Enhancing pharmaceutical packaging through a technology ecosystem to facilitate the reuse of medicines and reduce medicinal waste

The idea of reusing dispensed medicines is appealing to the general public provided its benefits are illustrated, its risks minimized, and the logistics resolved. For example, medicine reuse could help reduce medicinal waste, protect the environment and improve public health. However, the associated technologies and legislation facilitating medicine reuse are generally not available. The availability of suitable technologies could arguably help shape stakeholders’ beliefs and in turn, uptake of a future medicine reuse scheme by tackling the risks and facilitating the practicalities. A literature survey is undertaken to lay down the groundwork for implementing technologies on and around pharmaceutical packaging in order to meet stakeholders’ previously expressed misgivings about medicine reuse (’stakeholder requirements’), and propose a novel ecosystem for, in effect, reusing returned medicines. Methods: A structured literature search examining the application of existing technologies on pharmaceutical packaging to enable medicine reuse was conducted and presented as a narrative review. Results: Reviewed technologies are classified according to different stakeholders’ requirements, and a novel ecosystem from a technology perspective is suggested as a solution to reusing medicines. Conclusion: Active sensing technologies applying to pharmaceutical packaging using printed electronics enlist medicines to be part of the Internet of Things network. Validating the quality and safety of returned medicines through this network seems to be the most effective way for reusing medicines and the correct application of technologies may be the key enabler

How 5G wireless (and concomitant technologies) will revolutionize healthcare?

The need to have equitable access to quality healthcare is enshrined in the United Nations (UN) Sustainable Development Goals (SDGs), which defines the developmental agenda of the UN for the next 15 years. In particular, the third SDG focuses on the need to “ensure healthy lives and promote well-being for all at all ages”. In this paper, we build the case that 5G wireless technology, along with concomitant emerging technologies (such as IoT, big data, artificial intelligence and machine learning), will transform global healthcare systems in the near future. Our optimism around 5G-enabled healthcare stems from a confluence of significant technical pushes that are already at play: apart from the availability of high-throughput low-latency wireless connectivity, other significant factors include the democratization of computing through cloud computing; the democratization of Artificial Intelligence (AI) and cognitive computing (e.g., IBM Watson); and the commoditization of data through crowdsourcing and digital exhaust. These technologies together can finally crack a dysfunctional healthcare system that has largely been impervious to technological innovations. We highlight the persistent deficiencies of the current healthcare system and then demonstrate how the 5G-enabled healthcare revolution can fix these deficiencies. We also highlight open technical research challenges, and potential pitfalls, that may hinder the development of such a 5G-enabled health revolution

EPSRC IMPACT Exhibition

This exhibition was conceived by Dunne (PI) and comprised 16 mixed-media speculative design research projects. It marked the culmination of an EPSRC-funded initiative also partly supported by NESTA. Dunne supervised and then curated the projects by staff, graduates and students of the RCA Design Interactions programme. Each was conducted in collaboration with an external research partner organisation already supported by the EPSRC. The topics covered ranged from renewable energy devices and security technologies to the emerging fields of synthetic biology and quantum computing. Dunne and an advisory panel from EPSRC and NESTA selected themes on the basis of diversity of topic, design opportunities, intellectual and creative challenges, and public relevance. Dunne invited the designers to take a radical, interrogative approach, exploring the social, ethical and political implications of the research. Each designer visited the relevant science lab, consulted with the scientists throughout the project, and participated in a one-day workshop hosted by NESTA between scientists and designers on such forms of collaboration. Designers carried out literature, journal, and project surveys before developing their projects through iterative prototypes. The exhibition, held at the RCA in 2010, was considered by EPSRC to offer a powerful insight into how today’s research might transform our experience of the world. It was reviewed in the Guardian (2010), Wired (2010) and Design Week (2010). Dunne presented ‘IMPACT!’ in conferences including the IDA Congress, ‘Design at the Edges’, Taipei (2011) and at the Wellcome Trust, London (2011). He gave a related lecture to researchers at Microsoft Research Asia, Beijing (2011). Individual exhibits from the project featured in exhibitions: Museum of Modern Art (2011), National Museum of China (2011); Z33 (2010–11); Wellcome Trust (2010–11); Saint-Étienne International Design Biennial (2010); Ars Electronica (2010); The Times Cheltenham Science Festival (2010); and V2_, Institute for the Unstable Media (2010)

Reviewing the Drivers and Challenges in RFID Implementation in the Pharmaceutical Supply Chain

Counterfeiting is a global phenomenon that poses a serious financial threat to the pharmaceutical industry and more importantly jeopardizes public safety and security. Different measures, including new laws and regulations, have been put in place to mitigate the threat and tighten control in the pharmaceuticals supply chain. However, it appears that the most promising countermeasure is track-and-trace technology such as electronic-pedigree (E-pedigree) with Radio Frequency Identification (RFID) technology. In this study we present a framework exploring the antecedents and consequences of RFID applications in the pharmaceutical supply chain. The framework proposes that counterfeiting and E-pedigree regulation will drive the implementation of RFID in the pharmaceutical supply chain, which in turn provides strategic and operational benefits that enable competitive advantage. Meanwhile, the implementation of RFID requires overcoming many operational, technical and financial challenges. The framework provides a springboard that future study can explore using empirical data

IoT-based Asset Management System for Healthcare-related Industries

The healthcare industry has been focusing efforts on optimizing inventory management procedures through the incorporation of Information and Communication Technology, in the form of tracking devices and data mining, to establish ideal inventory models. In this paper, a roadmap is developed towards a technological assessment of the Internet of Things (IoT) in the healthcare industry, 2010–2020. According to the roadmap, an IoT-based healthcare asset management system (IoT-HAMS) is proposed and developed based on Artificial Neural Network (ANN) and Fuzzy Logic (FL), incorporating IoT technologies for asset management to optimize the supply of resources

Enabling medicine reuse using a digital time temperature humidity sensor in an internet of pharmaceutical things concept

Medicinal waste due to improper handling of unwanted medicines creates health and environmental risks. However, the re-dispensing of unused prescribed medicines from patients seems to be accepted by stakeholders when quality and safety requirements are met. Reusing dispensed medicines may help reduce waste, but a comprehensive validation method is not generally available. The design of a novel digital time temperature and humidity indicator based on an Internet of Pharmaceutical Things concept is proposed to facilitate the validation, and a prototype is presented using smart sensors with cloud connectivity acting as the key technology for verifying and enabling the reuse of returned medicines. Deficiency of existing technologies is evaluated based on the results of this development, and recommendations for future research are suggested

Bioinspired Sensor Systems

This editorial summarizes and classifies the contributions presented by different authors to the special issue of the journal Sensors dedicated to Bioinspired Sensor Systems. From the coupling of sensor arrays or networks, plus computer processing abilities, new applications to mimic or to complement human senses are arising in the context of ambient intelligence. Principles used, and illustrative study cases have been presented permitting readers to grasp the current status of the field