Dual Output Regulating Rectifier for an Implantable Neural Interface

This paper presents the design of a power management circuit consisting of a dual output regulating rectifier configuration featuring pulse width modulation (PWM) and pulse frequency modulation (PFM) to control the regulated output of 1.8 V, and 3.3 V from a single input ac voltage. The PFM control feedback consists of feedback-driven regulation to adjust the driving frequency of the power transistors through the buffers in the active rectifier. The PWM mode control provides a feedback loop to accurately adjust the conduction duration. The design also includes an adiabatic charge pump (CP) to power stimulators in an implantable neural interface. The adiabatic CP consists of latch up and power saving topologies to enhance its energy efficiency. Simulation results show that the dual regulating rectifier has 94.3% voltage conversion efficiency with an ac input magnitude of 3.5 Vp. The power transfer efficiency of the regulated 3.3 V output voltage is 82.3%. The dual output regulating rectifier topology is suitable for multi-functional implantable devices. The adiabatic CP has an overall efficiency of 92.9% with an overall on-chip capacitance of 60 pF. The circuit was designed in a 180-nm CMOS technology

Efficient Dual Output Regulating Rectifier and Adiabatic Charge Pump for Biomedical Applications Employing Wireless Power Transfer †

A power management unit (PMU) is an essential block for diversified multi-functional low-power Internet of Things (IoT) and biomedical electronics. This paper includes a theoretical analysis of a high current, single-stage ac-dc, reconfigurable, dual output, regulating rectifier consisting of pulse width modulation (PWM) and pulse frequency modulation (PFM). The regulating rectifier provides two independently regulated supply voltages of 1.8 V and 3.3 V from an input ac voltage. The PFM control feedback consists of feedback-driven regulation to adjust the driving frequency of the power transistors through adaptive buffers in the active rectifier. The PWM/PFM mode control provides a feedback loop to adjust the conduction duration accurately and minimize power losses. The design also includes an adiabatic charge pump (CP) to provide a higher voltage level. The adiabatic CP consists of latch-up and power-saving topologies to enhance its power efficiency. Simulation results show that the dual regulating rectifier has 94.3% voltage conversion efficiency with an ac input magnitude of 3.5 Vp. The power conversion efficiency of the regulated 3.3 V output voltage is 82.3%. The adiabatic CP has an overall voltage conversion efficiency (VCE) of 92.9% with a total on-chip capacitance of 60 pF. The circuit was designed using 180 nm CMOS technology

Modelling of Implantable Photovoltaic Cell based on Human Skin Types

Implantable electronic devices are emerging as important healthcare technologies due to their sustainable operation and low risk of infection. To overcome the drawbacks of the built-in battery in implantable devices, energy harvesting from the human body or another external source is required. Energy harvesting using appropriately sized and properly designed photovoltaic cells enable implantable medical devices to be autonomous and self-powered. Among the challenges in using PV cells is the small fraction of incident light that penetrates the skin. Thus, it is necessary to involve such physical properties in the energy harvesting system design. Consequently, we propose a novel photodiode model that considers skin loss in different ethnic groups. Our physical simulations have been implemented using COMSOL and MATLAB. Circuit and system modelling have been performed using Cadence 180nm TSMC technology. Our results show that the transmittance of near infrared light is almost the same in three skin types: Caucasian, Asian and African. Maximum power delivery of 12 μW (African skin) and 14 μW (Caucasian and Asian skin) were achieved at 0.45 V. With the help of a power management unit, an output voltage of 1.8–2 V was achieved using the PV cells

Fully Integrated Biochip Platforms for Advanced Healthcare

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring of several human metabolites can be addressed by using fully integrated and minimally invasive devices located in the sub-cutis, typically in the peritoneal region. This extends the techniques of continuous monitoring of glucose currently being pursued with diabetic patients. However, several issues have to be considered in order to succeed in developing fully integrated and minimally invasive implantable devices. These innovative devices require a high-degree of integration, minimal invasive surgery, long-term biocompatibility, security and privacy in data transmission, high reliability, high reproducibility, high specificity, low detection limit and high sensitivity. Recent advances in the field have already proposed possible solutions for several of these issues. The aim of the present paper is to present a broad spectrum of recent results and to propose future directions of development in order to obtain fully implantable systems for the continuous monitoring of the human metabolism in advanced healthcare applications

e-SAFE: Secure, Efficient and Forensics-Enabled Access to Implantable Medical Devices

To facilitate monitoring and management, modern Implantable Medical Devices (IMDs) are often equipped with wireless capabilities, which raise the risk of malicious access to IMDs. Although schemes are proposed to secure the IMD access, some issues are still open. First, pre-sharing a long-term key between a patient's IMD and a doctor's programmer is vulnerable since once the doctor's programmer is compromised, all of her patients suffer; establishing a temporary key by leveraging proximity gets rid of pre-shared keys, but as the approach lacks real authentication, it can be exploited by nearby adversaries or through man-in-the-middle attacks. Second, while prolonging the lifetime of IMDs is one of the most important design goals, few schemes explore to lower the communication and computation overhead all at once. Finally, how to safely record the commands issued by doctors for the purpose of forensics, which can be the last measure to protect the patients' rights, is commonly omitted in the existing literature. Motivated by these important yet open problems, we propose an innovative scheme e-SAFE, which significantly improves security and safety, reduces the communication overhead and enables IMD-access forensics. We present a novel lightweight compressive sensing based encryption algorithm to encrypt and compress the IMD data simultaneously, reducing the data transmission overhead by over 50% while ensuring high data confidentiality and usability. Furthermore, we provide a suite of protocols regarding device pairing, dual-factor authentication, and accountability-enabled access. The security analysis and performance evaluation show the validity and efficiency of the proposed scheme

Power management using photovoltaic cells for implantable devices

This paper presents a novel inductor-less switched capacitor (SC) DC-DC converter, which generates simultaneous dual-output voltages for implantable electronic devices. Present dual output converters are limited to fixed ratio gain, which degrade conversion efficiency when the input voltage changes. The proposed power converter offers both step-up and step-down conversion with 4-phase reconfigurable logic. With an input voltage of 1 V provided by photovoltaic (PV) cells, the proposed converter achieves step-up, step-down and synchronised voltage conversions in four gain modes. These are 1.5 V and 0.5 V for Normal mode, 2 V and 1 V for High mode, 2 V for Double Boost mode, as well as 3 V and 2 V for Super Boost mode with the ripple variation of 14-59 mV. The converter circuit has been simulated in standard 0.18 μm CMOS technology and the results agree with state-of-the-art SC converters. However, our proposed monolithically integrated PV powered circuit achieves a conversion efficiency of 85.26% and provides extra flexibility in terms of gain, which is advantageous for future implantable applications that have a range of inputs. This research is therefore an important step in achieving truly autonomous implantable electronic devices

An Energy-Efficient, Dynamic Voltage Scaling Neural Stimulator for a Proprioceptive Prosthesis

Accepted versio