Image preprocessing in classification and identification of diabetic eye diseases

Diabetic eye disease (DED) is a cluster of eye problem that affects diabetic patients. Identifying DED is a crucial activity in retinal fundus images because early diagnosis and treatment can eventually minimize the risk of visual impairment. The retinal fundus image plays a significant role in early DED classification and identification. An accurate diagnostic model’s development using a retinal fundus image depends highly on image quality and quantity. This paper presents a methodical study on the significance of image processing for DED classification. The proposed automated classification framework for DED was achieved in several steps: image quality enhancement, image segmentation (region of interest), image augmentation (geometric transformation), and classification. The optimal results were obtained using traditional image processing methods with a new build convolution neural network (CNN) architecture. The new built CNN combined with the traditional image processing approach presented the best performance with accuracy for DED classification problems. The results of the experiments conducted showed adequate accuracy, specificity, and sensitivity. © 2021, The Author(s)

Automatic Identification of Diabetic Macular Edema Using a Transfer Learning-Based Approach

[Abstract] This paper presents a complete system for the automatic identification of pathological Diabetic Macular Edema (DME) cases using Optical Coherence Tomography (OCT) images as source of information. To do so, the system extracts a set of deep features using a transfer learning-based approach from different fully-connected layers and different pre-trained Convolutional Neural Network (CNN) models. Next, the most relevant subset of deep features is identified using representative feature selection methods. Finally, a machine learning strategy is applied to train and test the potential of the identified deep features in the pathological classification process. Satisfactory results were obtained, demonstrating the suitability of the presented system to filter those pathological DME cases, helping the specialist to optimize their diagnostic procedures.Xunta de Galicia; ED431G/01Xunta de Galicia; ED431C 2016-047This work is supported by the Instituto de Salud Carlos III, Government of Spain and FEDER funds through the DTS18/00136 research project and by Ministerio de Ciencia, Innovación y Universidades, Government of Spain through the DPI2015-69948-R and RTI2018-095894-B-I00 research projects. Also, this work has received financial support from the European Union (European Regional Development Fund—ERDF) and the Xunta de Galicia, Centro singular de investigación de Galicia accreditation 2016–2019, Ref. ED431G/01; and Grupos de Referencia Competitiva, Ref. ED431C 2016-047

Multilevel Deep Feature Generation Framework for Automated Detection of Retinal Abnormalities Using OCT Images.

Optical coherence tomography (OCT) images coupled with many learning techniques have been developed to diagnose retinal disorders. This work aims to develop a novel framework for extracting deep features from 18 pre-trained convolutional neural networks (CNN) and to attain high performance using OCT images. In this work, we have developed a new framework for automated detection of retinal disorders using transfer learning. This model consists of three phases: deep fused and multilevel feature extraction, using 18 pre-trained networks and tent maximal pooling, feature selection with ReliefF, and classification using the optimized classifier. The novelty of this proposed framework is the feature generation using widely used CNNs and to select the most suitable features for classification. The extracted features using our proposed intelligent feature extractor are fed to iterative ReliefF (IRF) to automatically select the best feature vector. The quadratic support vector machine (QSVM) is utilized as a classifier in this work. We have developed our model using two public OCT image datasets, and they are named database 1 (DB1) and database 2 (DB2). The proposed framework can attain 97.40% and 100% classification accuracies using the two OCT datasets, DB1 and DB2, respectively. These results illustrate the success of our model

The Role of Medical Image Modalities and AI in the Early Detection, Diagnosis and Grading of Retinal Diseases: A Survey.

Traditional dilated ophthalmoscopy can reveal diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), diabetic macular edema (DME), retinal tear, epiretinal membrane, macular hole, retinal detachment, retinitis pigmentosa, retinal vein occlusion (RVO), and retinal artery occlusion (RAO). Among these diseases, AMD and DR are the major causes of progressive vision loss, while the latter is recognized as a world-wide epidemic. Advances in retinal imaging have improved the diagnosis and management of DR and AMD. In this review article, we focus on the variable imaging modalities for accurate diagnosis, early detection, and staging of both AMD and DR. In addition, the role of artificial intelligence (AI) in providing automated detection, diagnosis, and staging of these diseases will be surveyed. Furthermore, current works are summarized and discussed. Finally, projected future trends are outlined. The work done on this survey indicates the effective role of AI in the early detection, diagnosis, and staging of DR and/or AMD. In the future, more AI solutions will be presented that hold promise for clinical applications