The Nimbus 6 data catalog, volume 12: Data orbits 9227 through 10043

Nimbus 6 was successfully launched from the Western Test Range, Vandenberg Air Force Base, California at 08 hr. 12 min. 00 sec. GMT on 12 June 1975. The orbit was nearly circular at 1093 x 1105 km. Satellite operations from launch through 14 July (orbit 425) consisted of engineering evaluation of all spacecraft systems. As a result of that effort, data reception, accountability and processing were intermittent during that period. This volume reflects the operational changes that occurred to each individual subsystem on a bi-monthly basis. Also this volume incorporates significant findings and various subsystem summaries as detailed by the respective experimenter. During orbit 9793 (12 June 1977) Nimbus 6 successfully completed two years of operations

Forecasting Class III and Class IV Milk Prices

Despite the growing volume, trading in milk remains small in comparison to grain and livestock. Part of the reason for limited trading volume is that dairy futures trading is very new compared to grain and livestock trading. There is less experience with risk management strategies and a much smaller research base with respect to basis relationships and price forecasting. Dairy farmers are still "feeling their way." The purpose of this study is to provide a systematic, user-friendly method for forecasting Class III and Class IV prices. The user is allowed to vary regional milk production and stocks of manufactured dairy products to evaluate the sensitivity of point estimates. A sequential process is developed to predict Class III milk prices up to 12 months in advance using widely-published outlook data as predictor variables. The first stage involves deriving monthly U.S. milk supply forecasts using trend extrapolations for regional milk cow numbers and milk production per cow. Users may modify trend values based on personal expectations. In the second stage, the projected monthly U.S. milk supply is allocated to Class III and Class IV manufactured products (butter, cheddar cheese, nonfat dry milk, and dry whey). Underlying these forecasts is a set of econometric relationships that estimate production of the manufactured products based on total milk production and other variables.

[68Ga]-DOTATOC-PET/CT for meningioma IMRT treatment planning

<p>Abstract</p> <p>Purpose</p> <p>The observation that human meningioma cells strongly express somatostatin receptor (SSTR 2) was the rationale to analyze retrospectively in how far DOTATOC PET/CT is helpful to improve target volume delineation for intensity modulated radiotherapy (IMRT).</p> <p>Patients and Methods</p> <p>In 26 consecutive patients with preferentially skull base meningioma, diagnostic magnetic resonance imaging (MRI) and planning-computed tomography (CT) was complemented with data from [⁶⁸Ga]-DOTA-D Phe¹-Tyr³-Octreotide (DOTATOC)-PET/CT. Image fusion of PET/CT, diagnostic computed tomography, MRI and radiotherapy planning CT as well as target volume delineation was performed with OTP-Masterplan^®. Initial gross tumor volume (GTV) definition was based on MRI data only and was secondarily complemented with DOTATOC-PET information. Irradiation was performed as EUD based IMRT, using the Hyperion Software package.</p> <p>Results</p> <p>The integration of the DOTATOC data led to additional information concerning tumor extension in 17 of 26 patients (65%). There were major changes of the clinical target volume (CTV) which modify the PTV in 14 patients, minor changes were realized in 3 patients. Overall the GTV-MRI/CT was larger than the GTV-PET in 10 patients (38%), smaller in 13 patients (50%) and almost the same in 3 patients (12%). Most of the adaptations were performed in close vicinity to bony skull base structures or after complex surgery. Median GTV based on MRI was 18.1 cc, based on PET 25.3 cc and subsequently the CTV was 37.4 cc. Radiation planning and treatment of the DOTATOC-adapted volumes was feasible.</p> <p>Conclusion</p> <p>DOTATOC-PET/CT information may strongly complement patho-anatomical data from MRI and CT in cases with complex meningioma and is thus helpful for improved target volume delineation especially for skull base manifestations and recurrent disease after surgery.</p

How does light intensity physical activity associate with adult cardiometabolic health and mortality? Systematic review with meta-analysis of experimental and observational studies

