108 research outputs found
Electrocardiogram pattern recognition and analysis based on artificial neural networks and support vector machines: a review.
Computer systems for Electrocardiogram (ECG) analysis support the clinician in tedious tasks (e.g., Holter ECG monitored in Intensive Care Units) or in prompt detection of dangerous events (e.g., ventricular fibrillation). Together with clinical applications (arrhythmia detection and heart rate variability analysis), ECG is currently being investigated in biometrics (human identification), an emerging area receiving increasing attention. Methodologies for clinical applications can have both differences and similarities with respect to biometrics. This paper reviews methods of ECG processing from a pattern recognition perspective. In particular, we focus on features commonly used for heartbeat classification. Considering the vast literature in the field and the limited space of this review, we dedicated a detailed discussion only to a few classifiers (Artificial Neural Networks and Support Vector Machines) because of their popularity; however, other techniques such as Hidden Markov Models and Kalman Filtering will be also mentioned
Unsupervised Heart-rate Estimation in Wearables With Liquid States and A Probabilistic Readout
Heart-rate estimation is a fundamental feature of modern wearable devices. In
this paper we propose a machine intelligent approach for heart-rate estimation
from electrocardiogram (ECG) data collected using wearable devices. The novelty
of our approach lies in (1) encoding spatio-temporal properties of ECG signals
directly into spike train and using this to excite recurrently connected
spiking neurons in a Liquid State Machine computation model; (2) a novel
learning algorithm; and (3) an intelligently designed unsupervised readout
based on Fuzzy c-Means clustering of spike responses from a subset of neurons
(Liquid states), selected using particle swarm optimization. Our approach
differs from existing works by learning directly from ECG signals (allowing
personalization), without requiring costly data annotations. Additionally, our
approach can be easily implemented on state-of-the-art spiking-based
neuromorphic systems, offering high accuracy, yet significantly low energy
footprint, leading to an extended battery life of wearable devices. We
validated our approach with CARLsim, a GPU accelerated spiking neural network
simulator modeling Izhikevich spiking neurons with Spike Timing Dependent
Plasticity (STDP) and homeostatic scaling. A range of subjects are considered
from in-house clinical trials and public ECG databases. Results show high
accuracy and low energy footprint in heart-rate estimation across subjects with
and without cardiac irregularities, signifying the strong potential of this
approach to be integrated in future wearable devices.Comment: 51 pages, 12 figures, 6 tables, 95 references. Under submission at
Elsevier Neural Network
Detection of electrocardiogram QRS complex based on modified adaptive threshold
It is essential for medical diagnoses to analyze Electrocardiogram (ECG signal). The core of this analysis is to detect the QRS complex. A modified approach is suggested in this work for QRS detection of ECG signals using existing database of arrhythmias. The proposed approach starts with the same steps of previous approaches by filtering the ECG. The filtered signal is then fed to a differentiator to enhance the signal. The modified adaptive threshold method which is suggested in this work, is used to detect QRS complex. This method uses a new approach for adapting threshold level, which is based on statistical analysis of the signal. Forty-eight records from an existing arrhythmia database have been tested using the modified method. The result of the proposed method shows the high performance metrics with sensitivity of 99.62% and a positive predictivity of 99.88% for QRS complex detection
Neuromorphic solutions: Digital implementation of bio-inspired spiking neural network for electrocardiogram classification
Conventional techniques of off-chip processing for wearable devices cause high hardware resource usage which leads to heat generation and increased power consumption. Hence, edge computing methods such as neuromorphic computing are considered the most promising modern technology to replace conventional processing. It is beneficial to employ neuromorphic processing in electrocardiogram (ECG) classification, enabling engineers to overcome the constraints of heat generation caused by hardware utilization. Thus, this work aims to investigate common building blocks in a spiking neural network (SNN), analyze the spike-based plasticity mechanism and implement ECG classification on a neuromorphic circuit. The MIT-BIH Arrhythmia database (MITDB) is preprocessed in MATLAB, then used to train and test an SNN designed for field programmable gate arrays (FPGA), employing spike-based plasticity and Izhikevich neurons. The behaviour of spike timing dependent plasticity (STDP) in a neuromorphic circuit is also visualized in this work. The state-of the-art performance of this work lies in providing a generic mechanism to adapt ECG classification into a neuromorphic solution, a non-Von Neumann architecture. The proposed digital design utilizes 1.058% of hardware resources on a Zedboard. Application-wise, this work provides a foundation for development of neuromorphic computing in wearable medical devices that perform continuous monitoring of ECG
