166 research outputs found
A Deep Learning Reconstruction Framework for Differential Phase-Contrast Computed Tomography with Incomplete Data
Differential phase-contrast computed tomography (DPC-CT) is a powerful
analysis tool for soft-tissue and low-atomic-number samples. Limited by the
implementation conditions, DPC-CT with incomplete projections happens quite
often. Conventional reconstruction algorithms are not easy to deal with
incomplete data. They are usually involved with complicated parameter selection
operations, also sensitive to noise and time-consuming. In this paper, we
reported a new deep learning reconstruction framework for incomplete data
DPC-CT. It is the tight coupling of the deep learning neural network and DPC-CT
reconstruction algorithm in the phase-contrast projection sinogram domain. The
estimated result is the complete phase-contrast projection sinogram not the
artifacts caused by the incomplete data. After training, this framework is
determined and can reconstruct the final DPC-CT images for a given incomplete
phase-contrast projection sinogram. Taking the sparse-view DPC-CT as an
example, this framework has been validated and demonstrated with synthetic and
experimental data sets. Embedded with DPC-CT reconstruction, this framework
naturally encapsulates the physical imaging model of DPC-CT systems and is easy
to be extended to deal with other challengs. This work is helpful to push the
application of the state-of-the-art deep learning theory in the field of
DPC-CT
Generative Modeling in Sinogram Domain for Sparse-view CT Reconstruction
The radiation dose in computed tomography (CT) examinations is harmful for
patients but can be significantly reduced by intuitively decreasing the number
of projection views. Reducing projection views usually leads to severe aliasing
artifacts in reconstructed images. Previous deep learning (DL) techniques with
sparse-view data require sparse-view/full-view CT image pairs to train the
network with supervised manners. When the number of projection view changes,
the DL network should be retrained with updated sparse-view/full-view CT image
pairs. To relieve this limitation, we present a fully unsupervised score-based
generative model in sinogram domain for sparse-view CT reconstruction.
Specifically, we first train a score-based generative model on full-view
sinogram data and use multi-channel strategy to form highdimensional tensor as
the network input to capture their prior distribution. Then, at the inference
stage, the stochastic differential equation (SDE) solver and data-consistency
step were performed iteratively to achieve fullview projection. Filtered
back-projection (FBP) algorithm was used to achieve the final image
reconstruction. Qualitative and quantitative studies were implemented to
evaluate the presented method with several CT data. Experimental results
demonstrated that our method achieved comparable or better performance than the
supervised learning counterparts.Comment: 11 pages, 12 figure
Sub-volume-based Denoising Diffusion Probabilistic Model for Cone-beam CT Reconstruction from Incomplete Data
Deep learning (DL) has emerged as a new approach in the field of computed
tomography (CT) with many applicaitons. A primary example is CT reconstruction
from incomplete data, such as sparse-view image reconstruction. However,
applying DL to sparse-view cone-beam CT (CBCT) remains challenging. Many models
learn the mapping from sparse-view CT images to the ground truth but often fail
to achieve satisfactory performance. Incorporating sinogram data and performing
dual-domain reconstruction improve image quality with artifact suppression, but
a straightforward 3D implementation requires storing an entire 3D sinogram in
memory and many parameters of dual-domain networks. This remains a major
challenge, limiting further research, development and applications. In this
paper, we propose a sub-volume-based 3D denoising diffusion probabilistic model
(DDPM) for CBCT image reconstruction from down-sampled data. Our DDPM network,
trained on data cubes extracted from paired fully sampled sinograms and
down-sampled sinograms, is employed to inpaint down-sampled sinograms. Our
method divides the entire sinogram into overlapping cubes and processes them in
parallel on multiple GPUs, successfully overcoming the memory limitation.
Experimental results demonstrate that our approach effectively suppresses
few-view artifacts while preserving textural details faithfully
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