Towards Secure and Intelligent Diagnosis: Deep Learning and Blockchain Technology for Computer-Aided Diagnosis Systems

Cancer is the second leading cause of death across the world after cardiovascular disease. The survival rate of patients with cancerous tissue can significantly decrease due to late-stage diagnosis. Nowadays, advancements of whole slide imaging scanners have resulted in a dramatic increase of patient data in the domain of digital pathology. Large-scale histopathology images need to be analyzed promptly for early cancer detection which is critical for improving patient's survival rate and treatment planning. Advances of medical image processing and deep learning methods have facilitated the extraction and analysis of high-level features from histopathological data that could assist in life-critical diagnosis and reduce the considerable healthcare cost associated with cancer. In clinical trials, due to the complexity and large variance of collected image data, developing computer-aided diagnosis systems to support quantitative medical image analysis is an area of active research. The first goal of this research is to automate the classification and segmentation process of cancerous regions in histopathology images of different cancer tissues by developing models using deep learning-based architectures. In this research, a framework with different modules is proposed, including (1) data pre-processing, (2) data augmentation, (3) feature extraction, and (4) deep learning architectures. Four validation studies were designed to conduct this research. (1) differentiating benign and malignant lesions in breast cancer (2) differentiating between immature leukemic blasts and normal cells in leukemia cancer (3) differentiating benign and malignant regions in lung cancer, and (4) differentiating benign and malignant regions in colorectal cancer. Training machine learning models, disease diagnosis, and treatment often requires collecting patients' medical data. Privacy and trusted authenticity concerns make data owners reluctant to share their personal and medical data. Motivated by the advantages of Blockchain technology in healthcare data sharing frameworks, the focus of the second part of this research is to integrate Blockchain technology in computer-aided diagnosis systems to address the problems of managing access control, authentication, provenance, and confidentiality of sensitive medical data. To do so, a hierarchical identity and attribute-based access control mechanism using smart contract and Ethereum Blockchain is proposed to securely process healthcare data without revealing sensitive information to an unauthorized party leveraging the trustworthiness of transactions in a collaborative healthcare environment. The proposed access control mechanism provides a solution to the challenges associated with centralized access control systems and ensures data transparency and traceability for secure data sharing, and data ownership

Industrial Applications: New Solutions for the New Era

This book reprints articles from the Special Issue "Industrial Applications: New Solutions for the New Age" published online in the open-access journal Machines (ISSN 2075-1702). This book consists of twelve published articles. This special edition belongs to the "Mechatronic and Intelligent Machines" section

Cyber Security of Critical Infrastructures

Critical infrastructures are vital assets for public safety, economic welfare, and the national security of countries. The vulnerabilities of critical infrastructures have increased with the widespread use of information technologies. As Critical National Infrastructures are becoming more vulnerable to cyber-attacks, their protection becomes a significant issue for organizations as well as nations. The risks to continued operations, from failing to upgrade aging infrastructure or not meeting mandated regulatory regimes, are considered highly significant, given the demonstrable impact of such circumstances. Due to the rapid increase of sophisticated cyber threats targeting critical infrastructures with significant destructive effects, the cybersecurity of critical infrastructures has become an agenda item for academics, practitioners, and policy makers. A holistic view which covers technical, policy, human, and behavioural aspects is essential to handle cyber security of critical infrastructures effectively. Moreover, the ability to attribute crimes to criminals is a vital element of avoiding impunity in cyberspace. In this book, both research and practical aspects of cyber security considerations in critical infrastructures are presented. Aligned with the interdisciplinary nature of cyber security, authors from academia, government, and industry have contributed 13 chapters. The issues that are discussed and analysed include cybersecurity training, maturity assessment frameworks, malware analysis techniques, ransomware attacks, security solutions for industrial control systems, and privacy preservation methods

Advances in Cybercrime Prediction: A Survey of Machine, Deep, Transfer, and Adaptive Learning Techniques

Cybercrime is a growing threat to organizations and individuals worldwide, with criminals using increasingly sophisticated techniques to breach security systems and steal sensitive data. In recent years, machine learning, deep learning, and transfer learning techniques have emerged as promising tools for predicting cybercrime and preventing it before it occurs. This paper aims to provide a comprehensive survey of the latest advancements in cybercrime prediction using above mentioned techniques, highlighting the latest research related to each approach. For this purpose, we reviewed more than 150 research articles and discussed around 50 most recent and relevant research articles. We start the review by discussing some common methods used by cyber criminals and then focus on the latest machine learning techniques and deep learning techniques, such as recurrent and convolutional neural networks, which were effective in detecting anomalous behavior and identifying potential threats. We also discuss transfer learning, which allows models trained on one dataset to be adapted for use on another dataset, and then focus on active and reinforcement Learning as part of early-stage algorithmic research in cybercrime prediction. Finally, we discuss critical innovations, research gaps, and future research opportunities in Cybercrime prediction. Overall, this paper presents a holistic view of cutting-edge developments in cybercrime prediction, shedding light on the strengths and limitations of each method and equipping researchers and practitioners with essential insights, publicly available datasets, and resources necessary to develop efficient cybercrime prediction systems.Comment: 27 Pages, 6 Figures, 4 Table

