Towards the identification of spatially resolved mechanical properties in tissues and materials: State of the art, current challenges and opportunities in the field of flow measurements

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.This work is focused on optical methods that provide tomographic reconstructions of the structure of materials and tissues. Phase information can also be used to measure 3-D displacement and strain fields with interferometric sensitivity. Different approaches are presented, including recent developments in phase contrast wavelength scanning interferometry and a combination of optical coherence tomography and digital volume correlation to estimate elastic properties of synthetic phantoms and porcine corneas. Inversion algorithms based on finite elements and the Virtual Fields Method (VFM) are used to extract mechanical properties from the knowledge of the applied loads, geometry and measured deformation fields. Current efforts into extending these methods into single shot techniques have the potential of expanding the range of applications to study dynamic events such as micro-flows in engineering and biological systems in which scattering particles are transported in a flow, e.g. tribology, microfluidic devices, cell migration or multiphase flows

Flow-based fabrication: An integrated computational workflow for design and digital additive manufacturing of multifunctional heterogeneously structured objects

Structural hierarchy and material organization in design are traditionally achieved by combining discrete homogeneous parts into functional assemblies where the shape or surface is the determining factor in achieving function. In contrast, biological structures express higher levels of functionality on a finer scale through volumetric cellular constructs that are heterogeneous and complex. Despite recent advancements in additive manufacturing of functionally graded materials, the limitations associated with computational design and digital fabrication of heterogeneous materials and structures frame and limit further progress. Conventional computer-aided design tools typically contain geometric and topologic data of virtual constructs, but lack robust means to integrate material composition properties within virtual models. We present a seamless computational workflow for the design and direct digital fabrication of multi-material and multi-scale structured objects. The workflow encodes for and integrates domain-specific meta-data relating to local, regional and global feature resolution of heterogeneous material organizations. We focus on water-based materials and demonstrate our approach by additively manufacturing diverse constructs associating shape-informing variable flow rates and material properties to mesh-free geometric primitives. The proposed workflow enables virtual-to-physical control of constructs where structural, mechanical and optical gradients are achieved through a seamless design-to-fabrication tool with localized control. An enabling technology combining a robotic arm and a multi-syringe multi nozzle deposition system is presented. Proposed methodology is implemented and full-scale demonstrations are included

Large-eddy simulation and wall modelling of turbulent channel flow

We report large-eddy simulation (LES) of turbulent channel flow. This LES neither resolves nor partially resolves the near-wall region. Instead, we develop a special near-wall subgrid-scale (SGS) model based on wall-parallel filtering and wall-normal averaging of the streamwise momentum equation, with an assumption of local inner scaling used to reduce the unsteady term. This gives an ordinary differential equation (ODE) for the wall shear stress at every wall location that is coupled with the LES. An extended form of the stretched-vortex SGS model, which incorporates the production of near-wall Reynolds shear stress due to the winding of streamwise momentum by near-wall attached SGS vortices, then provides a log relation for the streamwise velocity at the top boundary of the near-wall averaged domain. This allows calculation of an instantaneous slip velocity that is then used as a ‘virtual-wall’ boundary condition for the LES. A Kármán-like constant is calculated dynamically as part of the LES. With this closure we perform LES of turbulent channel flow for Reynolds numbers Re_τ based on the friction velocity u_τ and the channel half-width δ in the range 2 × 10^3 to 2 × 10^7. Results, including SGS-extended longitudinal spectra, compare favourably with the direct numerical simulation (DNS) data of Hoyas & Jiménez (2006) at Re_τ = 2003 and maintain an O(1) grid dependence on Re_τ

Efficient Resource Management Mechanism for 802.16 Wireless Networks Based on Weighted Fair Queuing

Wireless Networking continues on its path of being one of the most commonly used means of communication. The evolution of this technology has taken place through the design of various protocols. Some common wireless protocols are the WLAN, 802.16 or WiMAX, and the emerging 802.20, which specializes in high speed vehicular networks, taking the concept from 802.16 to higher levels of performance. As with any large network, congestion becomes an important issue. Congestion gains importance as more hosts join a wireless network. In most cases, congestion is caused by the lack of an efficient mechanism to deal with exponential increases in host devices. This can effectively lead to very huge bottlenecks in the network causing slow sluggish performance, which may eventually reduce the speed of the network. With continuous advancement being the trend in this technology, the proposal of an efficient scheme for wireless resource allocation is an important solution to the problem of congestion. The primary area of focus will be the emerging standard for wireless networks, the 802.16 or “WiMAX”. This project, attempts to propose a mechanism for an effective resource management mechanism between subscriber stations and the corresponding base station

SO(3)-invariant asymptotic observers for dense depth field estimation based on visual data and known camera motion

In this paper, we use known camera motion associated to a video sequence of a static scene in order to estimate and incrementally refine the surrounding depth field. We exploit the SO(3)-invariance of brightness and depth fields dynamics to customize standard image processing techniques. Inspired by the Horn-Schunck method, we propose a SO(3)-invariant cost to estimate the depth field. At each time step, this provides a diffusion equation on the unit Riemannian sphere that is numerically solved to obtain a real time depth field estimation of the entire field of view. Two asymptotic observers are derived from the governing equations of dynamics, respectively based on optical flow and depth estimations: implemented on noisy sequences of synthetic images as well as on real data, they perform a more robust and accurate depth estimation. This approach is complementary to most methods employing state observers for range estimation, which uniquely concern single or isolated feature points.Comment: Submitte