Using integrating spheres as absorption cells: path-length distribution and application of Beer's law

We have modeled the path-length distribution in an integrating sphere used as a multipass optical cell for absorption measurements. The measured radiant flux as a function of analyte concentration is nonlinear as a result, deviating from that expected for a single path length. We have developed a full numerical model and introduce a new analytical relationship that describes this behavior for high reflectivity spheres. We have tested both models by measuring the optical absorption of methane at 1651nm in a 50mm diameter sphere, with good agreement with experimental data in the absorption range 0-0.01cm -1 . Our results compare well with previous work on the temporal response of integrating spheres

Cartographic algorithms : problems of implementation and evaluation and the impact of digitising errors

CISRG discussion paper ;

A Method of Drusen Measurement Based on the Geometry of Fundus Reflectance

BACKGROUND: The hallmarks of age-related macular degeneration, the leading cause of blindness in the developed world, are the subretinal deposits known as drusen. Drusen identification and measurement play a key role in clinical studies of this disease. Current manual methods of drusen measurement are laborious and subjective. Our purpose was to expedite clinical research with an accurate, reliable digital method. METHODS: An interactive semi-automated procedure was developed to level the macular background reflectance for the purpose of morphometric analysis of drusen. 12 color fundus photographs of patients with age-related macular degeneration and drusen were analyzed. After digitizing the photographs, the underlying background pattern in the green channel was leveled by an algorithm based on the elliptically concentric geometry of the reflectance in the normal macula: the gray scale values of all structures within defined elliptical boundaries were raised sequentially until a uniform background was obtained. Segmentation of drusen and area measurements in the central and middle subfields (1000 μm and 3000 μm diameters) were performed by uniform thresholds. Two observers using this interactive semi-automated software measured each image digitally. The mean digital measurements were compared to independent stereo fundus gradings by two expert graders (stereo Grader 1 estimated the drusen percentage in each of the 24 regions as falling into one of four standard broad ranges; stereo Grader 2 estimated drusen percentages in 1% to 5% intervals). RESULTS: The mean digital area measurements had a median standard deviation of 1.9%. The mean digital area measurements agreed with stereo Grader 1 in 22/24 cases. The 95% limits of agreement between the mean digital area measurements and the more precise stereo gradings of Grader 2 were -6.4 % to +6.8 % in the central subfield and -6.0 % to +4.5 % in the middle subfield. The mean absolute differences between the digital and stereo gradings 2 were 2.8 +/- 3.4% in the central subfield and 2.2 +/- 2.7% in the middle subfield. CONCLUSIONS: Semi-automated, supervised drusen measurements may be done reproducibly and accurately with adaptations of commercial software. This technique for macular image analysis has potential for use in clinical research

Applied computational geometry: Towards robust solutions of basic problems

AbstractGeometric computations, like all numerical procedures, are extremely prone to roundoff error. However, virtually none of the numerical analysis literature directly applies to geometric calculations. Even for line intersection, the most basic geometric operation, there is no robust and efficient algorithm. Compounding the difficulties, many geometric algorithms perform iterations of calculations reusing previously computed data. In this paper, we explore some of the main issues in geometric computations and the methods that have been proposed to handle roundoff errors. In particular, we focus on one method and apply it to a general iterative intersection problem. Our initial results seem promising and will hopefully lead to robust solutions for more complex problems of applied computational geometry

Two-color holography concept (T-CHI)

The Material Processing in the Space Program of NASA-MSFC was active in developing numerous optical techniques for the characterization of fluids in the vicinity of various materials during crystallization and/or solidification. Two-color holographic interferometry demonstrates that temperature and concentration separation in transparent (T-CHI) model systems is possible. The experiments were performed for particular (succinonitrile) systems. Several solutions are possible in Microgravity Sciences and Applications (MSA) experiments on future Shuttle missions. The theory of the T-CHI concept is evaluated. Although particular cases are used for explanations, the concepts developed will be universal. A breadboard system design is also presented for ultimate fabrication and testing of theoretical findings. New developments in holography involving optical fibers and diode lasers are also incorporated

Correction of Errors During The Manufacture by Computer Numerical Control (CNC) of Blades for an Axial Hydrokinetic Turbine

The design and manufacture of new systems for providing electric power to non-interconnected areas is one of the challenges for engineering. There are several alternatives, including water or wind-power generation systems, where hydrokinetic turbines are highlighted. This work establishes the methodology, identification and correction of errors generated during the manufacture by machining, using CAD/CAPP/CAM techniques, for an axial hydrokinetic turbine. During the manufacturing process, the generation of an error on the edges of the blades was identified, which was attributed to problems in the design of the model since the degrees of freedom of the manufacturing system used were not considered. For the manufacture of complex surfaces in the design of models, the most extreme points of the surfaces in contact must match the tangent edges to ensure that the tools of machining can reach them with the trajectories generated from the CAM