4,634 research outputs found
Advancing Dynamic Fault Tree Analysis
This paper presents a new state space generation approach for dynamic fault
trees (DFTs) together with a technique to synthesise failures rates in DFTs.
Our state space generation technique aggressively exploits the DFT structure
--- detecting symmetries, spurious non-determinism, and don't cares. Benchmarks
show a gain of more than two orders of magnitude in terms of state space
generation and analysis time. Our approach supports DFTs with symbolic failure
rates and is complemented by parameter synthesis. This enables determining the
maximal tolerable failure rate of a system component while ensuring that the
mean time of failure stays below a threshold
Developing and applying heterogeneous phylogenetic models with XRate
Modeling sequence evolution on phylogenetic trees is a useful technique in
computational biology. Especially powerful are models which take account of the
heterogeneous nature of sequence evolution according to the "grammar" of the
encoded gene features. However, beyond a modest level of model complexity,
manual coding of models becomes prohibitively labor-intensive. We demonstrate,
via a set of case studies, the new built-in model-prototyping capabilities of
XRate (macros and Scheme extensions). These features allow rapid implementation
of phylogenetic models which would have previously been far more
labor-intensive. XRate's new capabilities for lineage-specific models,
ancestral sequence reconstruction, and improved annotation output are also
discussed. XRate's flexible model-specification capabilities and computational
efficiency make it well-suited to developing and prototyping phylogenetic
grammar models. XRate is available as part of the DART software package:
http://biowiki.org/DART .Comment: 34 pages, 3 figures, glossary of XRate model terminolog
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