718 research outputs found

    Wireless Power and Data Transfer Using Inductively Resonant Coils

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    In electronics, resonance occurs when the admittances of circuit components, the imaginary parts of the component impedances, cancel each other out. Operation of circuits at their resonant frequencies can cause oscillation of signals at extreme levels. Nikola Tesla developed the concept of harnessing the capabilities of resonance by transmitting energy wirelessly between two inductively resonant coils. In 1897, his newly patented design, known as the Tesla coil, was an early prototype used to realize his theory. However, only in relatively recent history has the idea been expanded upon and used for commercial applications. Medical devices, such as pacemakers, are powered through resonant inductive coupling; this form of wireless technology has been in use since the 1960s. Battery-operated toothbrushes are typically charged with one or more small coils in the toothbrush and in the cradle, with power transmitted from the cradle to the toothbrush wirelessly. Newer emerging technology, such as radio-frequency identification (RFID) and near field communication (NFC) has provided end-users with relatively simple products for proximity dependent interaction with their personal devices, such as smartphones. This paper describes the theory and limitations of this emerging technology through the design and construction of a wireless NiCd battery charger, as well as through an investigation of some of the more common protocols for wireless data transmission

    Agglomerative Magnets and Informal Regulatory Networks: Electricity Market Design Convergence in the USA and Continental Europe

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    The absence of one broadly accepted design template for liberalised electricity markets induces regulatory competition and institutional diversity. Focussing on continental Europe and the USA, this analysis explores how agents and structures accelerate or impede the move to one standard market design in the electricity sector. It reveals that market design convergence in Europe is driven by the 'Florence Consensus,' a tripartite coalition between the European Commission fostering European integration and the internal market, informal regulatory networks between grid operators, standardisation authorities and regulators, who have been coordinating their actions in the 'Florence Forum,' and epistemic communities exemplified in the Florence School of Regulation. In contrast, the United States' Federal Energy Regulatory Commission lacks support among politicians, many states' public utility commissions, the neo-liberal intelligentsia and even industrial lobbying groups to effectively push for a standardised market design. However, design convergence in the USA may be induced by the gradual expansion of multi-state markets operated by regional transmission organisations.Electricity, Deregulation, Regulatory Competition, Policy Diffusion

    On the design and implementation of efficient antennas for high frequency-radio frequency identification read/write devices

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    AbstractThis article describes an in‐depth methodical approach to the development of efficient high‐frequency (HF) antennas for use in radio frequency identification (RFID) systems operating at 13.56 MHz. It presents brief theory relevant to RFID communication and sets up a framework within which features and requirements of antennas are linked to key design parameters such as antenna form‐factor and size; RF power level, material and communication protocol. Tuning circuits necessary to adjust the resonance and power matching characteristics of antennas for good transponder interrogation and response recovery are discussed. To validate the approaches outlined, a stepwise design and measurement of an HF antenna for an ISO/IEC 15693 compliant read/write device (RWD) is described. Common practical problems that are often encountered in such design processes are also commented on. The prototyped antenna was tuned, connected to the RWD via a 50 coaxial cable and tested

    Urban Play and the Playable City:A Critical Perspective

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    Characterization of Aggregated Building Heating, Ventilation, and Air Conditioning Load as a Flexibility Service Using Gray‐Box Modeling

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    Integrating large amounts of volatile renewable power into the electricity grid requires ancillary services (ASs) from multiple providers including flexible demand. These should be comparable by uniform and efficiently evaluable performance criteria. The objective is to characterize the technical flexibility of aggregated building heating, ventilation, and air conditioning (HVAC) under different operating conditions. New bounds of flexible power and holding durations, accordingly pay-back power and recovery times, and ramping rates are derived, using a new gray-box model of stochastically actuated aggregations of thermostatically controlled loads (TCLs) that can serve as well for load control. New closed formulas of the expected switching temperatures are derived using survival processes and hazard functions. This ex-ante characterization enables fast decision tools for AS feasibility testing and planning by demand aggregators, as it neither relies on simulation or optimization, nor on the identification and clustering of unit-level parameters. The estimates are explored in a sensitivity study of urban-level heat pump heating with respect to six key input factors. A case study using dynamic regulation signals from Pennsylvania–New Jersey–Maryland (PJM) demonstrates the benefit, in terms of tracking precision, of the refined energy measures over pure energy or power capacity bounds

    Forecasting and Risk Management Techniques for Electricity Markets

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    This book focuses on the recent development of forecasting and risk management techniques for electricity markets. In addition, we discuss research on new trading platforms and environments using blockchain-based peer-to-peer (P2P) markets and computer agents. The book consists of two parts. The first part is entitled “Forecasting and Risk Management Techniques” and contains five chapters related to weather and electricity derivatives, and load and price forecasting for supporting electricity trading. The second part is entitled “Peer-to-Peer (P2P) Electricity Trading System and Strategy” and contains the following five chapters related to the feasibility and enhancement of P2P energy trading from various aspects

    Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass

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    Aims/hypothesis Pancreatic beta cells secrete insulin to maintain glucose homeostasis, and beta cell failure is a hallmark of type 2 diabetes. Glucose triggers insulin secretion in beta cells via oxidative mitochondrial pathways. However, it also feeds mitochondrial anaplerotic pathways, driving citrate export and cytosolic malonyl-CoA production by the acetyl-CoA carboxylase 1 (ACC1) enzyme. This pathway has been proposed as an alternative glucose-sensing mechanism, supported mainly by in vitro data. Here, we sought to address the role of the beta cell ACC1-coupled pathway in insulin secretion and glucose homeostasis in vivo. Methods Acaca, encoding ACC1 (the principal ACC isoform in islets), was deleted in beta cells of mice using the Cre/loxP system. Acaca floxed mice were crossed with Ins2cre mice (ÎČACC1KO; life-long beta cell gene deletion) or Pdx1creER mice (tmx-ÎČACC1KO; inducible gene deletion in adult beta cells). Beta cell function was assessed using in vivo metabolic physiology and ex vivo islet experiments. Beta cell mass was analysed using histological techniques. Results ÎČACC1KO and tmx-ÎČACC1KO mice were glucose intolerant and had defective insulin secretion in vivo. Isolated islet studies identified impaired insulin secretion from beta cells, independent of changes in the abundance of neutral lipids previously implicated as amplification signals. Pancreatic morphometry unexpectedly revealed reduced beta cell size in ÎČACC1KO mice but not in tmx-ÎČACC1KO mice, with decreased levels of proteins involved in the mechanistic target of rapamycin kinase (mTOR)-dependent protein translation pathway underpinning this effect. Conclusions/interpretation Our study demonstrates that the beta cell ACC1-coupled pathway is critical for insulin secretion in vivo and ex vivo and that it is indispensable for glucose homeostasis. We further reveal a role for ACC1 in controlling beta cell growth prior to adulthood

    Crystal Structure of the Receptor-Binding Domain from Newly Emerged Middle East Respiratory Syndrome Coronavirus

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    The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) has infected at least 77 people, with a fatality rate of more than 50%. Alarmingly, the virus demonstrates the capability of human-to-human transmission, raising the possibility of global spread and endangering world health and economy. Here we have identified the receptor-binding domain (RBD) from the MERS-CoV spike protein and determined its crystal structure. This study also presents a structural comparison of MERS-CoV RBD with other coronavirus RBDs, successfully positioning MERS-CoV on the landscape of coronavirus evolution and providing insights into receptor binding by MERS-CoV. Furthermore, we found that MERS-CoV RBD functions as an effective entry inhibitor of MERS-CoV. The identified MERS-CoV RBD may also serve as a potential candidate for MERS-CoV subunit vaccines. Overall, this study enhances our understanding of the evolution of coronavirus RBDs, provides insights into receptor recognition by MERS-CoV, and may help control the transmission of MERS-CoV in humans

    P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation

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    The O-acetylation of polysaccharides is a common modification used by pathogenic organisms to protect against external forces. Pseudomonas aeruginosa secretes the anionic, O-acetylated exopolysaccharide alginate during chronic infection in the lungs of cystic fibrosis patients to form the major constituent of a protective biofilm matrix. Four proteins have been implicated in the O-acetylation of alginate, AlgIJF and AlgX. To probe the biological function of AlgJ, we determined its structure to 1.83 Å resolution. AlgJ is a SGNH hydrolase-like protein, which while structurally similar to the N-terminal domain of AlgX exhibits a distinctly different electrostatic surface potential. Consistent with other SGNH hydrolases, we identified a conserved catalytic triad composed of D190, H192 and S288 and demonstrated that AlgJ exhibits acetylesterase activity in vitro. Residues in the AlgJ signature motifs were found to form an extensive network of interactions that are critical for O-acetylation of alginate in vivo. Using two different electrospray ionization mass spectrometry (ESI-MS) assays we compared the abilities of AlgJ and AlgX to bind and acetylate alginate. Binding studies using defined length polymannuronic acid revealed that AlgJ exhibits either weak or no detectable polymer binding while AlgX binds polymannuronic acid specifically in a length-dependent manner. Additionally, AlgX was capable of utilizing the surrogate acetyl-donor 4-nitrophenyl acetate to catalyze the O-acetylation of polymannuronic acid. Our results, combined with previously published in vivo data, suggest that the annotated O-acetyltransferases AlgJ and AlgX have separate and distinct roles in O-acetylation. Our refined model for alginate acetylation places AlgX as the terminal acetlytransferase and provides a rationale for the variability in the number of proteins required for polysaccharide O-acetylation
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