Towards private and robust machine learning for information security

Many problems in information security are pattern recognition problems. For example, determining if a digital communication can be trusted amounts to certifying that the communication does not carry malicious or secret content, which can be distilled into the problem of recognising the difference between benign and malicious content. At a high level, machine learning is the study of how patterns are formed within data, and how learning these patterns generalises beyond the potentially limited data pool at a practitioner’s disposal, and so has become a powerful tool in information security. In this work, we study the benefits machine learning can bring to two problems in information security. Firstly, we show that machine learning can be used to detect which websites are visited by an internet user over an encrypted connection. By analysing timing and packet size information of encrypted network traffic, we train a machine learning model that predicts the target website given a stream of encrypted network traffic, even if browsing is performed over an anonymous communication network. Secondly, in addition to studying how machine learning can be used to design attacks, we study how it can be used to solve the problem of hiding information within a cover medium, such as an image or an audio recording, which is commonly referred to as steganography. How well an algorithm can hide information within a cover medium amounts to how well the algorithm models and exploits areas of redundancy. This can again be reduced to a pattern recognition problem, and so we apply machine learning to design a steganographic algorithm that efficiently hides a secret message with an image. Following this, we proceed with discussions surrounding why machine learning is not a panacea for information security, and can be an attack vector in and of itself. We show that machine learning can leak private and sensitive information about the data it used to learn, and how malicious actors can exploit vulnerabilities in these learning algorithms to compel them to exhibit adversarial behaviours. Finally, we examine the problem of the disconnect between image recognition systems learned by humans and by machine learning models. While human classification of an image is relatively robust to noise, machine learning models do not possess this property. We show how an attacker can cause targeted misclassifications against an entire data distribution by exploiting this property, and go onto introduce a mitigation that ameliorates this undesirable trait of machine learning

Adversarial Robustness and Robust Meta-Learning for Neural Networks

Despite the overwhelming success of neural networks for pattern recognition, these models behave categorically different from humans. Adversarial examples, small perturbations which are often undetectable to the human eye, easily fool neural networks, demonstrating that neural networks lack the robustness of human classifiers. This thesis comprises a sequence of three parts. First, we motivate the study of defense against adversarial examples with a case study on algorithmic trading in which robustness may be critical for security reasons. Second, we develop methods for hardening neural networks against an adversary, especially in the low-data regime, where meta-learning methods achieve state-of-the-art results. Finally, we discuss several properties of the neural network models we use. These properties are of interest beyond robustness to adversarial examples, and they extend to the broad setting of deep learning

Auditable and performant Byzantine consensus for permissioned ledgers

Permissioned ledgers allow users to execute transactions against a data store, and retain proof of their execution in a replicated ledger. Each replica verifies the transactions’ execution and ensures that, in perpetuity, a committed transaction cannot be removed from the ledger. Unfortunately, this is not guaranteed by today’s permissioned ledgers, which can be re-written if an arbitrary number of replicas collude. In addition, the transaction throughput of permissioned ledgers is low, hampering real-world deployments, by not taking advantage of multi-core CPUs and hardware accelerators. This thesis explores how permissioned ledgers and their consensus protocols can be made auditable in perpetuity; even when all replicas collude and re-write the ledger. It also addresses how Byzantine consensus protocols can be changed to increase the execution throughput of complex transactions. This thesis makes the following contributions: 1. Always auditable Byzantine consensus protocols. We present a permissioned ledger system that can assign blame to individual replicas regardless of how many of them misbehave. This is achieved by signing and storing consensus protocol messages in the ledger and providing clients with signed, universally-verifiable receipts. 2. Performant transaction execution with hardware accelerators. Next, we describe a cloud-based ML inference service that provides strong integrity guarantees, while staying compatible with current inference APIs. We change the Byzantine consensus protocol to execute machine learning (ML) inference computation on GPUs to optimize throughput and latency of ML inference computation. 3. Parallel transactions execution on multi-core CPUs. Finally, we introduce a permissioned ledger that executes transactions, in parallel, on multi-core CPUs. We separate the execution of transactions between the primary and secondary replicas. The primary replica executes transactions on multiple CPU cores and creates a dependency graph of the transactions that the backup replicas utilize to execute transactions in parallel.Open Acces

Handbook of Digital Face Manipulation and Detection

This open access book provides the first comprehensive collection of studies dealing with the hot topic of digital face manipulation such as DeepFakes, Face Morphing, or Reenactment. It combines the research fields of biometrics and media forensics including contributions from academia and industry. Appealing to a broad readership, introductory chapters provide a comprehensive overview of the topic, which address readers wishing to gain a brief overview of the state-of-the-art. Subsequent chapters, which delve deeper into various research challenges, are oriented towards advanced readers. Moreover, the book provides a good starting point for young researchers as well as a reference guide pointing at further literature. Hence, the primary readership is academic institutions and industry currently involved in digital face manipulation and detection. The book could easily be used as a recommended text for courses in image processing, machine learning, media forensics, biometrics, and the general security area

Analysis of System Performance Metrics Towards the Detection of Cryptojacking in IOT Devices

This single-case mechanism study examined the effects of cryptojacking on Internet of Things (IoT) device performance metrics. Cryptojacking is a cyber-threat that involves stealing the computational resources of devices belonging to others to generate cryptocurrencies. The resources primarily include the processing cycles of devices and the additional electricity needed to power this additional load. The literature surveyed showed that cryptojacking has been gaining in popularity and is now one of the top cyberthreats. Cryptocurrencies offer anyone more freedom and anonymity than dealing with traditional financial institutions which make them especially attractive to cybercriminals. Other reasons for the increasing popularity of cryptojacking include a large number of vulnerable devices, the low cost to implement, minimal to no expertise required, and the low risk of getting caught or prosecuted. Internet connected devices are becoming increasingly popular and commonplace. Many of these devices also are inherently insecure and make great targets of threat actors. Although many of these devices are low powered, the sheer number of available devices make up for the lack of processing power. Future research could expand on this study by incorporating machine learning, virtualization, live cryptojacking malware samples, or a combination of those items