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
ECG classification and prognostic approach towards personalized healthcare
A very important aspect of personalized healthcare is to continuously monitor an individual’s health using wearable biomedical devices and essentially to analyse and if possible to predict potential health hazards that may prove fatal if not treated in time. The prediction aspect embedded in the system helps in avoiding delays in providing timely medical treatment, even before an individual reaches a critical condition. Despite of the availability of modern wearable health monitoring devices, the real-time analyses and prediction component seems to be missing with these devices. The research work illustrated in this paper, at an outset, focussed on constantly monitoring an individual's ECG readings using a wearable 3-lead ECG kit and more importantly focussed on performing real-time analyses to detect arrhythmia to be able to identify and predict heart risk. Also, current research shows extensive use of heart rate variability (HRV) analysis and machine learning for arrhythmia classification, which however depends on the morphology of the ECG waveforms and the sensitivity of the ECG equipment. Since a wearable 3-lead ECG kit was used, the accuracy of classification had to be dealt with at the machine learning phase, so a unique feature extraction method was developed to increase the accuracy of classification. As a case study a very widely used Arrhythmia database (MIT-BIH, Physionet) was used to develop learning, classification and prediction models. Neuralnet fitting models on the extracted features showed mean-squared error of as low as 0.0085 and regression value as high as 0.99. Current experiments show 99.4% accuracy using k-NN Classification models and show values of Cross-Entropy Error of 7.6 and misclassification error value of 1.2 on test data using scaled conjugate gradient pattern matching algorithms. Software components were developed for wearable devices that took ECG readings from a 3-Lead ECG data acquisition kit in real time, de-noised, filtered and relayed the sample readings to the tele health analytical server. The analytical server performed the classification and prediction tasks based on the trained classification models and could raise appropriate alarms if ECG abnormalities of V (Premature Ventricular Contraction: PVC), A (Atrial Premature Beat: APB), L (Left bundle branch block beat), R (Right bundle branch block beat) type annotations in MITDB were detected. The instruments were networked using IoT (Internet of Things) devices and abnormal ECG events related to arrhythmia, from analytical server could be logged using an FHIR web service implementation, according to a SNOMED coding system and could be accessed in Electronic Health Record by the concerned medic to take appropriate and timely decisions. The system focused on ‘preventive care rather than remedial cure’ which has become a major focus of all the health care and cure institutions across the globe
REAL TIME SYSTEM FOR EFFICIENT PROCESSING OF CARDIAC ARRHYTHMIAS SIGNALS
Cardiac arrhythmias is a very uncommon life threating arrhythmia which can even cause sudden death. Healthcare professionals are always looking to find out the ways in order to reduce the death rate. The new method of feature extraction and classification of arrhythmias has been developed by the authors of this paper in their previous works. In this paper, authors have proposed the methodology for the development of a real-time system for efficient processing of arrhythmic signals in order to differentiate between normal and abnormal patients. The purpose of this work is to develop a real-time system for processing the real-time signals or signals obtained from MIT-BIH arrhythmia database. For carrying out this work, we have taken the signals from MIT-BIH Supraventricular arrhythmia  database and MIT-BIH Fantasia database. Authors have achieved 100% accuracy by using this method. Keywords: MIT-BIH, Cardiac arrhythmias, real-time system
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