Aim To assess the relationship between time spent in light physical activity and cardiometabolic health and mortality in adults. Design Systematic review and meta-analysis. Data sources Searches in Medline, Embase, PsycInfo, CINAHL and three rounds of hand searches. Eligibility criteria for selecting studies Experimental (including acute mechanistic studies and physical activity intervention programme) and observational studies (excluding case and case-control studies) conducted in adults (aged >= 18 years) published in English before February 2018 and reporting on the relationship between light physical activity (<3 metabolic equivalents) and cardiometabolic health outcomes or all-cause mortality. Study appraisal and synthesis Study quality appraisal with QUALSYST tool and random effects inverse variance meta-analysis. Results Seventy-two studies were eligible including 27 experimental studies (and 45 observational studies). Mechanistic experimental studies showed that short but frequent bouts of light-intensity activity throughout the day reduced postprandial glucose (-17.5%; 95% CI -26.2 to -8.7) and insulin (-25.1%; 95% CI -31.8 to -18.3) levels compared with continuous sitting, but there was very limited evidence for it affecting other cardiometabolic markers. Three light physical activity programme intervention studies (n ranging from 12 to 58) reduced adiposity, improved blood pressure and lipidaemia; the programmes consisted of activity of > 150 min/week for at least 12 weeks. Six out of eight prospective observational studies that were entered in the meta-analysis reported that more time spent in daily light activity reduced risk of all-cause mortality (pooled HR 0.71; 95% CI 0.62 to 0.83). Conclusions Light-intensity physical activity could play a role in improving adult cardiometabolic health and reducing mortality risk. Frequent short bouts of light activity improve glycaemic control. Nevertheless, the modest volume of the prospective epidemiological evidence base and the moderate consistency between observational and laboratory evidence inhibits definitive conclusions

Evaluating the citywide Edinburgh 20mph speed limit intervention effects on traffic speed and volume: A pre-post observational evaluation.

OBJECTIVES: Traffic speed is important to public health as it is a major contributory factor to collision risk and casualty severity. 20mph (32km/h) speed limit interventions are an increasingly common approach to address this transport and health challenge, but a more developed evidence base is needed to understand their effects. This study describes the changes in traffic speed and traffic volume in the City of Edinburgh, pre- and 12 months post-implementation of phased city-wide 20mph speed limits from 2016-2018. METHODS: The City of Edinburgh Council collected speed and volume data across one full week (24 hours a day) pre- and post-20mph speed limits for 66 streets. The pre- and post-speed limit intervention data were compared using measures of central tendency, dispersion, and basic t-tests. The changes were assessed at different aggregations and evaluated for statistical significance (alpha = 0.05). A mixed effects model was used to model speed reduction, in the presence of key variables such as baseline traffic speed and time of day. RESULTS: City-wide, a statistically significant reduction in mean speed of 1.34mph (95% CI 0.95 to 1.72) was observed at 12 months post-implementation, representing a 5.7% reduction. Reductions in speed were observed throughout the day and across the week, and larger reductions in speed were observed on roads with higher initial speeds. Mean 7-day volume of traffic was found to be lower by 86 vehicles (95% CI: -112 to 286) representing a reduction of 2.4% across the city of Edinburgh (p = 0.39) but with the direction of effect uncertain. CONCLUSIONS: The implementation of the city-wide 20mph speed limit intervention was associated with meaningful reductions in traffic speeds but not volume. The reduction observed in road traffic speed may act as a mechanism to lessen the frequency and severity of collisions and casualties, increase road safety, and improve liveability

Effects of Varying Load Intensity on Skeletal Muscle Damage Between Two Isovolumic Resistance Exercise Bouts

International Journal of Exercise Science 15(4): 1212-1221, 2022. There are limited data comparing the efficacy of resistance loads within the hypertrophy range for promoting muscular growth, particularly when similar training volumes are utilized. The purpose of this study was to determine if two similar volume-loads, utilizing different intensities, would produce dissimilar muscular damage and inflammation. Eleven resistance-trained, college-aged males participated in this study. After testing 1RM barbell squats, participants completed two similar volume-load barbell squat sessions at two different resistance loads (67% and 85% of 1RM) on two separate visits. Venous blood samples were collected at baseline and one hour after completion of each exercise session. Plasma was isolated and analyzed for myoglobin and C-reactive protein (CRP) expression via ELISA. Plasma myoglobin expression was significantly elevated above baseline (BASE) values only after the 85% of 1RM (HHL) session (p =0.031), though the 67% (LHL) trial (p = 0.054; h2 = 0.647) was approaching significance (BASE: 1.42+.12 ng/mL; LHL: 4.65+1.13 ng/mL; HHL: 5.00+1.01 ng/mL). No changes in plasma CRP were observed. Despite attempts to equate volumes between resistances, mean total volume-load was significantly higher during the 67% of 1RM trial than during the 85% trial. Resistance loads at 85% of 1RM inflict significantly increased muscle damage over baseline values, even when significantly less total volume was lifted during the 85% trial. Individuals looking to maximize strength and hypertrophy during general training or during rehabilitation may benefit from these findings when determining the appropriate training load

