Deep Retinal Optical Flow: From Synthetic Dataset Generation to Framework Creation and Evaluation

Sustained delivery of regenerative retinal therapies by robotic systems requires intra-operative tracking of the retinal fundus. This thesis presents a supervised convolutional neural network to densely predict optical flow of the retinal fundus, using semantic segmentation as an auxiliary task. Retinal flow information missing due to occlusion by surgical tools or other effects is implicitly inpainted, allowing for the robust tracking of surgical targets. As manual annotation of optical flow is infeasible, a flexible algorithm for the generation of large synthetic training datasets on the basis of given intra-operative retinal images and tool templates is developed. The compositing of synthetic images is approached as a layer-wise operation implementing a number of transforms at every level which can be extended as required, mimicking the various phenomena visible in real data. Optical flow ground truth is calculated from motion transforms with the help of oflib, an open-source optical flow library available from the Python Package Index. It enables the user to manipulate, evaluate, and combine flow fields. The PyTorch version of oflib is fully differentiable and therefore suitable for use in deep learning methods requiring back-propagation. The optical flow estimation from the network trained on synthetic data is evaluated using three performance metrics obtained from tracking a grid and sparsely annotated ground truth points. The evaluation benchmark consists of a series of challenging real intra-operative clips obtained from an extensive internally acquired dataset encompassing representative surgical cases. The deep learning approach clearly outperforms variational baseline methods and is shown to generalise well to real data showing scenarios routinely observed during vitreoretinal procedures. This indicates complex synthetic training datasets can be used to specifically guide optical flow estimation, laying the foundation for a robust system which can assist with intra-operative tracking of moving surgical targets even when occluded

Vision Science and Technology at NASA: Results of a Workshop

A broad review is given of vision science and technology within NASA. The subject is defined and its applications in both NASA and the nation at large are noted. A survey of current NASA efforts is given, noting strengths and weaknesses of the NASA program