Sparse MRI and CT Reconstruction

Sparse signal reconstruction is of the utmost importance for efficient medical imaging, conducting accurate screening for security and inspection, and for non-destructive testing. The sparsity of the signal is dictated by either feasibility, or the cost and the screening time constraints of the system. In this work, two major sparse signal reconstruction systems such as compressed sensing magnetic resonance imaging (MRI) and sparse-view computed tomography (CT) are investigated. For medical CT, a limited number of views (sparse-view) is an option for whether reducing the amount of ionizing radiation or the screening time and the cost of the procedure. In applications such as non-destructive testing or inspection of large objects, like a cargo container, one angular view can take up to a few minutes for only one slice. On the other hand, some views can be unavailable due to the configuration of the system. A problem of data sufficiency and on how to estimate a tomographic image when the projection data are not ideally sufficient for precise reconstruction is one of two major objectives of this work. Three CT reconstruction methods are proposed: algebraic iterative reconstruction-reprojection (AIRR), sparse-view CT reconstruction based on curvelet and total variation regularization (CTV), and sparse-view CT reconstruction based on nonconvex L1-L2 regularization. The experimental results confirm a high performance based on subjective and objective quality metrics. Additionally, sparse-view neutron-photon tomography is studied based on Monte-Carlo modelling to demonstrate shape reconstruction, material discrimination and visualization based on the proposed 3D object reconstruction method and material discrimination signatures. One of the methods for efficient acquisition of multidimensional signals is the compressed sensing (CS). A significantly low number of measurements can be obtained in different ways, and one is undersampling, that is sampling below the Shannon-Nyquist limit. Magnetic resonance imaging (MRI) suffers inherently from its slow data acquisition. The compressed sensing MRI (CSMRI) offers significant scan time reduction with advantages for patients and health care economics. In this work, three frameworks are proposed and evaluated, i.e., CSMRI based on curvelet transform and total generalized variation (CT-TGV), CSMRI using curvelet sparsity and nonlocal total variation: CS-NLTV, CSMRI that explores shearlet sparsity and nonlocal total variation: SS-NLTV. The proposed methods are evaluated experimentally and compared to the previously reported state-of-the-art methods. Results demonstrate a significant improvement of image reconstruction quality on different medical MRI datasets

Fast Image Recovery Using Variable Splitting and Constrained Optimization

We propose a new fast algorithm for solving one of the standard formulations of image restoration and reconstruction which consists of an unconstrained optimization problem where the objective includes an $\ell_2$ data-fidelity term and a non-smooth regularizer. This formulation allows both wavelet-based (with orthogonal or frame-based representations) regularization or total-variation regularization. Our approach is based on a variable splitting to obtain an equivalent constrained optimization formulation, which is then addressed with an augmented Lagrangian method. The proposed algorithm is an instance of the so-called "alternating direction method of multipliers", for which convergence has been proved. Experiments on a set of image restoration and reconstruction benchmark problems show that the proposed algorithm is faster than the current state of the art methods.Comment: Submitted; 11 pages, 7 figures, 6 table

An Augmented Lagrangian Approach to the Constrained Optimization Formulation of Imaging Inverse Problems

We propose a new fast algorithm for solving one of the standard approaches to ill-posed linear inverse problems (IPLIP), where a (possibly non-smooth) regularizer is minimized under the constraint that the solution explains the observations sufficiently well. Although the regularizer and constraint are usually convex, several particular features of these problems (huge dimensionality, non-smoothness) preclude the use of off-the-shelf optimization tools and have stimulated a considerable amount of research. In this paper, we propose a new efficient algorithm to handle one class of constrained problems (often known as basis pursuit denoising) tailored to image recovery applications. The proposed algorithm, which belongs to the family of augmented Lagrangian methods, can be used to deal with a variety of imaging IPLIP, including deconvolution and reconstruction from compressive observations (such as MRI), using either total-variation or wavelet-based (or, more generally, frame-based) regularization. The proposed algorithm is an instance of the so-called "alternating direction method of multipliers", for which convergence sufficient conditions are known; we show that these conditions are satisfied by the proposed algorithm. Experiments on a set of image restoration and reconstruction benchmark problems show that the proposed algorithm is a strong contender for the state-of-the-art.Comment: 13 pages, 8 figure, 8 tables. Submitted to the IEEE Transactions on Image Processin

NESTA: A Fast and Accurate First-order Method for Sparse Recovery

Accurate signal recovery or image reconstruction from indirect and possibly undersampled data is a topic of considerable interest; for example, the literature in the recent field of compressed sensing is already quite immense. Inspired by recent breakthroughs in the development of novel first-order methods in convex optimization, most notably Nesterov's smoothing technique, this paper introduces a fast and accurate algorithm for solving common recovery problems in signal processing. In the spirit of Nesterov's work, one of the key ideas of this algorithm is a subtle averaging of sequences of iterates, which has been shown to improve the convergence properties of standard gradient-descent algorithms. This paper demonstrates that this approach is ideally suited for solving large-scale compressed sensing reconstruction problems as 1) it is computationally efficient, 2) it is accurate and returns solutions with several correct digits, 3) it is flexible and amenable to many kinds of reconstruction problems, and 4) it is robust in the sense that its excellent performance across a wide range of problems does not depend on the fine tuning of several parameters. Comprehensive numerical experiments on realistic signals exhibiting a large dynamic range show that this algorithm compares favorably with recently proposed state-of-the-art methods. We also apply the algorithm to solve other problems for which there are fewer alternatives, such as total-variation minimization, and convex programs seeking to minimize the l1 norm of Wx under constraints, in which W is not diagonal