-mediated interventions

    Attention bias as a mediator of the association between interparental conflict and cortisol reactivity

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    2021 Spring.Includes bibliographical references.The current study aimed to explore whether attention bias mediated the relationship between adolescents' appraisals of interparental conflict (IPC) and cortisol reactivity (CR). There is a robust literature on the relationship between attention bias and anxiety in children and adults (Bar-Haim et al., 2007; Cisler & Koster, 2011), and an emerging literature on how interparental conflict is associated with an attention bias toward angry interactions (Lucas-Thompson et al., 2020). While there is a robust association in the literature between interparental conflict and cortisol reactivity (Davies et al., 2007; Lucas-Thompson, 2012; Koss et al., 2012), the results of this study found no association between the two variables. Similarly, the results of this study indicated no associations between attention bias and any other variables. The results of this study suggest that attention bias may be a moderator, or risk factor in the relationship between IPC and CR. Additionally, further research is needed to determine whether a conflict specific stressor should be used to elicit more variability in cortisol reactivity. Further research should continue to aim to link neurobiological processes to clinically relevant topics, as it is essential to bridge the gap between the medical field and the psychotherapy process

    Early Child Development in Social Context: A Chartbook

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    Reviews more than 30 key indicators of health and development for children up to age 6, as well as social factors in families and communities that affect these outcomes. Offers practical suggestions for health practitioners and parents
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