Shock-Wave Equations of State for Rocks and Minerals

A method is proposed for estimating the zero-pressure parameters of the high-pressure, high-temperature phases formed by intense shock loading of rocks and minerals. The method involves an empirical relationship between the zero-pressure mean molar volume and the slope at the base of the P-V curve. Equations of state are fitted to shock-wave data for eighteen rocks and minerals. Most of the materials collapsed to a denser phase or assemblage of phases when shocked to sufficiently high pressure. If a phase change occurs, parameters of the high-pressure phase are found for a range of ρ_0 the raw Hugoniot and an estimated metastable Hugoniot. The polymorphic transitions involve a considerable reduction in volume, ranging from 33 to 49% for feldspar and quartz-rich rocks such as albitite, anorthosite, and granite, 20% for such basic rocks as diabase and dunite, and about 12% for some dense already closely packed minerals such as spinel, hematite, and magnetite. The parameter (dK/dP)_0, which is related to the Grüneisen ratio, is found to decrease across phase changes and upon iron substitution

HausaNLP at SemEval-2023 Task 12: Leveraging African Low Resource TweetData for Sentiment Analysis

We present the findings of SemEval-2023 Task 12, a shared task on sentiment analysis for low-resource African languages using Twitter dataset. The task featured three subtasks; subtask A is monolingual sentiment classification with 12 tracks which are all monolingual languages, subtask B is multilingual sentiment classification using the tracks in subtask A and subtask C is a zero-shot sentiment classification. We present the results and findings of subtask A, subtask B and subtask C. We also release the code on github. Our goal is to leverage low-resource tweet data using pre-trained Afro-xlmr-large, AfriBERTa-Large, Bert-base-arabic-camelbert-da-sentiment (Arabic-camelbert), Multilingual-BERT (mBERT) and BERT models for sentiment analysis of 14 African languages. The datasets for these subtasks consists of a gold standard multi-class labeled Twitter datasets from these languages. Our results demonstrate that Afro-xlmr-large model performed better compared to the other models in most of the languages datasets. Similarly, Nigerian languages: Hausa, Igbo, and Yoruba achieved better performance compared to other languages and this can be attributed to the higher volume of data present in the languages

Efficacy and safety profile of a novel technique, ThuLEP (Thulium laser enucleation of the prostate) for the treatment of benign prostate hypertrophy. Our experience on 148 patients.

BACKGROUND: Over the past years laser technology has played a predominant role in prostate surgery, for the treatment of benign prostate hypertrophy (BPH). Various laser devices have been introduced in clinical practice, showing good results in terms of complications and urodynamic outcomes efficacy compared with TURP and Open Prostatectomy. In this study we describe the efficacy and the safety profile of a novel laser technique, ThuLEP (Thulium Laser Enucleation of Prostate) that permits a complete anatomical endoscopic enucleation of prostatic adenoma independently to prostate size. METHODS: 148 patients with a mean age of 68.2 years were enrolled between September 2009 and March 2012 (36 months), and treated for BPH with ThuLEP. Every patient was evaluated at base line according to: Digital Rectal Examination (DRE), prostate volume, Post-Voided volume (PVR), International Prostate Symptoms Score (I-PSS), International Index of Erectile Function-5 (IIEF-5), Quality of Life (QoL), PSA values, urine analysis and urine culture, uroflowmetry. The same evaluation was conducted after a 12 month follow-up. ThuLEP was performed by 2 expert surgeons. RESULTS: Our data showed a better post-operative outcome in terms of catheter removal, blood loss, TURP syndrome, clot retention and residual tissue compared to large series of TURP and OP. Only 1.3% of patients had bladder wall injury during morcellation. I-PSS, Qmax, Prostate Volume, QoL and PVR showed a highly significant improvement at 12 month follow-up in comparison to preoperative assessment. CONCLUSION: ThuLEP represent an innovative option in patients with BPH. It is a size independent surgical endoscopic technique and it can be considered the real alternative, at this time, to TURP and even more to Open Prostatectomy for large prostate, with a complete removal of adenoma and with a low complication rate